PCIDB

KNApSAcK Metabolite C00002474

Index

Metabolite

Species

Human Protein
/ Gene in interactions

Related Diseases

Metabolite

KNApSAcK Entry

id	C00002474
Name	Fraxin
CAS RN	524-30-1
Standard InChI	InChI=1S/C16H18O10/c1-23-7-4-6-2-3-9(18)25-14(6)15(11(7)20)26-16-13(22)12(21)10(19)8(5-17)24-16/h2-4,8,10,12-13,16-17,19-22H,5H2,1H3/t8?,10-,12+,13?,16+/m1/s1
Standard InChI (Main Layer)	InChI=1S/C16H18O10/c1-23-7-4-6-2-3-9(18)25-14(6)15(11(7)20)26-16-13(22)12(21)10(19)8(5-17)24-16/h2-4,8,10,12-13,16-17,19-22H,5H2,1H3

Cluster

Phytochemical cluster	No. 25
KCF-S cluster	No. 491

Link

ChEMBL

By standard InChI
By standard InChI Main Layer	CHEMBL293864

KEGG

By LinkDB	C09266

CTD

By CAS RN	C080614

Species

Summary

Plant class

class name	count
asterids	5
rosids	3
Magnoliophyta	1

Family

family name	count
Caprifoliaceae	2
Oleaceae	2
Hippocastanaceae	1
Calycanthaceae	1
Campanulaceae	1
Malvaceae	1
Aceraceae	1

List (9)

* NCBI

KNApSAcK organism	*ID	*family	*plant class	*kingdom
Acer nikoense	171213	Aceraceae	rosids	Viridiplantae
Aesculus hippocastanum	43364	Hippocastanaceae	rosids	Viridiplantae
Campanula spp.	40568	Campanulaceae	asterids	Viridiplantae
Chimonanthus fragrans	13418	Calycanthaceae	Magnoliophyta	Viridiplantae
Diervilla spp.	19933	Caprifoliaceae	asterids	Viridiplantae
Fraxinus japonica Seringe Blume	38871	Oleaceae	asterids	Viridiplantae
Fraxinus spp.	38871	Oleaceae	asterids	Viridiplantae
Symphoricarpos spp.	13701	Caprifoliaceae	asterids	Viridiplantae
Tilia spp.	64580	Malvaceae	rosids	Viridiplantae

Human Protein / Gene in interaction

11 ChEMBL Protein in interactions

accession	description	class description	compound	assay ID (# of activities)	# of diseases (OMIM / KEGG)
Q99700	Ataxin-2	Unclassified protein	CHEMBL293864	CHEMBL2114784 (1)	1 / 1
P43166	Carbonic anhydrase 7	Lyase	CHEMBL293864	CHEMBL2341285 (1)	0 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	CHEMBL293864	CHEMBL2341282 (1)	0 / 0
P00918	Carbonic anhydrase 2	Lyase	CHEMBL293864	CHEMBL2341286 (1)	1 / 2
O43570	Carbonic anhydrase 12	Lyase	CHEMBL293864	CHEMBL2341283 (1)	1 / 2
Q92830	Histone acetyltransferase KAT2A	Enzyme	CHEMBL293864	CHEMBL1738606 (1)	0 / 0
O75496	Geminin	Unclassified protein	CHEMBL293864	CHEMBL2114843 (1) CHEMBL2114780 (1)	0 / 0
P00915	Carbonic anhydrase 1	Lyase	CHEMBL293864	CHEMBL2341287 (1)	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	CHEMBL293864	CHEMBL2341284 (1)	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	CHEMBL293864	CHEMBL1794483 (1)	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	CHEMBL293864	CHEMBL2114738 (1)	0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM	preferred title	UniProt
#143860	Hyperchlorhidrosis, isolated	O43570
#259730	Osteopetrosis, autosomal recessive 3; optb3	P00918
#183090	Spinocerebellar ataxia 2; sca2	Q99700

KEGG DISEASE (5)

KEGG	disease name	UniProt
H01302	Hyperchlorhidrosis isolated (HCHLH)	O43570 (related)
H00021	Renal cell carcinoma	O43570 (marker) Q16790 (marker)
H00241	Combined proximal and distal renal tubular acidosis (RTA type 3)	P00918 (related)
H00436	Osteopetrosis	P00918 (related)
H00063	Spinocerebellar ataxia (SCA)	Q99700 (related)