PCIDB

KNApSAcK Metabolite C00026316

Metabolite

KNApSAcK Entry

id C00026316
Name 4-Hydroxycinnamate
CAS RN 878-01-3
Standard InChI InChI=1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)/p-1/b6-3+
Standard InChI (Main Layer) InChI=1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)

Cluster

Phytochemical cluster No. 6
KCF-S cluster No. 904

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL66879 CHEMBL2336752

KEGG

By LinkDB C00811

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 2

Family

family name count
Fabaceae 2

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Lupinus cosentinii Guss. 53222 Fabaceae rosids Viridiplantae
Lupinus luteus L. 3873 Fabaceae rosids Viridiplantae

Human Protein / Gene in interaction

23 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P17516 Aldo-keto reductase family 1 member C4 Enzyme CHEMBL66879 CHEMBL2038591 (1)
1 / 0
O60218 Aldo-keto reductase family 1 member B10 Enzyme CHEMBL66879 CHEMBL1942331 (1)
0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase CHEMBL66879 CHEMBL1014033 (1)
0 / 3
Q13093 Platelet-activating factor acetylhydrolase Enzyme CHEMBL66879 CHEMBL1032505 (1)
3 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase CHEMBL66879 CHEMBL1074270 (1)
0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase CHEMBL66879 CHEMBL1074269 (1)
0 / 0
P43166 Carbonic anhydrase 7 Lyase CHEMBL66879 CHEMBL1074272 (1)
0 / 0
P00918 Carbonic anhydrase 2 Lyase CHEMBL66879 CHEMBL1074266 (1)
1 / 2
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily CHEMBL66879 CHEMBL674643 (1) CHEMBL675636 (1)
1 / 11
P23280 Carbonic anhydrase 6 Lyase CHEMBL66879 CHEMBL1074271 (1)
0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase CHEMBL66879 CHEMBL1074276 (1)
0 / 0
O43570 Carbonic anhydrase 12 Lyase CHEMBL66879 CHEMBL1074274 (1)
1 / 2
P42330 Aldo-keto reductase family 1 member C3 Enzyme CHEMBL66879 CHEMBL2038590 (1)
0 / 0
Q8TDS4 Hydroxycarboxylic acid receptor 2 Hydroxycarboxylic acid receptor CHEMBL66879 CHEMBL1772553 (1)
0 / 0
P15121 Aldose reductase Enzyme CHEMBL66879 CHEMBL984565 (1) CHEMBL1942330 (1)
0 / 0
P00915 Carbonic anhydrase 1 Lyase CHEMBL66879 CHEMBL1074265 (1)
0 / 0
P14679 Tyrosinase Oxidoreductase CHEMBL66879 CHEMBL870666 (1)
4 / 2
Q16790 Carbonic anhydrase 9 Lyase CHEMBL66879 CHEMBL1074273 (1)
0 / 1
Q04828 Aldo-keto reductase family 1 member C1 Enzyme CHEMBL66879 CHEMBL2038588 (1)
0 / 0
P03372 Estrogen receptor NR3A1 CHEMBL66879 CHEMBL1941568 (1) CHEMBL1941569 (1)
1 / 1
P52895 Aldo-keto reductase family 1 member C2 Enzyme CHEMBL66879 CHEMBL2038589 (1)
1 / 0
P07451 Carbonic anhydrase 3 Lyase CHEMBL66879 CHEMBL1074267 (1)
0 / 0
P22748 Carbonic anhydrase 4 Lyase CHEMBL66879 CHEMBL1074268 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#614279 46,xy sex reversal 8; srxy8 P17516
P52895
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#600807 Asthma, susceptibility to Q13093
#615363 Estrogen resistance; estrr P03372
#143860 Hyperchlorhidrosis, isolated O43570
#147050 Ige responsiveness, atopic; iger Q13093
#211980 Lung cancer P00533
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093
#600852 Retinitis pigmentosa 17; rp17 P22748
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679

KEGG DISEASE (18)

KEGG disease name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
H00022 Bladder cancer P00533 (related)
H00028 Choriocarcinoma P00533 (related)
H00030 Cervical cancer P00533 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00026 Endometrial Cancer P03372 (marker)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)