PCIDB

KNApSAcK Metabolite C00001915

Index

Metabolite

Species

Human Protein
/ Gene in interactions

Related Diseases

Metabolite

KNApSAcK Entry

id	C00001915
Name	Salsolinol / (-)-Salsolinol
CAS RN	27740-96-1
Standard InChI	InChI=1S/C10H13NO2/c1-6-8-5-10(13)9(12)4-7(8)2-3-11-6/h4-6,11-13H,2-3H2,1H3/t6-/m0/s1
Standard InChI (Main Layer)	InChI=1S/C10H13NO2/c1-6-8-5-10(13)9(12)4-7(8)2-3-11-6/h4-6,11-13H,2-3H2,1H3

Cluster

Phytochemical cluster	No. 4
KCF-S cluster	No. 2962

Link

ChEMBL

By standard InChI	CHEMBL1195032
By standard InChI Main Layer	CHEMBL416732 CHEMBL1193327 CHEMBL1195032

KEGG

By LinkDB	C09642

CTD

By CAS RN

Species

Summary

Plant class

class name	count
Liliopsida	1
rosids	1
Magnoliophyta	1
eudicotyledons	1

Family

family name	count
Musaceae	1
Malvaceae	1
Aristolochiaceae	1
Papaveraceae	1

List (4)

* NCBI

KNApSAcK organism	*ID	*family	*plant class	*kingdom
Aristolochia arcuata	158533	Aristolochiaceae	Magnoliophyta	Viridiplantae
Musa x paradisiaca	89151	Musaceae	Liliopsida	Viridiplantae
Papaver somniferum	3469	Papaveraceae	eudicotyledons	Viridiplantae
Theobroma cacao	3641	Malvaceae	rosids	Viridiplantae

Human Protein / Gene in interaction

14 ChEMBL Protein in interactions

accession	description	class description	compound	assay ID (# of activities)	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	CHEMBL1195032	CHEMBL1741321 (1)	1 / 0
Q99700	Ataxin-2	Unclassified protein	CHEMBL1195032	CHEMBL2114784 (1)	1 / 1
P16473	Thyrotropin receptor	Glycohormone receptor	CHEMBL1195032	CHEMBL1614361 (1)	3 / 2
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	CHEMBL1195032	CHEMBL1614027 (1) CHEMBL1741325 (1)	0 / 1
P14416	D(2) dopamine receptor	Dopamine receptor	CHEMBL416732	CHEMBL670395 (1) CHEMBL848511 (1)	2 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	CHEMBL1195032	CHEMBL1614456 (1) CHEMBL1613803 (1)	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	CHEMBL416732	CHEMBL671251 (1) CHEMBL848511 (1)	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	CHEMBL1195032	CHEMBL1741322 (1)	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	CHEMBL1195032	CHEMBL1613910 (1) CHEMBL1614227 (1)	3 / 3
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	CHEMBL1195032	CHEMBL1741323 (1)	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	CHEMBL1195032	CHEMBL1741324 (1)	0 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	CHEMBL1195032	CHEMBL1614211 (1)	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	CHEMBL1195032	CHEMBL1613914 (1)	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	CHEMBL1195032	CHEMBL1738442 (1)	0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM	preferred title	UniProt
#300438	17-beta-hydroxysteroid dehydrogenase x deficiency	Q99714
#103780	Alcohol dependence	P14416
#609535	Drug metabolism, poor, cyp2c19-related	P33261
#608902	Drug metabolism, poor, cyp2d6-related	P10635
#603373	Hyperthyroidism, familial gestational	P16473
#609152	Hyperthyroidism, nonautoimmune	P16473
#275200	Hypothyroidism, congenital, nongoitrous, 1; chng1	P16473
#300705	Mental retardation, x-linked 17; mrx17	Q99714
#300220	Mental retardation, x-linked, syndromic 10; mrxs10	Q99714
#159900	Myoclonic dystonia	P14416
#183090	Spinocerebellar ataxia 2; sca2	Q99700

KEGG DISEASE (9)

KEGG	disease name	UniProt
H00036	Osteosarcoma	P08684 (marker)
H01205	Coumarin resistance	P11712 (related)
H00250	Congenital nongoitrous hypothyroidism (CHNG)	P16473 (related)
H01269	Congenital hyperthyroidism	P16473 (related)
H01171	Poor drug metabolism (PM)	P33261 (related)
H00063	Spinocerebellar ataxia (SCA)	Q99700 (related)
H00480	Non-syndromic X-linked mental retardation	Q99714 (related)
H00658	Syndromic X-linked mental retardation	Q99714 (related)
H00925	2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency	Q99714 (related)