KNApSAcK Metabolite C00021448
Metabolite
KNApSAcK Entry
| id | C00021448 |
|---|---|
| Name | Braxin C / Ptaquiloside |
| CAS RN | 87625-62-5 |
| Standard InChI | InChI=1S/C20H30O8/c1-9-6-20(28-17-15(25)14(24)13(23)11(8-21)27-17)7-10(2)19(4-5-19)18(3,26)16(20)12(9)22/h7,9,11,13-17,21,23-26H,4-6,8H2,1-3H3/t9-,11?,13-,14+,15?,16-,17+,18+,20-/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C20H30O8/c1-9-6-20(28-17-15(25)14(24)13(23)11(8-21)27-17)7-10(2)19(4-5-19)18(3,26)16(20)12(9)22/h7,9,11,13-17,21,23-26H,4-6,8H2,1-3H3 |
Cluster
| Phytochemical cluster | No. 84 |
|---|---|
| KCF-S cluster | No. 2532 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer |
KEGG
| By LinkDB | C19515 |
|---|
CTD
| By CAS RN | C043680 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| Euphyllophyta | 3 |
Family
| family name | count |
|---|---|
| Dennstaedtiaceae | 2 |
| Pteridaceae | 1 |
List (3)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Histiopteris incisa | 32090 | Dennstaedtiaceae | Euphyllophyta | Viridiplantae |
| Pteridium aquilinum | 32101 | Dennstaedtiaceae | Euphyllophyta | Viridiplantae |
| Pteris cretica | 49539 | Pteridaceae | Euphyllophyta | Viridiplantae |
Human Protein / Gene in interaction
CTD interaction (13)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C043680 | 308 |
ANXA5
ANX5 ENX2 PP4 RPRGL3 |
annexin A5 | ptaquiloside affects the expression of ANXA5 protein |
affects expression
|
protein |
22143989
|
| C043680 | 1111 |
CHEK1
CHK1 |
checkpoint kinase 1 (EC:2.7.11.1) | ptaquiloside results in increased phosphorylation of CHEK1 protein |
increases phosphorylation
|
protein |
22143989
|
| C043680 | 1649 |
DDIT3
CEBPZ CHOP CHOP-10 CHOP10 GADD153 |
DNA-damage-inducible transcript 3 | ptaquiloside results in decreased expression of DDIT3 mRNA |
decreases expression
|
mRNA |
22143989
|
| C043680 | 1647 |
GADD45A
DDIT1 GADD45 |
growth arrest and DNA-damage-inducible, alpha | ptaquiloside results in increased expression of GADD45A mRNA |
increases expression
|
mRNA |
22143989
|
| C043680 | 5608 |
MAP2K6
MAPKK6 MEK6 MKK6 PRKMK6 SAPKK-3 SAPKK3 |
mitogen-activated protein kinase kinase 6 (EC:2.7.12.2) | ptaquiloside results in decreased expression of MAP2K6 mRNA |
decreases expression
|
mRNA |
22143989
|
| C043680 | 4683 |
NBN
AT-V1 AT-V2 ATV NBS NBS1 P95 |
nibrin | ptaquiloside results in decreased expression of NBN mRNA |
decreases expression
|
mRNA |
22143989
|
| C043680 | 10111 |
RAD50
NBSLD RAD502 hRad50 |
RAD50 homolog (S. cerevisiae) | ptaquiloside results in decreased expression of RAD50 mRNA |
decreases expression
|
mRNA |
22143989
|
| C043680 | 5890 |
RAD51B
R51H2 RAD51L1 REC2 |
RAD51 paralog B | ptaquiloside results in decreased expression of RAD51B mRNA |
decreases expression
|
mRNA |
22143989
|
| C043680 | 27244 |
SESN1
PA26 SEST1 |
sestrin 1 | ptaquiloside results in increased expression of SESN1 mRNA |
increases expression
|
mRNA |
22143989
|
| C043680 | 7157 |
TP53
BCC7 LFS1 P53 TRP53 |
tumor protein p53 | ptaquiloside results in decreased expression of TP53 mRNA |
decreases expression
|
mRNA |
22143989
|
| C043680 | 7157 |
TP53
BCC7 LFS1 P53 TRP53 |
tumor protein p53 | ptaquiloside results in increased expression of TP53 mRNA |
increases expression
|
mRNA |
22143989
|
| C043680 | 7157 |
TP53
BCC7 LFS1 P53 TRP53 |
tumor protein p53 | ptaquiloside results in increased expression of TP53 protein |
increases expression
|
protein |
22143989
|
| C043680 | 7508 |
XPC
RAD4 XP3 XPCC |
xeroderma pigmentosum, complementation group C | ptaquiloside results in increased expression of XPC mRNA |
increases expression
|
mRNA |
22143989
|