| class name | count |
|---|
| class name | count |
|---|---|
| Enterobacteriaceae | 2 |
| Streptomycetaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00017984
|
Roseoflavin
/ Roseoflavine / 8-Dimethylaminoriboflavin |
C009191
|
|
|||
|
C00019640
|
6,7-Dimethyl-8-ribityllumazine
|
|
||||
|
C00019686
|
FMN
/ Flavin mononucleotide / Riboflavine 5'-phosphate |
CHEMBL365423
CHEMBL1201794 |
D005486
|
10 / 20 / 22 | 1 / 0 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P02545 | Prelamin-A/C | Unclassified protein | C00019686 | 11 / 10 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00019686 | 0 / 0 |
| P42858 | Huntingtin | Unclassified protein | C00019686 | 1 / 1 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00019686 | 1 / 2 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00019686 | 0 / 0 |
| P04818 | Thymidylate synthase | Transferase | C00019686 | 0 / 0 |
| P00374 | Dihydrofolate reductase | Oxidoreductase | C00019686 | 1 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00019686 | 4 / 3 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00019686 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00019686 | 2 / 5 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 55312 | RFK, RIFK | riboflavin kinase (EC:2.7.1.26) |
C00019686
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #143100 | Huntington disease; hd |
P42858
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613839 | Megaloblastic anemia due to dihydrofolate reductase deficiency |
P00374
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01197 | Dihydrofolate reductase (DHFR) deficiency |
P00374
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|