KNApSAcK Metabolite C00000800
Metabolite
KNApSAcK Entry
| id | C00000800 |
|---|---|
| Name | PF / Phosphonoformic acid |
| CAS RN | 4428-95-9 |
| Standard InChI | InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6) |
| Standard InChI (Main Layer) | InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 8860 |
Link
ChEMBL
| By standard InChI | CHEMBL666 |
|---|---|
| By standard InChI Main Layer | CHEMBL666 |
KEGG
| By LinkDB | C06456 |
|---|
CTD
| By CAS RN | D017245 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Streptomycetaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Streptomyces hygroscopicus | 1912 | Streptomycetaceae | Bacteria |
Human Protein / Gene in interaction
95 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | CHEMBL666 |
CHEMBL1909136
(2)
|
1 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | CHEMBL666 |
CHEMBL1909139
(2)
|
0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | CHEMBL666 |
CHEMBL1909131
(2)
|
0 / 3 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | CHEMBL666 |
CHEMBL1909190
(2)
|
2 / 2 |
| P08246 | Neutrophil elastase | S1A | CHEMBL666 |
CHEMBL1909195
(2)
|
2 / 1 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | CHEMBL666 |
CHEMBL1909215
(2)
|
0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | CHEMBL666 |
CHEMBL1909201
(2)
|
0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | CHEMBL666 |
CHEMBL1909176
(2)
|
0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | CHEMBL666 |
CHEMBL828084
(1)
|
0 / 0 |
| P29466 | Caspase-1 | C14 | CHEMBL666 |
CHEMBL1909193
(2)
|
0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | CHEMBL666 |
CHEMBL1909198
(2)
|
0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | CHEMBL666 |
CHEMBL1909199
(2)
|
0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | CHEMBL666 |
CHEMBL1909197
(2)
|
2 / 2 |
| P00918 | Carbonic anhydrase 2 | Lyase | CHEMBL666 |
CHEMBL828765
(1)
CHEMBL1909123
(2)
|
1 / 2 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | CHEMBL666 |
CHEMBL1909092
(2)
|
0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | CHEMBL666 |
CHEMBL1909169
(2)
|
1 / 1 |
| P25021 | Histamine H2 receptor | Histamine receptor | CHEMBL666 |
CHEMBL1909157
(2)
|
0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | CHEMBL666 |
CHEMBL1909156
(2)
|
0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | CHEMBL666 |
CHEMBL1909143
(2)
|
1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | CHEMBL666 |
CHEMBL1909174
(2)
|
0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | CHEMBL666 |
CHEMBL1909090
(2)
|
0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | CHEMBL666 |
CHEMBL1909093
(2)
|
0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | CHEMBL666 |
CHEMBL1909127
(2)
|
0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | CHEMBL666 |
CHEMBL1909204
(2)
|
0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | CHEMBL666 |
CHEMBL1909202
(2)
|
0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | CHEMBL666 |
CHEMBL1909135
(2)
|
0 / 1 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | CHEMBL666 |
CHEMBL1909203
(2)
|
1 / 11 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | CHEMBL666 |
CHEMBL1909140
(2)
|
2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | CHEMBL666 |
CHEMBL1909130
(2)
|
0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | CHEMBL666 |
CHEMBL1909120
(2)
|
0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | CHEMBL666 |
CHEMBL1909181
(2)
|
0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | CHEMBL666 |
CHEMBL1909164
(2)
|
0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | CHEMBL666 |
CHEMBL1909214
(2)
|
0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | CHEMBL666 |
CHEMBL1909175
(2)
|
0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | CHEMBL666 |
CHEMBL1909096
(2)
|
1 / 1 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | CHEMBL666 |
CHEMBL1909118
(2)
|
0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | CHEMBL666 |
CHEMBL1909166
(2)
|
1 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | CHEMBL666 |
