PCIDB

Lupinus luteus L.

Family in NCBI taxonomy	Fabaceae
ID	3803

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class	rosids
ID	71275

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00026316	4-Hydroxycinnamate	CHEMBL66879 CHEMBL2336752		23 / 13 / 18		No. 904	No. 6
C00026258	Lupinyl trans-p-coumarate / (-)-(trans-4'-Hydroxycinnamoyl)lupinine					No. 1926

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P17516	Aldo-keto reductase family 1 member C4	Enzyme	C00026316	1 / 0
O60218	Aldo-keto reductase family 1 member B10	Enzyme	C00026316	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00026316	0 / 3
Q13093	Platelet-activating factor acetylhydrolase	Enzyme	C00026316	3 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00026316	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00026316	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00026316	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00026316	1 / 2
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00026316	1 / 8
P23280	Carbonic anhydrase 6	Lyase	C00026316	0 / 0
Q9ULX7	Carbonic anhydrase 14	Lyase	C00026316	0 / 0
O43570	Carbonic anhydrase 12	Lyase	C00026316	1 / 2
P42330	Aldo-keto reductase family 1 member C3	Enzyme	C00026316	0 / 0
Q8TDS4	Hydroxycarboxylic acid receptor 2	Hydroxycarboxylic acid receptor	C00026316	0 / 0
P15121	Aldose reductase	Enzyme	C00026316	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00026316	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00026316	4 / 2
Q16790	Carbonic anhydrase 9	Lyase	C00026316	0 / 1
Q04828	Aldo-keto reductase family 1 member C1	Enzyme	C00026316	0 / 0
P03372	Estrogen receptor	NR3A1	C00026316	1 / 1
P52895	Aldo-keto reductase family 1 member C2	Enzyme	C00026316	1 / 0
P07451	Carbonic anhydrase 3	Lyase	C00026316	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00026316	1 / 1

OMIM	preferred title	UniProt
#614279	46,xy sex reversal 8; srxy8	P17516 P52895
#103470	Albinism, ocular, with sensorineural deafness	P14679
#203100	Albinism, oculocutaneous, type ia; oca1a	P14679
#606952	Albinism, oculocutaneous, type ib; oca1b	P14679
#600807	Asthma, susceptibility to	Q13093
#615363	Estrogen resistance; estrr	P03372
#143860	Hyperchlorhidrosis, isolated	O43570
#147050	Ige responsiveness, atopic; iger	Q13093
#211980	Lung cancer	P00533
#259730	Osteopetrosis, autosomal recessive 3; optb3	P00918
#614278	Platelet-activating factor acetylhydrolase deficiency; pafad	Q13093
#600852	Retinitis pigmentosa 17; rp17	P22748
#601800	Skin/hair/eye pigmentation, variation in, 3; shep3	P14679

KEGG	name	UniProt
H01302	Hyperchlorhidrosis isolated (HCHLH)	O43570 (related)
H00021	Renal cell carcinoma	O43570 (marker) Q16790 (marker)
H00016	Oral cancer	P00533 (related) P00533 (marker)
H00017	Esophageal cancer	P00533 (related) P35354 (related)
H00018	Gastric cancer	P00533 (related)
H00022	Bladder cancer	P00533 (related)
H00028	Choriocarcinoma	P00533 (related)
H00030	Cervical cancer	P00533 (related)
H00042	Glioma	P00533 (related) P00533 (marker)
H00055	Laryngeal cancer	P00533 (related) P00533 (marker)
H00241	Combined proximal and distal renal tubular acidosis (RTA type 3)	P00918 (related)
H00436	Osteopetrosis	P00918 (related)
H00026	Endometrial Cancer	P03372 (marker)
H00168	Oculocutaneous albinism (OCA)	P14679 (related)
H00038	Malignant melanoma	P14679 (marker)
H00527	Retinitis pigmentosa (RP)	P22748 (related)
H00025	Penile cancer	P35354 (related)
H00046	Cholangiocarcinoma	P35354 (related)