KNApSAcK Metabolite C00019577
Metabolite
KNApSAcK Entry
| id | C00019577 |
|---|---|
| Name | D-Glutamate / D-Glutamic acid / D-Glutaminic acid / D-2-Aminoglutaric acid |
| CAS RN | 6893-26-1 |
| Standard InChI | InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 2641 |
Link
ChEMBL
| By standard InChI | CHEMBL76232 |
|---|---|
| By standard InChI Main Layer | CHEMBL76232 CHEMBL575060 |
KEGG
| By LinkDB | C00217 |
|---|
CTD
| By CAS RN |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Enterobacteriaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Escherichia coli | 562 | Enterobacteriaceae | Bacteria |
Human Protein / Gene in interaction
37 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | CHEMBL76232 CHEMBL575060 |
CHEMBL1614110
(1)
CHEMBL1741321
(3)
|
1 / 0 |
| P48058 | Glutamate receptor 4 | NS | CHEMBL76232 CHEMBL575060 |
CHEMBL878454
(1)
CHEMBL696661
(1)
CHEMBL696662 (1) CHEMBL895668 (2) |
0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | CHEMBL575060 |
CHEMBL1794499
(2)
|
2 / 0 |
| P14618 | Pyruvate kinase PKM | Enzyme | CHEMBL76232 |
CHEMBL1614177
(1)
CHEMBL1614265
(1)
|
0 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | CHEMBL575060 |
CHEMBL881969
(1)
|
0 / 0 |
| Q13003 | Glutamate receptor ionotropic, kainate 3 | NS | CHEMBL76232 CHEMBL575060 |
CHEMBL701553
(1)
CHEMBL701554
(1)
|
0 / 0 |
| O00222 | Metabotropic glutamate receptor 8 | Metabotropic glutamate receptor | CHEMBL575060 |
CHEMBL712473
(1)
CHEMBL828593
(1)
|
0 / 0 |
| P43004 | Excitatory amino acid transporter 2 | Aspartate and glutamate Na-symporter | CHEMBL575060 |
CHEMBL859748
(2)
CHEMBL907706
(2)
CHEMBL1016591 (2) |
0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | CHEMBL575060 |
CHEMBL1738600
(1)
|
0 / 0 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | CHEMBL575060 |
CHEMBL1613894
(1)
|
0 / 1 |
| P42261 | Glutamate receptor 1 | NS | CHEMBL76232 CHEMBL575060 |
CHEMBL878883
(1)
CHEMBL701240
(1)
CHEMBL701241 (1) CHEMBL895662 (2) CHEMBL1105503 (1) CHEMBL1117247 (1) |
0 / 0 |
| Q16478 | Glutamate receptor ionotropic, kainate 5 | NS | CHEMBL76232 CHEMBL575060 |
CHEMBL874133
(1)
CHEMBL698076
(1)
CHEMBL701557 (1) |
0 / 0 |
| Q13002 | Glutamate receptor ionotropic, kainate 2 | NS | CHEMBL76232 CHEMBL575060 |
CHEMBL683696
(1)
CHEMBL685948
(1)
CHEMBL884244 (1) CHEMBL699990 (1) CHEMBL701169 (1) CHEMBL701332 (1) |
1 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | CHEMBL76232 CHEMBL575060 |
CHEMBL1741325
(3)
|
0 / 1 |
| Q14831 | Metabotropic glutamate receptor 7 | Metabotropic glutamate receptor | CHEMBL76232 CHEMBL575060 |
CHEMBL712391
(1)
CHEMBL712460
(1)
CHEMBL712461 (1) CHEMBL863304 (1) CHEMBL892221 (1) |
0 / 0 |
| P43005 | Excitatory amino acid transporter 3 | Aspartate, glutamate and cysteine Na-symporter | CHEMBL575060 |
CHEMBL859749
(2)
CHEMBL907707
(2)
CHEMBL1013069 (2) |
1 / 1 |
| P39086 | Glutamate receptor ionotropic, kainate 1 | NS | CHEMBL76232 CHEMBL575060 |
CHEMBL683542
(1)
CHEMBL683695
(1)
CHEMBL697422 (1) CHEMBL697426 (1) CHEMBL698072 (1) CHEMBL698073 (1) CHEMBL865002 (1) |
0 / 0 |
| Q14416 | Metabotropic glutamate receptor 2 | Metabotropic glutamate receptor | CHEMBL76232 CHEMBL575060 |
CHEMBL877752
(1)
CHEMBL717757
(1)
CHEMBL718221 (1) CHEMBL718222 (1) CHEMBL713617 (2) CHEMBL713618 (1) CHEMBL820339 (1) CHEMBL852485 (1) CHEMBL863297 (1) CHEMBL892218 (1) CHEMBL895145 (1) CHEMBL1018993 (1) CHEMBL1671545 (1) |
0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | CHEMBL76232 |
CHEMBL1794467
(1)
|
0 / 0 |
| P42263 | Glutamate receptor 3 | NS | CHEMBL575060 |
CHEMBL895666
(2)
CHEMBL1105505
(1)
CHEMBL1117249 (1) |
1 / 1 |
| O15303 | Metabotropic glutamate receptor 6 | Metabotropic glutamate receptor | CHEMBL76232 CHEMBL575060 |
CHEMBL718128
(1)
CHEMBL718130
(1)
CHEMBL712215 (1) CHEMBL712387 (1) CHEMBL712388 (1) CHEMBL1052814 (1) |
1 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | CHEMBL76232 CHEMBL575060 |
CHEMBL1741322
(3)
|
0 / 0 |
| P00390 | Glutathione reductase, mitochondrial | Oxidoreductase | CHEMBL575060 |
CHEMBL1825434
(1)
CHEMBL1825435
(1)
|
0 / 0 |
| Q04609 | Glutamate carboxypeptidase 2 | M28B | CHEMBL575060 |
CHEMBL888570
(1)
|
0 / 0 |
| Q14833 | Metabotropic glutamate receptor 4 | Metabotropic glutamate receptor | CHEMBL76232 CHEMBL575060 |
CHEMBL714803
(1)
CHEMBL884506
(1)
CHEMBL716502 (1) CHEMBL714668 (1) CHEMBL714003 (1) CHEMBL714009 (2) CHEMBL852486 (1) CHEMBL895143 (1) CHEMBL1018994 (1) |
0 / 0 |
| Q13255 | Metabotropic glutamate receptor 1 | Metabotropic glutamate receptor | CHEMBL76232 CHEMBL575060 |
CHEMBL709770
(1)
CHEMBL709773
(1)
CHEMBL719076 (1) CHEMBL717333 (2) CHEMBL717334 (1) CHEMBL717930 (1) CHEMBL851587 (1) CHEMBL895144 (1) CHEMBL1018991 (1) |
1 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | CHEMBL76232 CHEMBL575060 |
CHEMBL1741323
(3)
|
1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL76232 CHEMBL575060 |
CHEMBL1614108
(1)
CHEMBL1613886
(1)
CHEMBL1741324 (3) |
0 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | CHEMBL76232 |
CHEMBL1614211
(1)
|
0 / 0 |
| Q14832 | Metabotropic glutamate receptor 3 | Metabotropic glutamate receptor | CHEMBL76232 CHEMBL575060 |
CHEMBL714446
(1)
CHEMBL717238
(1)
CHEMBL818777 (1) |
0 / 0 |
| P42262 | Glutamate receptor 2 | NS | CHEMBL76232 CHEMBL575060 |
CHEMBL696974
(1)
CHEMBL696975
(1)
CHEMBL696976 (1) CHEMBL895664 (2) CHEMBL1105504 (1) CHEMBL1117248 (1) CHEMBL1104014 (2) CHEMBL1226126 (1) |
0 / 0 |
| P41594 | Metabotropic glutamate receptor 5 | Metabotropic glutamate receptor | CHEMBL76232 CHEMBL575060 |
CHEMBL711712
(1)
CHEMBL709916
(1)
CHEMBL715721 (1) CHEMBL715723 (1) CHEMBL895146 (1) CHEMBL1018992 (1) CHEMBL1052813 (1) |
0 / 0 |
| P43003 | Excitatory amino acid transporter 1 | Aspartate and glutamate Na-symporter | CHEMBL575060 |
CHEMBL859747
(2)
CHEMBL907705
(2)
CHEMBL1016590 (2) |
1 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | CHEMBL575060 |
CHEMBL1738442
(1)
|
0 / 0 |
| Q05BR4 | SLC16A10 protein | Unclassified protein | CHEMBL76232 |
CHEMBL2076232
(1)
|
0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | CHEMBL575060 |
CHEMBL2114738
(1)
|
0 / 0 |
| Q9C0B1 | Alpha-ketoglutarate-dependent dioxygenase FTO | Unclassified protein | CHEMBL76232 CHEMBL575060 |
CHEMBL2344107
(2)
|
1 / 2 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (11)
| OMIM | preferred title | UniProt |
|---|---|---|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #612656 | Episodic ataxia, type 6; ea6 |
P43003
|
| #612938 | Growth retardation, developmental delay, coarse facies, and early death; gdfd |
Q9C0B1
|
| #611092 | Mental retardation, autosomal recessive 6; mrt6 |
Q13002
|
| #300699 | Mental retardation, x-linked, syndromic, wu type; mrxsw |
P42263
|
| #257270 | Night blindness, congenital stationary, type 1b; csnb1b |
O15303
|
| #615232 | Schizophrenia 18; sczd18 |
P43005
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #614831 | Spinocerebellar ataxia, autosomal recessive 13; scar13 |
Q13255
|
KEGG DISEASE (11)
| KEGG | disease name | UniProt |
|---|---|---|
| H00787 | Congenital stationary night blindness (CSNB) |
O15303
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00577 | Syndromic X-linked mental retardation with epilepsy or seizures |
P42263
(related)
|
| H00749 | Episodic ataxias |
P43003
(related)
|
| H00911 | Dicarboxylic aminoaciduria |
P43005
(related)
|
| H00768 | Nonsyndromic autosomal recessive mental retardation (NS-ARMR) |
Q13002
(related)
|
| H00409 | Type II diabetes mellitus |
Q9C0B1
(related)
|
| H00926 | Growth retardation, developmental delay, coarse facies, and early death |
Q9C0B1
(related)
|