CHEMBL1909133
(2)
|
0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | CHEMBL666 |
CHEMBL1909158
(2)
|
0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | CHEMBL666 |
CHEMBL1909088
(2)
|
0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | CHEMBL666 |
CHEMBL1909142
(2)
|
0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | CHEMBL666 |
CHEMBL1909101
(2)
|
0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | CHEMBL666 |
CHEMBL1909141
(2)
|
1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | CHEMBL666 |
CHEMBL1909180
(2)
|
0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | CHEMBL666 |
CHEMBL1909146
(2)
|
0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | CHEMBL666 |
CHEMBL1909104
(2)
|
0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | CHEMBL666 |
CHEMBL1909144
(2)
|
0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | CHEMBL666 |
CHEMBL1909100
(2)
|
0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | CHEMBL666 |
CHEMBL1909167
(2)
|
1 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | CHEMBL666 |
CHEMBL841750
(1)
|
0 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | CHEMBL666 |
CHEMBL1909129
(2)
|
0 / 0 |
| P08311 | Cathepsin G | S1A | CHEMBL666 |
CHEMBL1909194
(2)
|
0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | CHEMBL666 |
CHEMBL1909110
(2)
|
1 / 0 |
| P03956 | Interstitial collagenase | M10A | CHEMBL666 |
CHEMBL1909196
(2)
|
0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | CHEMBL666 |
CHEMBL1909119
(2)
|
0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | CHEMBL666 |
CHEMBL1909150
(2)
|
0 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | CHEMBL666 |
CHEMBL1909171
(2)
|
2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | CHEMBL666 |
CHEMBL1909170
(2)
|
0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | CHEMBL666 |
CHEMBL1909122
(2)
|
0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | CHEMBL666 |
CHEMBL1909109
(2)
|
2 / 0 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | CHEMBL666 |
CHEMBL1909205
(2)
|
5 / 10 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | CHEMBL666 |
CHEMBL1909172
(2)
|
1 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | CHEMBL666 |
CHEMBL1909114
(2)
|
0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | CHEMBL666 |
CHEMBL1909125
(2)
|
0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | CHEMBL666 |
CHEMBL1909126
(2)
|
3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | CHEMBL666 |
CHEMBL1909108
(2)
|
0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | CHEMBL666 |
CHEMBL1909124
(2)
|
1 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | CHEMBL666 |
CHEMBL1909200
(2)
|
0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | CHEMBL666 |
CHEMBL1909207
(2)
|
2 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | CHEMBL666 |
CHEMBL1909132
(2)
|
0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | CHEMBL666 |
CHEMBL829122
(1)
|
0 / 1 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | CHEMBL666 |
CHEMBL1909186
(2)
|
0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | CHEMBL666 |
CHEMBL1909145
(2)
|
1 / 1 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | CHEMBL666 |
CHEMBL1909091
(2)
|
1 / 0 |
| P09884 | DNA polymerase alpha catalytic subunit | Transferase | CHEMBL666 |
CHEMBL884690
(1)
|
0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | CHEMBL666 |
CHEMBL1909212
(2)
|
1 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | CHEMBL666 |
CHEMBL1909211
(2)
|
0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | CHEMBL666 |
CHEMBL1909105
(2)
|
0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | CHEMBL666 |
CHEMBL1909182
(2)
|
0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | CHEMBL666 |
CHEMBL1909173
(2)
|
0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | CHEMBL666 |
CHEMBL1909113
(2)
|
0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | CHEMBL666 |
CHEMBL1909187
(2)
|
0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | CHEMBL666 |
CHEMBL1909168
(2)
|
0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | CHEMBL666 |
