KNApSAcK Metabolite C00029799
Metabolite
KNApSAcK Entry
| id | C00029799 |
|---|---|
| Name | Bastadin 7 |
| CAS RN | 79067-73-5 |
| Standard InChI | InChI=1S/C34H26Br4N4O8/c35-21-9-17-1-3-27(21)49-29-15-19(11-23(37)31(29)43)6-8-40-33(45)25(41-47)13-18-2-4-28(22(36)10-18)50-30-16-20(12-24(38)32(30)44)14-26(42-48)34(46)39-7-5-17/h1-5,7,9-12,15-16,43-44,47-48H,6,8,13-14H2,(H,39,46)(H,40,45)/b7-5-,41-25-,42-26+ |
| Standard InChI (Main Layer) | InChI=1S/C34H26Br4N4O8/c35-21-9-17-1-3-27(21)49-29-15-19(11-23(37)31(29)43)6-8-40-33(45)25(41-47)13-18-2-4-28(22(36)10-18)50-30-16-20(12-24(38)32(30)44)14-26(42-48)34(46)39-7-5-17/h1-5,7,9-12,15-16,43-44,47-48H,6,8,13-14H2,(H,39,46)(H,40,45) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 651 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer | CHEMBL360190 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Ianthellidae | 2 |
List (2)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Ianthella basta | 375146 | Ianthellidae | Metazoa | |
| Ianthella quadrangulata | 1162752 | Ianthellidae | Metazoa |
Human Protein / Gene in interaction
23 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P08069 | Insulin-like growth factor 1 receptor | TK tyrosine-protein kinase INSR subfamily | CHEMBL360190 |
CHEMBL2345560
(1)
|
1 / 3 |
| O14965 | Aurora kinase A | Aur | CHEMBL360190 |
CHEMBL2344168
(1)
|
0 / 0 |
| O00444 | Serine/threonine-protein kinase PLK4 | PLK serine/threonine protein kinase subfamily | CHEMBL360190 |
CHEMBL2345556
(1)
|
0 / 0 |
| P11802 | Cyclin-dependent kinase 4 | CMGC serine/threonine protein kinase family | CHEMBL360190 |
CHEMBL2344163
(1)
|
1 / 3 |
| P24385 | G1/S-specific cyclin-D1 | Other cytosolic protein | CHEMBL360190 |
CHEMBL2344163
(1)
|
1 / 10 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | CHEMBL360190 |
CHEMBL2344161
(1)
|
1 / 11 |
| P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | CHEMBL360190 |
CHEMBL2344158
(1)
|
1 / 1 |
| P54760 | Ephrin type-B receptor 4 | Eph | CHEMBL360190 |
CHEMBL2344159
(1)
|
0 / 0 |
| P21817 | Ryanodine receptor 1 | CA | CHEMBL360190 |
CHEMBL1006192
(1)
|
4 / 2 |
| Q05397 | Focal adhesion kinase 1 | Fak | CHEMBL360190 |
CHEMBL2344156
(1)
|
0 / 0 |
| Q02763 | Angiopoietin-1 receptor | Tie | CHEMBL360190 |
CHEMBL2345554
(1)
|
1 / 1 |
| O60285 | NUAK family SNF1-like kinase 1 | CAMK serine/threonine protein kinase NUAK subfamily | CHEMBL360190 |
CHEMBL2344169
(1)
|
0 / 0 |
| P06213 | Insulin receptor | TK tyrosine-protein kinase INSR subfamily | CHEMBL360190 |
CHEMBL2344157
(1)
|
5 / 4 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | CHEMBL360190 |
CHEMBL2344160
(1)
|
5 / 10 |
| P09619 | Platelet-derived growth factor receptor beta | Pdgfr | CHEMBL360190 |
CHEMBL2345558
(1)
|
5 / 1 |
| P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | CHEMBL360190 |
CHEMBL2345555
(1)
|
0 / 0 |
| Q96GD4 | Aurora kinase B | Aur | CHEMBL360190 |
CHEMBL2344167
(1)
|
0 / 0 |
| P35968 | Vascular endothelial growth factor receptor 2 | Vegfr | CHEMBL360190 |
CHEMBL2345552
(1)
|
1 / 0 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | CHEMBL360190 |
CHEMBL833559
(1)
|
2 / 0 |
| P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | CHEMBL360190 |
CHEMBL2345559
(1)
|
2 / 3 |
| P35916 | Vascular endothelial growth factor receptor 3 | Vegfr | CHEMBL360190 |
CHEMBL2345553
(1)
|
2 / 1 |
| P41279 | Mitogen-activated protein kinase kinase kinase 8 | Ste11 | CHEMBL360190 |
CHEMBL2344162
(1)
|
0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | CHEMBL360190 |
CHEMBL831078
(1)
|
0 / 0 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (29)
| OMIM | preferred title | UniProt |
