Lecanora iseana
Metabolite list (7)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00002969
|
Norlichexanthone
|
CHEMBL466154
|
17 / 10 / 10 | No. 71 | No. 15 |
|
||
|
C00035225
|
4,5-Dichloronorlichexanthone
|
No. 1440 |
|
|||||
|
C00035412
|
Thiophanic acid
|
No. 1440 |
|
|||||
|
C00035214
|
2,4-Dichloronorlichexanthone
|
No. 1440 |
|
|||||
|
C00035246
|
Arthothelin
|
No. 1440 |
|
|||||
|
C00035227
|
4-Chloronorlichexanthone
|
No. 1440 |
|
|||||
|
C00035219
|
3,7-Dihydroxy-1,9-dimethyldibenzofuran
|
No. 2735 |
|
Human Protein / Gene in interactions
17 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | Ste7 | C00002969 | 1 / 1 |
| P08069 | Insulin-like growth factor 1 receptor | TK tyrosine-protein kinase INSR subfamily | C00002969 | 1 / 3 |
| Q16512 | Serine/threonine-protein kinase N1 | Pkn | C00002969 | 0 / 0 |
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00002969 | 0 / 0 |
| Q05397 | Focal adhesion kinase 1 | Fak | C00002969 | 0 / 0 |
| P51955 | Serine/threonine-protein kinase Nek2 | Nek | C00002969 | 0 / 0 |
| Q9UM73 | ALK tyrosine kinase receptor | TKL serine/threonine protein kinase STKR type 1 subfamily | C00002969 | 1 / 1 |
| O60285 | NUAK family SNF1-like kinase 1 | CAMK serine/threonine protein kinase NUAK subfamily | C00002969 | 0 / 0 |
| P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00002969 | 0 / 0 |
| Q96GD4 | Aurora kinase B | Aur | C00002969 | 0 / 0 |
| P35968 | Vascular endothelial growth factor receptor 2 | Vegfr | C00002969 | 1 / 0 |
| P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00002969 | 2 / 3 |
| P53350 | Serine/threonine-protein kinase PLK1 | PLK serine/threonine protein kinase subfamily | C00002969 | 0 / 0 |
| P31749 | RAC-alpha serine/threonine-protein kinase | Akt | C00002969 | 4 / 1 |
| Q9HC98 | Serine/threonine-protein kinase Nek6 | Nek | C00002969 | 0 / 0 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00002969 | 0 / 1 |
| P30530 | Tyrosine-protein kinase receptor UFO | TK tyrosine-protein kinase AXL subfamily | C00002969 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (10)
| OMIM | preferred title | UniProt |
|---|---|---|
| #114480 | Breast cancer |
P31749
|
| #615279 | Cardiofaciocutaneous syndrome 3; cfc3 |
Q02750
|
| #114500 | Colorectal cancer; crc |
P31749
|
| #615109 | Cowden syndrome 6; cws6 |
P31749
|
| #602089 | Hemangioma, capillary infantile |
P35968
|
| #114550 | Hepatocellular carcinoma |
P08581
|
| #270450 | Insulin-like growth factor i, resistance to |
P08069
|
| #613014 | Neuroblastoma, susceptibility to, 3; nblst3 |
Q9UM73
|
| #176920 | Proteus syndrome |
P31749
|
| #605074 | Renal cell carcinoma, papillary, 1; rccp1 |
P08581
|
KEGG DISEASE (10)
| KEGG | name | UniProt |
|---|---|---|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00015 | Malignant pleural mesothelioma |
P08069
(related)
|
| H00050 | Synovial sarcoma |
P08069
(related)
|
| H01274 | Growth delay due to insulin-like growth factor I resistance |
P08069
(related)
|
| H00018 | Gastric cancer |
P08581
(related)
|
| H00021 | Renal cell carcinoma |
P08581
(related)
|
| H00046 | Cholangiocarcinoma |
P08581
(related)
|
| H00539 | PTEN hamartoma tumor syndrome (PHTS) |
P31749
(related)
|
| H00523 | Noonan syndrome and related disorders |
Q02750
(related)
|
| H00014 | Non-small cell lung cancer |
Q9UM73
(related)
|