PCIDB

KNApSAcK Metabolite C00002969

Metabolite

KNApSAcK Entry

id C00002969
Name Norlichexanthone
CAS RN 20716-98-7
Standard InChI InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3
Standard InChI (Main Layer) InChI=1S/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 71

Link

ChEMBL

By standard InChI CHEMBL466154
By standard InChI Main Layer CHEMBL466154

KEGG

By LinkDB C10087

CTD

By CAS RN

Species

Summary

Plant class

class name count

Family

family name count
Lecanoraceae 1

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Lecanora iseana
Lecanora reuteri 108948 Lecanoraceae Fungi

Human Protein / Gene in interaction

17 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q02750 Dual specificity mitogen-activated protein kinase kinase 1 Ste7 CHEMBL466154 CHEMBL1816869 (1)
1 / 1
P08069 Insulin-like growth factor 1 receptor TK tyrosine-protein kinase INSR subfamily CHEMBL466154 CHEMBL1816868 (1)
1 / 3
Q16512 Serine/threonine-protein kinase N1 Pkn CHEMBL466154 CHEMBL1816875 (1)
0 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim CHEMBL466154 CHEMBL1816873 (1)
0 / 0
Q05397 Focal adhesion kinase 1 Fak CHEMBL466154 CHEMBL1816867 (1)
0 / 0
P51955 Serine/threonine-protein kinase Nek2 Nek CHEMBL466154 CHEMBL1816871 (1)
0 / 0
Q9UM73 ALK tyrosine kinase receptor TKL serine/threonine protein kinase STKR type 1 subfamily CHEMBL466154 CHEMBL1816863 (1)
1 / 1
O60285 NUAK family SNF1-like kinase 1 CAMK serine/threonine protein kinase NUAK subfamily CHEMBL466154 CHEMBL1816864 (1)
0 / 0
P12931 Proto-oncogene tyrosine-protein kinase Src Src CHEMBL466154 CHEMBL1816876 (1)
0 / 0
Q96GD4 Aurora kinase B Aur CHEMBL466154 CHEMBL1816865 (1)
0 / 0
P35968 Vascular endothelial growth factor receptor 2 Vegfr CHEMBL466154 CHEMBL1816877 (1)
1 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily CHEMBL466154 CHEMBL1816870 (1)
2 / 3
P53350 Serine/threonine-protein kinase PLK1 PLK serine/threonine protein kinase subfamily CHEMBL466154 CHEMBL1816874 (1)
0 / 0
P31749 RAC-alpha serine/threonine-protein kinase Akt CHEMBL466154 CHEMBL1816862 (1)
4 / 1
Q9HC98 Serine/threonine-protein kinase Nek6 Nek CHEMBL466154 CHEMBL1816872 (1)
0 / 0
P06239 Tyrosine-protein kinase Lck Src CHEMBL466154 CHEMBL985773 (1)
0 / 1
P30530 Tyrosine-protein kinase receptor UFO TK tyrosine-protein kinase AXL subfamily CHEMBL466154 CHEMBL1816866 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#114480 Breast cancer P31749
#615279 Cardiofaciocutaneous syndrome 3; cfc3 Q02750
#114500 Colorectal cancer; crc P31749
#615109 Cowden syndrome 6; cws6 P31749
#602089 Hemangioma, capillary infantile P35968
#114550 Hepatocellular carcinoma P08581
#270450 Insulin-like growth factor i, resistance to P08069
#613014 Neuroblastoma, susceptibility to, 3; nblst3 Q9UM73
#176920 Proteus syndrome P31749
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581

KEGG DISEASE (10)

KEGG disease name UniProt
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00015 Malignant pleural mesothelioma P08069 (related)
H00050 Synovial sarcoma P08069 (related)
H01274 Growth delay due to insulin-like growth factor I resistance P08069 (related)
H00018 Gastric cancer P08581 (related)
H00021 Renal cell carcinoma P08581 (related)
H00046 Cholangiocarcinoma P08581 (related)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H00523 Noonan syndrome and related disorders Q02750 (related)
H00014 Non-small cell lung cancer Q9UM73 (related)