PCIDB

Streptomyces sp. A-19

Species

KNApSAcK Entry

Organism name Streptomyces sp. A-19
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces
Linked NCBI taxonomy ID 1883
Linked level genus

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00018426 External link 512 NSC 613946
/ Chrysomycin A
CHEMBL1728866
C035075
18 / 15 / 14 No. 1552

Human Protein / Gene in interactions

18 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00018426 1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00018426 0 / 0
P37840 Alpha-synuclein Unclassified protein C00018426 4 / 2
P17405 Sphingomyelin phosphodiesterase Enzyme C00018426 2 / 2
P39748 Flap endonuclease 1 Enzyme C00018426 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00018426 2 / 0
O75496 Geminin Unclassified protein C00018426 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00018426 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00018426 1 / 1
P11308 Transcriptional regulator ERG Unclassified protein C00018426 1 / 2
Q9UNA4 DNA polymerase iota Enzyme C00018426 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00018426 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00018426 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00018426 1 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00018426 0 / 3
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00018426 2 / 1
Q06710 Paired box protein Pax-8 Unclassified protein C00018426 1 / 2
Q13148 TAR DNA-binding protein 43 Unclassified protein C00018426 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#114500 Colorectal cancer; crc P84022
Q14191
#127750 Dementia, lewy body; dlb P37840
#612219 Ewing sarcoma; es P11308
#137800 Glioma susceptibility 1; glm1 O75874
#218700 Hypothyroidism, congenital, nongoitrous, 2; chng2 Q06710
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (14)

KEGG name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
Q06710 (related)
H00024 Prostate cancer P11308 (related)
H00035 Ewing's sarcoma P11308 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00032 Thyroid cancer Q06710 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)