CHEMBL1909134
(2)
|
1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL666 |
CHEMBL1909138
(2)
|
0 / 1 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | CHEMBL666 |
CHEMBL1909137
(2)
|
0 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | CHEMBL666 |
CHEMBL1909094
(2)
|
1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | CHEMBL666 |
CHEMBL1909087
(2)
|
0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | CHEMBL666 |
CHEMBL1909213
(2)
|
0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | CHEMBL666 |
CHEMBL1909089
(2)
|
0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | CHEMBL666 |
CHEMBL1909116
(2)
|
1 / 1 |
| P06239 | Tyrosine-protein kinase Lck | Src | CHEMBL666 |
CHEMBL1909206
(2)
|
0 / 1 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | CHEMBL666 |
CHEMBL1909128
(2)
|
0 / 0 |
| P28340 | DNA polymerase delta catalytic subunit | Transferase | CHEMBL666 |
CHEMBL884691
(1)
|
2 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | CHEMBL666 |
CHEMBL830248
(1)
|
1 / 1 |
CTD interaction (6)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| D017245 | 207 |
AKT1
AKT CWS6 PKB PKB-ALPHA PRKBA RAC RAC-ALPHA |
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) | Foscarnet inhibits the reaction [Phosphates results in decreased expression of AKT1 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
23308213
|
| D017245 | 1758 |
DMP1
ARHP ARHR DMP-1 |
dentin matrix acidic phosphoprotein 1 | Foscarnet inhibits the reaction [Phosphates results in increased expression of DMP1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
20185895
|
| D017245 | 5251 |
PHEX
HPDR HPDR1 HYP HYP1 LXHR PEX XLH |
phosphate regulating endopeptidase homolog, X-linked | Foscarnet inhibits the reaction [beta-glycerophosphoric acid results in increased expression of PHEX mRNA] |
decreases reaction
/ increases expression |
mRNA |
18500657
|
| D017245 | 6574 |
SLC20A1
GLVR1 Glvr-1 PIT1 PiT-1 |
solute carrier family 20 (phosphate transporter), member 1 | Foscarnet inhibits the reaction [Phosphates results in increased expression of SLC20A1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
23308213
|
| D017245 | 6574 |
SLC20A1
GLVR1 Glvr-1 PIT1 PiT-1 |
solute carrier family 20 (phosphate transporter), member 1 | Foscarnet results in decreased activity of SLC20A1 protein |
decreases activity
|
protein |
15641067
|
| D017245 | 6575 |
SLC20A2
GLVR-2 GLVR2 IBGC1 IBGC3 MLVAR PIT-2 PIT2 RAM1 |
solute carrier family 20 (phosphate transporter), member 2 | Foscarnet inhibits the reaction [Phosphates results in increased expression of SLC20A2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
23308213
|
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (39)
| OMIM | preferred title | UniProt |
|---|---|---|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| #300615 | Brunner syndrome |
P21397
|
| #612591 | Colorectal cancer, susceptibility to, 10; crcs10 |
P28340
|
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #137800 | Glioma susceptibility 1; glm1 |
P04626
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #615381 | Mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome; mdpl |
P28340
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #159900 | Myoclonic dystonia |
P14416
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #601665 | Obesity |
P32245
|
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (33)
| KEGG | disease name | UniProt |
|---|---|---|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
|
| H00027 | Ovarian cancer |
P04626
(related)
|
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P35354 (related) |
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00025 | Penile cancer |
P14780
(related)
P35354 (related) |
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00021 | Renal cell carcinoma |
Q16790
(marker)
|
Diseases related to CTD interactions
50 disease from interactions of metabolites
| MeSH disease | OMIM | compound | disease name | evidence type |
reference
pmid |
|---|---|---|---|---|---|
