PCIDB

KNApSAcK Metabolite C00002564

Metabolite

KNApSAcK Entry

id C00002564
Name Prunetin / Prunusetin / Padmakastein / 5,4'-Dihydroxy-7-methoxyisoflavone
CAS RN 552-59-0
Standard InChI InChI=1S/C16H12O5/c1-20-11-6-13(18)15-14(7-11)21-8-12(16(15)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3
Standard InChI (Main Layer) InChI=1S/C16H12O5/c1-20-11-6-13(18)15-14(7-11)21-8-12(16(15)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 3

Link

ChEMBL

By standard InChI CHEMBL491174
By standard InChI Main Layer CHEMBL491174

KEGG

By LinkDB C10521

CTD

By CAS RN C083295

Human Protein / Gene in interaction

6 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P05091 Aldehyde dehydrogenase, mitochondrial Oxidoreductase CHEMBL491174 CHEMBL989246 (1)
1 / 1
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily CHEMBL491174 CHEMBL941404 (1)
1 / 11
P11388 DNA topoisomerase 2-alpha Isomerase CHEMBL491174 CHEMBL1014685 (1) CHEMBL1014691 (1)
CHEMBL1014692 (1) CHEMBL1014693 (1)
0 / 0
P15121 Aldose reductase Enzyme CHEMBL491174 CHEMBL1942675 (1)
0 / 0
P04150 Glucocorticoid receptor NR3C1 CHEMBL491174 CHEMBL1052488 (1) CHEMBL1052489 (1)
0 / 1
P10275 Androgen receptor NR3C4 CHEMBL491174 CHEMBL1052486 (1) CHEMBL1052498 (1)
3 / 4

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#610251 Alcohol sensitivity, acute P05091
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#211980 Lung cancer P00533
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275

KEGG DISEASE (14)

KEGG disease name UniProt
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
H00018 Gastric cancer P00533 (related)
H00022 Bladder cancer P00533 (related)
H00028 Choriocarcinoma P00533 (related)
H00030 Cervical cancer P00533 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H01071 Acute alcohol sensitivity P05091 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)