PCIDB

KNApSAcK Metabolite C00029528

Metabolite

KNApSAcK Entry

id C00029528
Name 4-Ethylphenol
CAS RN 123-07-9
Standard InChI InChI=1S/C8H10O/c1-2-7-3-5-8(9)6-4-7/h3-6,9H,2H2,1H3
Standard InChI (Main Layer) InChI=1S/C8H10O/c1-2-7-3-5-8(9)6-4-7/h3-6,9H,2H2,1H3

Cluster

Phytochemical cluster No. 6
KCF-S cluster No. 936

Link

ChEMBL

By standard InChI CHEMBL108475
By standard InChI Main Layer CHEMBL108475

KEGG

By LinkDB C13637

CTD

By CAS RN C042291

Species

Summary

Plant class

class name count
Spermatophyta 1

Family

family name count
Podocarpaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Podocarpus fasciculus 120615 Podocarpaceae Spermatophyta Viridiplantae

Human Protein / Gene in interaction

3 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P50225 Sulfotransferase 1A1 Enzyme CHEMBL108475 CHEMBL1743314 (1)
0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme CHEMBL108475 CHEMBL1908086 (2)
0 / 0
P19224 UDP-glucuronosyltransferase 1-6 Enzyme CHEMBL108475 CHEMBL1908083 (4)
0 / 0

CTD interaction (3)

compound gene gene name gene description interaction interaction type form reference
pmid
C042291 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 4-ethylphenol binds to ESR1 protein affects binding
protein 12598185
19913605
C042291 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) 4-ethylphenol binds to ESR2 protein affects binding
protein 12224631
19913605
C042291 9970 NR1I3
CAR
CAR1
MB67
nuclear receptor subfamily 1, group I, member 3 [4-ethylphenol co-treated with PK 11195] results in decreased activity of NR1I3 protein alternative form affects cotreatment
/ decreases activity
protein 20869355