KNApSAcK Metabolite C00018670
Metabolite
KNApSAcK Entry
| id | C00018670 |
|---|---|
| Name | U 10071 / Tubercidine / Sparsamycin A / 7-Deazaadenosine / Antibiotic XK 101-1 |
| CAS RN | 69-33-0 |
| Standard InChI | InChI=1S/C11H14N4O4/c12-9-5-1-2-15(10(5)14-4-13-9)11-8(18)7(17)6(3-16)19-11/h1-2,4,6-8,11,16-18H,3H2,(H2,12,13,14)/t6-,7+,8?,11-/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C11H14N4O4/c12-9-5-1-2-15(10(5)14-4-13-9)11-8(18)7(17)6(3-16)19-11/h1-2,4,6-8,11,16-18H,3H2,(H2,12,13,14) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 1761 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer | CHEMBL267099 CHEMBL599189 CHEMBL2093914 CHEMBL2311082 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN | D014372 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Streptomycetaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Streptomyces tubercidicus | 47759 | Streptomycetaceae | Bacteria |
Human Protein / Gene in interaction
12 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | CHEMBL267099 |
CHEMBL2114784
(1)
|
1 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | CHEMBL267099 |
CHEMBL1794584
(1)
|
2 / 0 |
| O75496 | Geminin | Unclassified protein | CHEMBL267099 |
CHEMBL2114843
(1)
CHEMBL2114780
(1)
|
0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | CHEMBL267099 |
CHEMBL2114788
(1)
|
0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | CHEMBL267099 |
CHEMBL2114817
(1)
|
7 / 3 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | CHEMBL267099 |
CHEMBL1794401
(1)
|
0 / 0 |
| P55263 | Adenosine kinase | Enzyme | CHEMBL267099 |
CHEMBL642225
(1)
|
1 / 0 |
| P00491 | Purine nucleoside phosphorylase | Enzyme | CHEMBL599189 |
CHEMBL1072376
(1)
|
1 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | CHEMBL267099 |
CHEMBL1794483
(1)
|
0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | CHEMBL267099 |
CHEMBL1738184
(1)
|
0 / 0 |
| Q53EL6 | Programmed cell death protein 4 | Unclassified protein | CHEMBL267099 |
CHEMBL1913571
(1)
CHEMBL1913572
(1)
|
0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | CHEMBL267099 |
CHEMBL2354311
(1)
|
1 / 0 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (13)
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #614300 | Hypermethioninemia due to adenosine kinase deficiency |
P55263
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #613179 | Purine nucleoside phosphorylase deficiency |
P00491
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
KEGG DISEASE (5)
| KEGG | disease name | UniProt |
|---|---|---|
| H00093 | Combined immunodeficiencies (CIDs) |
P00491
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|