phytochemical cluster No. 84 (12 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• KCF-S cluster (5)
• Metabolite list (12)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	10
Euphyllophyta	6
eudicotyledons	2
Spermatophyta	1

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Cumulative family count

class name	count
Dennstaedtiaceae	5
Sapindaceae	3
Anacardiaceae	3
Hippocastanaceae	2
Ranunculaceae	2
Ginkgoaceae	1
Brassicaceae	1
Enterobacteriaceae	1
Aceraceae	1
Pteridaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Others	5

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metabolites link (5)

br08003 Category	KEGG ID	KNApSAcK ID
Others	C07090	C00000301
Others	C08280	C00001360
Others	C08287	C00001372
Others	C10839	C00002681
Others	C19515	C00021448

KCF-S cluster (5)

KCF-S ID	# of metabolite
No. 2532	4
No. 3375	3
No. 5121	2
No. 5046	2
No. 8338	1

Metabolite list (12)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	figure
C00021448	Protoanemonin / Protoanemonene		C037354			No. 2532
C00021445	L-gamma-Glutamyl-L-cysteine	CHEMBL460831	C017341			No. 2532
C00021444	L-gamma-Glutamyl-L-hypoglycin					No. 2532
C00021443	alpha-(Methylenecyclopropyl)glycine		C059830			No. 2532
C00002635	Anacardic acid	CHEMBL33778		1 / 0 / 0		No. 3375
C00002651	Ginkgoic acid	CHEMBL277156 CHEMBL445177	C112485	11 / 9 / 9		No. 3375
C00002681	Urushiol III					No. 3375
C00001372	Hypoloside B		C062113			No. 5046
C00001381	Hypoloside C					No. 5046
C00007507	L-Hypoglycin	CHEMBL1615355	C041757			No. 5121
C00001360	Hypoloside A					No. 5121
C00000301	Braxin C / Ptaquiloside		C043680		11 / 1	No. 8338

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9UBE0	SUMO-activating enzyme subunit 1	Unclassified protein	C00002635 C00002651	0 / 0
P13726	Tissue factor	Membrane receptor	C00002651	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002651	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00002651	2 / 3
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00002651	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00002651	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002651	3 / 3
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002651	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002651	4 / 3
Q9UBT6	DNA polymerase kappa	Enzyme	C00002651	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002651	0 / 0

11 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
308	ANXA5, ANX5, ENX2, PP4, RPRGL3	annexin A5	C00021448
1111	CHEK1, CHK1	checkpoint kinase 1 (EC:2.7.11.1)	C00021448
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00021448
1647	GADD45A, DDIT1, GADD45	growth arrest and DNA-damage-inducible, alpha	C00021448
5608	MAP2K6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3	mitogen-activated protein kinase kinase 6 (EC:2.7.12.2)	C00021448
4683	NBN, AT-V1, AT-V2, ATV, NBS, NBS1, P95	nibrin	C00021448
10111	RAD50, NBSLD, RAD502, hRad50	RAD50 homolog (S. cerevisiae)	C00021448
5890	RAD51B, R51H2, RAD51L1, REC2	RAD51 paralog B	C00021448
27244	SESN1, PA26, SEST1	sestrin 1	C00021448
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00021448
7508	XPC, RAD4, XP3, XPCC	xeroderma pigmentosum, complementation group C	C00021448

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions