KNApSAcK Metabolite C00019679
Metabolite
KNApSAcK Entry
| id | C00019679 |
|---|---|
| Name | Guanosine / 9-beta-D-Ribofuranosylguanine |
| CAS RN | 118-00-3 |
| Standard InChI | InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5?,6+,9-/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 1761 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer | CHEMBL278434 CHEMBL375655 CHEMBL240933 CHEMBL607672 CHEMBL2021379 CHEMBL2093064 |
KEGG
| By LinkDB | C00387 |
|---|
CTD
| By CAS RN | D006151 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| rosids | 1 |
| eudicotyledons | 1 |
| Liliopsida | 1 |
Family
| family name | count |
|---|---|
| Enterobacteriaceae | 1 |
| Phyllanthaceae | 1 |
| Crassulaceae | 1 |
| Subergorgiidae | 1 |
| Poaceae | 1 |
List (5)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Escherichia coli | 562 | Enterobacteriaceae | Bacteria | |
| Sauropus androgynus | 283133 | Phyllanthaceae | rosids | Viridiplantae |
| Sinocrassula indica | 91157 | Crassulaceae | eudicotyledons | Viridiplantae |
| Subergorgia suberosa | 767284 | Subergorgiidae | Metazoa | |
| Zea mays L. | 4577 | Poaceae | Liliopsida | Viridiplantae |
Human Protein / Gene in interaction
5 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P23526 | Adenosylhomocysteinase | Enzyme | CHEMBL375655 |
CHEMBL807542
(1)
CHEMBL803087
(1)
CHEMBL883376 (1) |
1 / 1 |
| P00492 | Hypoxanthine-guanine phosphoribosyltransferase | Enzyme | CHEMBL375655 |
CHEMBL698187
(1)
|
2 / 1 |
| P04183 | Thymidine kinase, cytosolic | Enzyme | CHEMBL240933 |
CHEMBL886766
(1)
|
0 / 1 |
| O00142 | Thymidine kinase 2, mitochondrial | Enzyme | CHEMBL240933 |
CHEMBL886767
(1)
|
1 / 1 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | CHEMBL375655 |
CHEMBL1613829
(1)
|
0 / 0 |
CTD interaction (3)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| D006151 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | Guanosine results in increased phosphorylation of and results in increased activity of MAPK1 protein |
increases activity
/ increases phosphorylation |
protein |
18456249
|
| D006151 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | Guanosine results in increased phosphorylation of and results in increased activity of MAPK3 protein |
increases activity
/ increases phosphorylation |
protein |
18456249
|
| D006151 | 55315 |
SLC29A3
ENT3 HCLAP HJCD PHID |
solute carrier family 29 (equilibrative nucleoside transporter), member 3 | SLC29A3 protein affects the transport of Guanosine |
affects transport
|
protein |
19164483
|