KNApSAcK Metabolite C00018851
Metabolite
KNApSAcK Entry
| id | C00018851 |
|---|---|
| Name | M 4365A2 / Rosamicin / Sch 14947 / NSC 175150 / Rosaramicin / Juvenimicin A3 / Antibiotic 67-694 / Antibiotic T 1124C / Antibiotic M 4365A2 / 4'-Deoxycirramycin A1 |
| CAS RN | 35834-26-5 |
| Standard InChI | InChI=1S/C31H51NO9/c1-9-25-20(5)29-31(6,41-29)12-10-23(34)17(2)14-21(11-13-33)28(19(4)24(35)16-26(36)39-25)40-30-27(37)22(32(7)8)15-18(3)38-30/h10,12-13,17-22,24-25,27-30,35,37H,9,11,14-16H2,1-8H3/b12-10+ |
| Standard InChI (Main Layer) | InChI=1S/C31H51NO9/c1-9-25-20(5)29-31(6,41-29)12-10-23(34)17(2)14-21(11-13-33)28(19(4)24(35)16-26(36)39-25)40-30-27(37)22(32(7)8)15-18(3)38-30/h10,12-13,17-22,24-25,27-30,35,37H,9,11,14-16H2,1-8H3 |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 1715 |
Link
ChEMBL
| By standard InChI | CHEMBL1966403 |
|---|---|
| By standard InChI Main Layer | CHEMBL8965 CHEMBL26194 CHEMBL1546091 CHEMBL1966403 CHEMBL2357105 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN | C060286 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Micromonosporaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Micromonospora rosaria NRRL No. 3718 | 1873 | Micromonosporaceae | Bacteria |
Human Protein / Gene in interaction
4 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | CHEMBL1546091 |
CHEMBL1614153
(1)
|
1 / 4 |
| O75496 | Geminin | Unclassified protein | CHEMBL26194 |
CHEMBL2114780
(1)
|
0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | CHEMBL1546091 |
CHEMBL1738588
(1)
|
0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | CHEMBL1546091 |
CHEMBL1614421
(1)
|
4 / 3 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (5)
| OMIM | preferred title | UniProt |
|---|---|---|
| #208900 | Ataxia-telangiectasia; at |
Q13315
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
KEGG DISEASE (7)
| KEGG | disease name | UniProt |
|---|---|---|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
Q13315
(related)
|
| H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
| H00094 | DNA repair defects |
Q13315
(related)
|
| H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|