KCF-S cluster No. 1761 (6 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (6)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	2
Liliopsida	2
eudicotyledons	1

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Cumulative family count

class name	count
Streptomycetaceae	3
Enterobacteriaceae	2
Phyllanthaceae	1
Hymenochaetaceae	1
Euphorbiaceae	1
Agaricaceae	1
Crassulaceae	1
Subergorgiidae	1
Poaceae	1
Amaryllidaceae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (6)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00001496	Crotonoside	CHEMBL296017 CHEMBL609077 CHEMBL1688963 CHEMBL1741830	C008184	10 / 2 / 3
C00018365	Oxanosine / NSC 359452	CHEMBL1969011	C032886
C00018670	U 10071 / Tubercidine / Sparsamycin A / 7-Deazaadenosine / Antibiotic XK 101-1	CHEMBL267099 CHEMBL599189 CHEMBL2093914 CHEMBL2311082	D014372	12 / 13 / 5
C00018685	Nebularine / Purinosine / Ribosylpurine / Purine riboside / Purine-9-beta-D-ribofuranoside / 9-beta-D-Ribofuranosyl-9H-purine	CHEMBL1399702 CHEMBL1476759	C005248	15 / 30 / 55
C00019679	Guanosine / 9-beta-D-Ribofuranosylguanine	CHEMBL278434 CHEMBL375655 CHEMBL240933 CHEMBL607672 CHEMBL2021379 CHEMBL2093064	D006151	5 / 4 / 4	3 / 0
C00019692	Inosine	CHEMBL9850 CHEMBL1556 CHEMBL1213651 CHEMBL2092757	D007288	13 / 14 / 5	2 / 2

Human Protein / Gene in interactions

41 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001496 C00018685	1 / 0
P23526	Adenosylhomocysteinase	Enzyme	C00019679 C00019692	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00018670 C00019692	1 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00018685 C00019692	4 / 1
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00018670 C00019692	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00018670 C00019692	1 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00001496 C00018670	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001496 C00018685	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001496 C00018685	1 / 1
P00491	Purine nucleoside phosphorylase	Enzyme	C00018670 C00019692	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001496 C00018685	0 / 0
O75496	Geminin	Unclassified protein	C00018670 C00019692	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00001496 C00018685	0 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00018670 C00019692	2 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00018670	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00019692	0 / 0
P68871	Hemoglobin subunit beta	Secreted protein	C00018685	4 / 4
P54132	Bloom syndrome protein	Enzyme	C00018685	1 / 2
P04183	Thymidine kinase, cytosolic	Enzyme	C00019679	0 / 1
P35348	Alpha-1A adrenergic receptor	Adrenergic receptor	C00018685	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00019692	1 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00018670	7 / 3
P83916	Chromobox protein homolog 1	Unclassified protein	C00018670	0 / 0
P55263	Adenosine kinase	Enzyme	C00018670	1 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00019692	3 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00018685	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00018685	0 / 0
P00813	Adenosine deaminase	Hydrolase	C00018685	1 / 1
P02545	Prelamin-A/C	Unclassified protein	C00018685	11 / 10
O15245	Solute carrier family 22 member 1	Drug uniporter	C00019692	0 / 0
O00142	Thymidine kinase 2, mitochondrial	Enzyme	C00019679	1 / 1
P00492	Hypoxanthine-guanine phosphoribosyltransferase	Enzyme	C00019679	2 / 1
Q6DHV7	Adenosine deaminase-like protein	Enzyme	C00001496	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00019692	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00019679	0 / 0
Q53EL6	Programmed cell death protein 4	Unclassified protein	C00018670	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00018685	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00018685	7 / 37
P29274	Adenosine receptor A2a	Adenosine receptor	C00001496	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00001496	0 / 0
P29275	Adenosine receptor A2b	Adenosine receptor	C00001496	0 / 0

5 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00019679
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00019679
55315	SLC29A3, ENT3, HCLAP, HJCD, PHID	solute carrier family 29 (equilibrative nucleoside transporter), member 3	C00019679
100	ADA	adenosine deaminase (EC:3.5.4.4)	C00019692
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00019692

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions