KNApSAcK Metabolite C00027729
Metabolite
KNApSAcK Entry
| id | C00027729 |
|---|---|
| Name | 2-O-Demethylcolchicine / (-)-2-Demethylcolchicine |
| CAS RN | 7336-36-9 |
| Standard InChI | InChI=1S/C21H23NO6/c1-11(23)22-15-7-5-12-9-18(27-3)20(25)21(28-4)19(12)13-6-8-17(26-2)16(24)10-14(13)15/h6,8-10,15,25H,5,7H2,1-4H3,(H,22,23)/t15-/m0/s1 |
| Standard InChI (Main Layer) | InChI=1S/C21H23NO6/c1-11(23)22-15-7-5-12-9-18(27-3)20(25)21(28-4)19(12)13-6-8-17(26-2)16(24)10-14(13)15/h6,8-10,15,25H,5,7H2,1-4H3,(H,22,23) |
Cluster
| Phytochemical cluster | No. 4 |
|---|---|
| KCF-S cluster | No. 598 |
Link
ChEMBL
| By standard InChI | CHEMBL1080 |
|---|---|
| By standard InChI Main Layer | CHEMBL1080 CHEMBL325328 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| Liliopsida | 3 |
Family
| family name | count |
|---|---|
| Colchicaceae | 3 |
List (3)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Colchicum megaphylla | 13444 | Colchicaceae | Liliopsida | Viridiplantae |
| Merendera raddeana | 217491 | Colchicaceae | Liliopsida | Viridiplantae |
| Merendera robusta | 481258 | Colchicaceae | Liliopsida | Viridiplantae |
Human Protein / Gene in interaction
15 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q9H4B7 | Tubulin beta-1 chain | Structural | CHEMBL1080 |
CHEMBL820637
(1)
CHEMBL833500
(1)
|
1 / 0 |
| Q13748 | Tubulin alpha-3C/D chain | Structural | CHEMBL1080 |
CHEMBL820637
(1)
|
0 / 0 |
| P68366 | Tubulin alpha-4A chain | Structural | CHEMBL1080 |
CHEMBL820637
(1)
|
0 / 0 |
| P04350 | Tubulin beta-4A chain | Structural | CHEMBL1080 |
CHEMBL820637
(1)
|
2 / 0 |
| Q3ZCM7 | Tubulin beta-8 chain | Structural | CHEMBL1080 |
CHEMBL820637
(1)
|
0 / 0 |
| P07437 | Tubulin beta chain | Structural | CHEMBL1080 |
CHEMBL820637
(1)
|
0 / 0 |
| Q71U36 | Tubulin alpha-1A chain | Structural | CHEMBL1080 |
CHEMBL820637
(1)
|
1 / 1 |
| P68371 | Tubulin beta-4B chain | Structural | CHEMBL1080 |
CHEMBL820637
(1)
|
0 / 0 |
| Q13509 | Tubulin beta-3 chain | Structural | CHEMBL1080 |
CHEMBL820637
(1)
|
2 / 1 |
| P68363 | Tubulin alpha-1B chain | Unclassified protein | CHEMBL1080 |
CHEMBL820637
(1)
|
0 / 0 |
| Q13885 | Tubulin beta-2A chain | Structural | CHEMBL1080 |
CHEMBL820637
(1)
|
0 / 0 |
| Q6PEY2 | Tubulin alpha-3E chain | Unclassified protein | CHEMBL1080 |
CHEMBL820637
(1)
|
0 / 0 |
| Q9BQE3 | Tubulin alpha-1C chain | Unclassified protein | CHEMBL1080 |
CHEMBL820637
(1)
|
0 / 0 |
| Q9BUF5 | Tubulin beta-6 chain | Structural | CHEMBL1080 |
CHEMBL820637
(1)
|
0 / 0 |
| Q9BVA1 | Tubulin beta-2B chain | Structural | CHEMBL1080 |
CHEMBL820637
(1)
|
1 / 0 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (7)
| OMIM | preferred title | UniProt |
|---|---|---|
| #614039 | Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 |
Q13509
|
| #128101 | Dystonia 4, torsion, autosomal dominant; dyt4 |
P04350
|
| #600638 | Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a |
Q13509
|
| #612438 | Leukodystrophy, hypomyelinating, 6; hld6 |
P04350
|
| #611603 | Lissencephaly 3; lis3 |
Q71U36
|
| #613112 | Macrothrombocytopenia, autosomal dominant, tubb1-related |
Q9H4B7
|
| #610031 | Polymicrogyria, symmetric or asymmetric; pmgysa |
Q9BVA1
|