|---|---|---|
| #615007 | Basal ganglia calcification, idiopathic, 4; ibgc4 |
P09619
|
| #117000 | Central core disease of muscle |
P21817
|
| #114500 | Colorectal cancer; crc |
P18054
|
| #610549 | Diabetes mellitus, insulin-resistant, with acanthosis nigricans |
P06213
|
| #125853 | Diabetes mellitus, noninsulin-dependent; niddm |
P06213
|
| #246200 | Donohue syndrome |
P06213
|
| #133239 | Esophageal cancer |
P18054
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #137800 | Glioma susceptibility 1; glm1 |
P04626
|
| #602089 | Hemangioma, capillary infantile |
P35916
P35968 |
| #114550 | Hepatocellular carcinoma |
P08581
|
| #609968 | Hyperinsulinemic hypoglycemia, familial, 5; hhf5 |
P06213
|
| #270450 | Insulin-like growth factor i, resistance to |
P08069
|
| #607785 | Juvenile myelomonocytic leukemia; jmml |
P09619
|
| #601626 | Leukemia, acute myeloid; aml |
P09619
P36888 |
| #211980 | Lung cancer |
P00533
P04626 |
| #153100 | Lymphedema, hereditary, ia |
P35916
|
| #145600 | Malignant hyperthermia, susceptibility to, 1; mhs1 |
P21817
|
| #609048 | Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 |
P11802
|
| #255320 | Minicore myopathy with external ophthalmoplegia |
P21817
|
| #254500 | Myeloma, multiple |
P24385
|
| #131440 | Myeloproliferative disorder, chronic, with eosinophilia |
P09619
|
| #228550 | Myofibromatosis, infantile, 1; imf1 |
P09619
|
| #255310 | Myopathy, congenital, with fiber-type disproportion; cftd |
P21817
|
| #167000 | Ovarian cancer |
P04626
|
| #262190 | Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities |
P06213
|
| #605074 | Renal cell carcinoma, papillary, 1; rccp1 |
P08581
|
| #600195 | Venous malformations, multiple cutaneous and mucosal; vmcm |
Q02763
|
KEGG DISEASE (31)
| KEGG | disease name | UniProt |
|---|---|---|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P24385 (related) P24385 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P24385 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P08581 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P04626 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) P11802 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P09619 (related) P11802 (related) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P24385 (related) P24385 (marker) |
| H00019 | Pancreatic cancer |
P04626
(related)
|
| H00026 | Endometrial Cancer |
P04626
(related)
|
| H00027 | Ovarian cancer |
P04626
(related)
|
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P24385 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P08581 (related) |
| H00719 | Leprechaunism |
P06213
(related)
|
| H00942 | Rabson-Mendenhall syndrome |
P06213
(related)
|
| H01228 | Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) |
P06213
(related)
|
| H01267 | Familial hyperinsulinemic hypoglycemia (HHF) |
P06213
(related)
|
| H00015 | Malignant pleural mesothelioma |
P08069
(related)
|
| H00050 | Synovial sarcoma |
P08069
(related)
|
| H01274 | Growth delay due to insulin-like growth factor I resistance |
P08069
(related)
|
| H00021 | Renal cell carcinoma |
P08581
(related)
|
| H00038 | Malignant melanoma |
P11802
(related)
|
| H00699 | Central core disease |
P21817
(related)
|
| H01310 | Multi-minicore disease (MmD) |
P21817
(related)
|
| H00006 | Hairy-cell leukemia |
P24385
(related)
|
| H00010 | Multiple myeloma |
P24385
(related)
|
| H00559 | von Hippel-Lindau syndrome |
P24385
(related)
|
| H00047 | Gallbladder cancer |
P24385
(marker)
|
| H00535 | Lymphedemas |
P35916
(related)
|
| H00003 | Acute myeloid leukemia (AML) |
P36888
(related)
|
| H00531 | Venous malformations |
Q02763
(related)
|