PCIDB

KNApSAcK Metabolite C00022389

Metabolite

KNApSAcK Entry

id C00022389
Name Coleonol C
CAS RN 67921-06-6
Standard InChI InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(28-12(2)23)17(26)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17+,19+,20-,21+,22-/m0/s1
Standard InChI (Main Layer) InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(28-12(2)23)17(26)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3

Cluster

Phytochemical cluster No. 41
KCF-S cluster No. 531

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL147617 CHEMBL1519619

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
asterids 1
rosids 1

Family

family name count
Lamiaceae 1
Euphorbiaceae 1

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Coleus forskohlii 41228 Lamiaceae asterids Viridiplantae
Excoecaria cochinchinensis 179682 Euphorbiaceae rosids Viridiplantae

Human Protein / Gene in interaction

5 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P37840 Alpha-synuclein Unclassified protein CHEMBL1519619 CHEMBL2354282 (1)
4 / 2
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL1519619 CHEMBL2114788 (1) CHEMBL2114931 (1)
0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL1519619 CHEMBL2114810 (1) CHEMBL2114817 (1)
7 / 3
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL1519619 CHEMBL1794401 (1)
0 / 0
Q9GZV3 High affinity choline transporter 1 Choline Na-symporter CHEMBL1519619 CHEMBL1794362 (1) CHEMBL1794546 (1)
1 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#127750 Dementia, lewy body; dlb P37840
#174800 Mccune-albright syndrome; mas P63092
#158580 Neuronopathy, distal hereditary motor, type viia; hmn7a Q9GZV3
#166350 Osseous heteroplasia, progressive; poh P63092
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092

KEGG DISEASE (5)

KEGG disease name UniProt
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)