KNApSAcK Metabolite C00019686
Metabolite
KNApSAcK Entry
| id | C00019686 |
|---|---|
| Name | FMN / Flavin mononucleotide / Riboflavine 5'-phosphate |
| CAS RN | 146-17-8 |
| Standard InChI | InChI=1S/C17H21N4O9P/c1-7-3-9-10(4-8(7)2)21(15-13(18-9)16(25)20-17(26)19-15)5-11(22)14(24)12(23)6-30-31(27,28)29/h3-4,11-12,14,22-24H,5-6H2,1-2H3,(H,20,25,26)(H2,27,28,29)/t11-,12+,14-/m0/s1 |
| Standard InChI (Main Layer) | InChI=1S/C17H21N4O9P/c1-7-3-9-10(4-8(7)2)21(15-13(18-9)16(25)20-17(26)19-15)5-11(22)14(24)12(23)6-30-31(27,28)29/h3-4,11-12,14,22-24H,5-6H2,1-2H3,(H,20,25,26)(H2,27,28,29) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 2559 |
Link
ChEMBL
| By standard InChI | CHEMBL1201794 |
|---|---|
| By standard InChI Main Layer | CHEMBL365423 CHEMBL1201794 |
KEGG
| By LinkDB | C00061 |
|---|
CTD
| By CAS RN | D005486 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Enterobacteriaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Escherichia coli | 562 | Enterobacteriaceae | Bacteria |
Human Protein / Gene in interaction
10 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P02545 | Prelamin-A/C | Unclassified protein | CHEMBL365423 |
CHEMBL1614544
(1)
|
11 / 10 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | CHEMBL365423 |
CHEMBL1738606
(1)
|
0 / 0 |
| P42858 | Huntingtin | Unclassified protein | CHEMBL365423 |
CHEMBL1613918
(1)
|
1 / 1 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | CHEMBL365423 |
CHEMBL1614410
(1)
CHEMBL1614531
(1)
|
1 / 3 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | CHEMBL365423 |
CHEMBL1794467
(1)
|
0 / 0 |
| P04818 | Thymidylate synthase | Transferase | CHEMBL1201794 |
CHEMBL1029822
(1)
|
0 / 0 |
| P00374 | Dihydrofolate reductase | Oxidoreductase | CHEMBL1201794 |
CHEMBL1029821
(1)
|
1 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | CHEMBL365423 |
CHEMBL1614250
(1)
CHEMBL1614421
(1)
|
4 / 3 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | CHEMBL365423 |
CHEMBL1738442
(1)
|
0 / 0 |
| O00255 | Menin | Unclassified protein | CHEMBL365423 |
CHEMBL1614531
(1)
|
2 / 5 |
CTD interaction (1)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| D005486 | 55312 |
RFK
RIFK |
riboflavin kinase (EC:2.7.1.26) | RFK protein results in increased abundance of Flavin Mononucleotide |
increases abundance
|
protein |
21308351
|
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (20)
| OMIM | preferred title | UniProt |
|---|---|---|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #143100 | Huntington disease; hd |
P42858
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613839 | Megaloblastic anemia due to dihydrofolate reductase deficiency |
P00374
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
KEGG DISEASE (22)
| KEGG | disease name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01197 | Dihydrofolate reductase (DHFR) deficiency |
P00374
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|