| class name | count |
|---|
| class name | count |
|---|---|
| Micromonosporaceae | 5 |
| Streptomycetaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00017607
|
6108A1
/ Antibiotic 6108A1 |
C066089
|
|
|||
|
C00017608
|
6108B
/ Antibiotic 6108B |
C066090
|
|
|||
|
C00017609
|
6108C
/ Antibiotic 6108C |
C066091
|
|
|||
|
C00017610
|
Antibiotic 6108D
|
C066088
|
|
|||
|
C00018762
|
NSC 246129
/ Cirramycin A1 / Antibiotic B 58941B |
CHEMBL1976094
|
C059005
|
|
||
|
C00018851
|
M 4365A2
/ Rosamicin / Sch 14947 / NSC 175150 / Rosaramicin / Juvenimicin A3 / Antibiotic 67-694 / Antibiotic T 1124C / Antibiotic M 4365A2 / 4'-Deoxycirramycin A1 |
CHEMBL8965
CHEMBL26194 CHEMBL1546091 CHEMBL1966403 CHEMBL2357105 |
C060286
|
4 / 5 / 7 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00018851 | 1 / 4 |
| O75496 | Geminin | Unclassified protein | C00018851 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00018851 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00018851 | 4 / 3 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #208900 | Ataxia-telangiectasia; at |
Q13315
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
Q13315
(related)
|
| H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
| H00094 | DNA repair defects |
Q13315
(related)
|
| H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|