| D000141 | D017245 | Acidosis, Renal Tubular |
marker/mechanism
|
8604715
|
|
| D058186 | D017245 | Acute Kidney Injury |
marker/mechanism
therapeutic |
2554731
2840226 2885666 7566623 7802522 8649644 9761526 10231404 10360595 |
|
| D017088 | D017245 | AIDS-Related Opportunistic Infections |
therapeutic
|
7802522
11363124 |
|
| D001008 | D017245 | Anxiety Disorders |
marker/mechanism
|
8384030
|
|
| D003092 | D017245 | Colitis |
therapeutic
|
11362300
|
|
| D003586 | D017245 | Cytomegalovirus Infections |
therapeutic
|
1335467
2560634 2840226 8384030 8781616 9059069 9113493 10231404 10795660 11050094 11362300 |
|
| D017726 | D017245 | Cytomegalovirus Retinitis |
therapeutic
|
7618652
7802522 7949502 8604715 8836823 9740154 11363124 |
|
| D018500 | D017245 | Diabetes Insipidus, Nephrogenic |
marker/mechanism
|
8604715
8836823 |
|
| D064420 | D017245 | Drug-Related Side Effects and Adverse Reactions |
marker/mechanism
|
8806849
|
|
| D004421 | D017245 | Dystonia |
marker/mechanism
|
18356641
|
|
| D020803 | D017245 | Encephalitis, Herpes Simplex |
therapeutic
|
20517946
|
|
| D004830 | D017245 | Epilepsy, Tonic-Clonic |
marker/mechanism
|
7949502
|
|
| D005334 | D017245 | Fever |
marker/mechanism
|
2560634
|
|
| D005921 | D017245 | Glomerulonephritis |
marker/mechanism
|
7618652
10360595 |
|
| D006333 | D017245 | Heart Failure |
marker/mechanism
|
8386905
|
|
| D006402 | D017245 | Hematologic Diseases |
marker/mechanism
|
8806849
|
|
| D006417 | D017245 | Hematuria |
marker/mechanism
|
10231404
10360595 |
|
| D006525 | D017245 | Hepatitis, Viral, Human |
therapeutic
|
9059069
|
|
| D006566 | D017245 | Herpesviridae Infections |
therapeutic
|
7949502
9761526 |
|
| D015658 | D017245 | HIV Infections |
therapeutic
|
7949502
11050094 11362904 |
|
| C538117 | D017245 | Human Herpesvirus 6 encephalitis |
therapeutic
|
18277595
|
|
| D006934 | D017245 | Hypercalcemia |
marker/mechanism
|
9223751
9792397 |
|
| D006996 | D017245 | Hypocalcemia |
marker/mechanism
|
8384030
|
|
| D007008 | D017245 | Hypokalemia |
marker/mechanism
|
1335467
8384030 |
|
| D007010 | D017245 | Hyponatremia |
marker/mechanism
|
18277595
|
|
| D017674 | D017245 | Hypophosphatemia |
marker/mechanism
|
8384030
|
|
| D007015 | D017245 | Hypophosphatemia, Familial |
marker/mechanism
|
8948520
|
|
| D007674 | D017245 | Kidney Diseases |
marker/mechanism
|
8285643
8806849 9113493 18277595 |
|
| D007676 | D017245 | Kidney Failure, Chronic |
marker/mechanism
|
9740173
|
|
| D007683 | D017245 | Kidney Tubular Necrosis, Acute |
marker/mechanism
|
2554731
2840226 |
|
| D008275 | D017245 | Magnesium Deficiency |
marker/mechanism
|
8384030
|
|
| D008582 | D017245 | Meningitis, Aseptic |
therapeutic
|
11197578
|
|
| D009120 | D017245 | Muscle Cramp |
marker/mechanism
|
7803878
|
|
| D009190 | D017245 | Myelodysplastic Syndromes |
therapeutic
|
18277595
|
|
| D009325 | D017245 | Nausea |
marker/mechanism
|
9113493
|
|
| D009395 | D017245 | Nephritis, Interstitial |
marker/mechanism
|
2560634
|
|
| D009404 | D017245 | Nephrotic Syndrome |
marker/mechanism
|
10231404
10360595 |
|
| D009443 | D017245 | Neuritis |
marker/mechanism
|
9761526
|
|
| D009503 | D017245 | Neutropenia |
marker/mechanism
|
7802522
|
|
| D010292 | D017245 | Paresthesia |
marker/mechanism
|
7803878
|
|
| D010409 | D017245 | Penile Diseases |
marker/mechanism
|
9113493
|
|
| D011141 | D017245 | Polyuria |
marker/mechanism
|
8604715
8836823 |
|
| D051437 | D017245 | Renal Insufficiency |
marker/mechanism
|
2560634
9740154 |
|
| D015882 | D017245 | Retinal Necrosis Syndrome, Acute |
therapeutic
|
17406046
|
|
| D012173 | D017245 | Retinitis |
therapeutic
|
1335467
8384030 |
|
| D012640 | D017245 | Seizures |
marker/mechanism
therapeutic |
7802522
7803878 9113493 9517953 |
|
| D013035 | D017245 | Spasm |
marker/mechanism
|
8384030
|
|
| D013746 | D017245 | Tetany |
marker/mechanism
|
7578826
|
|
| D014605 | D017245 | Uveitis |
therapeutic
|
9761526
|
|
| D014883 | D017245 | Water-Electrolyte Imbalance |
marker/mechanism
therapeutic |
7802522
8384030 |