Species

KNApSAcK Entry

Organism name Streptomyces sp. M491
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces sp. M491
Linked NCBI taxonomy ID 345410
Linked level species

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002564 External link 512 Prunetin
/ Prunusetin
/ Padmakastein
/ 5,4'-Dihydroxy-7-methoxyisoflavone
CHEMBL491174
C083295
6 / 5 / 14 No. 3 No. 15
C00038117 External link 512 10alpha,11-Dihydroxyamorph-4-ene
CHEMBL221435
No. 3823
C00000112 External link 512 Indole-3-carboxaldehyde
/ 1H-Indole-3-carboxaldehyde
CHEMBL147741
C012381
2 / 1 / 1 No. 4314

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P12268 Inosine-5'-monophosphate dehydrogenase 2 Oxidoreductase C00000112 0 / 0
P05091 Aldehyde dehydrogenase, mitochondrial Oxidoreductase C00002564 1 / 1
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00002564 1 / 8
P11388 DNA topoisomerase 2-alpha Isomerase C00002564 0 / 0
P15121 Aldose reductase Enzyme C00002564 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00002564 0 / 1
P00374 Dihydrofolate reductase Oxidoreductase C00000112 1 / 1
P10275 Androgen receptor NR3C4 C00002564 3 / 4

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#610251 Alcohol sensitivity, acute P05091
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#211980 Lung cancer P00533
#613839 Megaloblastic anemia due to dihydrofolate reductase deficiency P00374
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275

KEGG DISEASE (15)

KEGG name UniProt
H01197 Dihydrofolate reductase (DHFR) deficiency P00374 (related)
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
H00018 Gastric cancer P00533 (related)
H00022 Bladder cancer P00533 (related)
H00028 Choriocarcinoma P00533 (related)
H00030 Cervical cancer P00533 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H01071 Acute alcohol sensitivity P05091 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)