Species

KNApSAcK Entry

Organism name Sauropus androgynus
Genus Sauropus
Family Phyllanthaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Sauropus androgynus
Linked NCBI taxonomy ID 283133
Linked level species

Family

Family in NCBI taxonomy Phyllanthaceae
ID 233880

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000723 External link 512 Liriodendrin
/ Acanthoside D
/ (+)-Syringaresinol di-O-beta-glucopyranoside
CHEMBL446836
CHEMBL505393
2 / 2 / 2 No. 152
C00032855 External link 512 Corchoionoside C
/ (+)-Corchoionoside C
CHEMBL444196
CHEMBL482383
CHEMBL520291
CHEMBL465921
No. 225
C00019679 External link 512 Guanosine
/ 9-beta-D-Ribofuranosylguanine
CHEMBL278434
CHEMBL375655
CHEMBL240933
CHEMBL607672
CHEMBL2021379
CHEMBL2093064
D006151
5 / 4 / 4 3 / 0 No. 1761

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P23526 Adenosylhomocysteinase Enzyme C00019679 1 / 1
P00492 Hypoxanthine-guanine phosphoribosyltransferase Enzyme C00019679 2 / 1
P04183 Thymidine kinase, cytosolic Enzyme C00019679 0 / 1
P17405 Sphingomyelin phosphodiesterase Enzyme C00000723 2 / 2
O75496 Geminin Unclassified protein C00000723 0 / 0
O00142 Thymidine kinase 2, mitochondrial Enzyme C00019679 1 / 1
P46063 ATP-dependent DNA helicase Q1 Enzyme C00019679 0 / 0

3 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00019679
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00019679
55315 SLC29A3, ENT3, HCLAP, HJCD, PHID solute carrier family 29 (equilibrative nucleoside transporter), member 3 C00019679

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#613752 Hypermethioninemia with s-adenosylhomocysteine hydrolase deficiency P23526
#300323 Kelley-seegmiller syndrome P00492
#300322 Lesch-nyhan syndrome; lns P00492
#609560 Mitochondrial dna depletion syndrome 2 (myopathic type); mtdps2 O00142
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405

KEGG DISEASE (6)

KEGG name UniProt
H00469 Mitochondrial DNA depletion syndrome (MDS) O00142 (related)
H00194 Lesch-Nyhan syndrome P00492 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04183 (marker)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00184 Hypermethioninemia P23526 (related)