KNApSAcK Metabolite C00018426
Metabolite
KNApSAcK Entry
| id | C00018426 |
|---|---|
| Name | NSC 613946 / Chrysomycin A |
| CAS RN | 82196-88-1 |
| Standard InChI | InChI=1S/C28H28O9/c1-6-13-9-16-20(18(10-13)34-4)15-11-19(35-5)22-17(29)8-7-14(21(22)23(15)37-27(16)32)24-26(31)28(3,33)25(30)12(2)36-24/h6-12,24-26,29-31,33H,1H2,2-5H3 |
| Standard InChI (Main Layer) | InChI=1S/C28H28O9/c1-6-13-9-16-20(18(10-13)34-4)15-11-19(35-5)22-17(29)8-7-14(21(22)23(15)37-27(16)32)24-26(31)28(3,33)25(30)12(2)36-24/h6-12,24-26,29-31,33H,1H2,2-5H3 |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 1552 |
Link
ChEMBL
| By standard InChI | CHEMBL1728866 |
|---|---|
| By standard InChI Main Layer | CHEMBL1728866 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN | C035075 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Streptomycetaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Streptomyces sp. A-19 | 1883 | Streptomycetaceae | Bacteria |
Human Protein / Gene in interaction
18 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | CHEMBL1728866 |
CHEMBL2114784
(1)
|
1 / 1 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | CHEMBL1728866 |
CHEMBL1794585
(1)
|
0 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | CHEMBL1728866 |
CHEMBL2354282
(1)
|
4 / 2 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | CHEMBL1728866 |
CHEMBL1794495
(1)
|
2 / 2 |
| P39748 | Flap endonuclease 1 | Enzyme | CHEMBL1728866 |
CHEMBL1794486
(1)
|
0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | CHEMBL1728866 |
CHEMBL1794584
(1)
|
2 / 0 |
| O75496 | Geminin | Unclassified protein | CHEMBL1728866 |
CHEMBL2114843
(1)
CHEMBL2114780
(1)
|
0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | CHEMBL1728866 |
CHEMBL2114788
(1)
|
0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | CHEMBL1728866 |
CHEMBL1794569
(1)
|
1 / 1 |
| P11308 | Transcriptional regulator ERG | Unclassified protein | CHEMBL1728866 |
CHEMBL2114924
(1)
|
1 / 2 |
| Q9UNA4 | DNA polymerase iota | Enzyme | CHEMBL1728866 |
CHEMBL1794483
(1)
|
0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | CHEMBL1728866 |
CHEMBL1738184
(1)
|
0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | CHEMBL1728866 |
CHEMBL1794536
(1)
|
0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | CHEMBL1728866 |
CHEMBL1964002
(1)
CHEMBL2354311
(1)
|
1 / 0 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | CHEMBL1728866 |
CHEMBL2114913
(1)
|
0 / 3 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | CHEMBL1728866 |
CHEMBL2114796
(1)
|
2 / 1 |
| Q06710 | Paired box protein Pax-8 | Unclassified protein | CHEMBL1728866 |
CHEMBL2354301
(1)
|
1 / 2 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | CHEMBL1728866 |
CHEMBL2354287
(1)
|
1 / 1 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (15)
| OMIM | preferred title | UniProt |
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #114500 | Colorectal cancer; crc |
P84022
Q14191 |
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #612219 | Ewing sarcoma; es |
P11308
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #218700 | Hypothyroidism, congenital, nongoitrous, 2; chng2 |
Q06710
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (14)
| KEGG | disease name | UniProt |
|---|---|---|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
Q06710 (related) |
| H00024 | Prostate cancer |
P11308
(related)
|
| H00035 | Ewing's sarcoma |
P11308
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00032 | Thyroid cancer |
Q06710
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|