PCIDB

KNApSAcK Metabolite C00001650

Metabolite

KNApSAcK Entry

id C00001650
Name Lappaconitine
CAS RN 32854-75-4
Standard InChI InChI=1S/C32H44N2O8/c1-6-34-16-29(42-28(36)18-9-7-8-10-21(18)33-17(2)35)12-11-25(40-4)31-23(29)14-20(26(31)34)30(37)15-22(39-3)19-13-24(31)32(30,38)27(19)41-5/h7-10,19-20,22-27,37-38H,6,11-16H2,1-5H3,(H,33,35)/t19-,20+,22+,23-,24+,25+,26?,27+,29?,30+,31+,32+/m1/s1
Standard InChI (Main Layer) InChI=1S/C32H44N2O8/c1-6-34-16-29(42-28(36)18-9-7-8-10-21(18)33-17(2)35)12-11-25(40-4)31-23(29)14-20(26(31)34)30(37)15-22(39-3)19-13-24(31)32(30,38)27(19)41-5/h7-10,19-20,22-27,37-38H,6,11-16H2,1-5H3,(H,33,35)

Cluster

Phytochemical cluster No. 10
KCF-S cluster No. 475

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL1592229 CHEMBL1877754 CHEMBL1906763 CHEMBL2112849

KEGG

By LinkDB C08694

CTD

By CAS RN C022150

Human Protein / Gene in interaction

3 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P06280 Alpha-galactosidase A Enzyme CHEMBL1592229 CHEMBL1614217 (1)
1 / 1
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL1592229 CHEMBL1614250 (1)
4 / 3
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL1877754 CHEMBL1794536 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#301500 Fabry disease P06280
#600274 Frontotemporal dementia; ftd P10636
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (4)

KEGG disease name UniProt
H00125 Fabry disease P06280 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)