Species

KNApSAcK Entry

Organism name Ianthella basta
Genus
Family
Kingdom

NCBI taxonomy

Entry

Linked NCBI taxonomy name Ianthella basta
Linked NCBI taxonomy ID 375146
Linked level species

Family

Family in NCBI taxonomy Ianthellidae
ID 252952

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Metazoa
ID 33208

Plant class

Plant class
ID

Metabolite list (13)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00023068 External link 512 Bastaxanthol C
/ (1'R,3R,5'R)-7,8-Didehydro-3,16',19-trihydroxy-beta,kappa-carotene-3',6'-dione
No. 262 No. 59
C00023071 External link 512 Bastaxanthol B
/ (1'R,3R,5'R)-7,8-Didehydro-3,19-dihydroxy-3',6'-dioxo-beta,kappa-caroten-17'-al
No. 262 No. 59
C00029793 External link 512 Bastadin 13
C094710
No. 651
C00029799 External link 512 Bastadin 7
CHEMBL360190
23 / 29 / 31 No. 651
C00029798 External link 512 Bastadin 6
CHEMBL505907
CHEMBL510730
9 / 12 / 21 No. 651
C00029792 External link 512 Bastadin 11
CHEMBL2331573
No. 651
C00029797 External link 512 Bastadin 5
CHEMBL439151
C105188
1 / 4 / 2 No. 651
C00029794 External link 512 Bastadin 19
No. 651
C00029796 External link 512 Bastadin 4
CHEMBL453147
CHEMBL455487
1 / 4 / 2 No. 651
C00029795 External link 512 Bastadin 3
CHEMBL505637
26 / 27 / 30 No. 651
C00028338 External link 512 Hemibastadinol 1
CHEMBL450387
No. 3591
C00028340 External link 512 Hemibastadinol 3
No. 3591
C00028339 External link 512 Hemibastadinol 2
No. 3591

Human Protein / Gene in interactions

29 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P21817 Ryanodine receptor 1 CA C00029796 C00029797 C00029798 C00029799 4 / 2
P11802 Cyclin-dependent kinase 4 CMGC serine/threonine protein kinase family C00029795 C00029798 C00029799 1 / 3
P41279 Mitogen-activated protein kinase kinase kinase 8 Ste11 C00029795 C00029798 C00029799 0 / 0
Q96GD4 Aurora kinase B Aur C00029795 C00029798 C00029799 0 / 0
O14965 Aurora kinase A Aur C00029795 C00029798 C00029799 0 / 0
P24385 G1/S-specific cyclin-D1 Other cytosolic protein C00029795 C00029798 C00029799 1 / 8
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00029795 C00029798 C00029799 1 / 8
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00029795 C00029798 C00029799 1 / 1
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00029795 C00029798 C00029799 5 / 9
P08069 Insulin-like growth factor 1 receptor TK tyrosine-protein kinase INSR subfamily C00029795 C00029799 1 / 3
Q05397 Focal adhesion kinase 1 Fak C00029795 C00029799 0 / 0
Q02763 Angiopoietin-1 receptor Tie C00029795 C00029799 1 / 1
O60285 NUAK family SNF1-like kinase 1 CAMK serine/threonine protein kinase NUAK subfamily C00029795 C00029799 0 / 0
P06213 Insulin receptor TK tyrosine-protein kinase INSR subfamily C00029795 C00029799 5 / 4
P54760 Ephrin type-B receptor 4 Eph C00029795 C00029799 0 / 0
P09619 Platelet-derived growth factor receptor beta Pdgfr C00029795 C00029799 5 / 1
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00029795 C00029799 0 / 0
O00444 Serine/threonine-protein kinase PLK4 PLK serine/threonine protein kinase subfamily C00029795 C00029799 0 / 0
P35968 Vascular endothelial growth factor receptor 2 Vegfr C00029795 C00029799 1 / 0
P35916 Vascular endothelial growth factor receptor 3 Vegfr C00029795 C00029799 2 / 1
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily C00029795 C00029799 2 / 3
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00029799 2 / 0
P68400 Casein kinase II subunit alpha Ck2 C00029795 0 / 0
P53350 Serine/threonine-protein kinase PLK1 PLK serine/threonine protein kinase subfamily C00029795 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00029799 0 / 0
P31749 RAC-alpha serine/threonine-protein kinase Akt C00029795 4 / 1
P20248 Cyclin-A2 Other cytosolic protein C00029795 0 / 0
P78396 Cyclin-A1 Other cytosolic protein C00029795 0 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 C00029795 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (32)

OMIM preferred title UniProt
#615007 Basal ganglia calcification, idiopathic, 4; ibgc4 P09619
#114480 Breast cancer P31749
#117000 Central core disease of muscle P21817
#114500 Colorectal cancer; crc P18054
P31749
#615109 Cowden syndrome 6; cws6 P31749
#610549 Diabetes mellitus, insulin-resistant, with acanthosis nigricans P06213
#125853 Diabetes mellitus, noninsulin-dependent; niddm P06213
#246200 Donohue syndrome P06213
#133239 Esophageal cancer P18054
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#137800 Glioma susceptibility 1; glm1 P04626
#602089 Hemangioma, capillary infantile P35916
P35968
#114550 Hepatocellular carcinoma P08581
#609968 Hyperinsulinemic hypoglycemia, familial, 5; hhf5 P06213
#270450 Insulin-like growth factor i, resistance to P08069
#607785 Juvenile myelomonocytic leukemia; jmml P09619
#601626 Leukemia, acute myeloid; aml P09619
P36888
#211980 Lung cancer P00533
P04626
#153100 Lymphedema, hereditary, ia P35916
#145600 Malignant hyperthermia, susceptibility to, 1; mhs1 P21817
#609048 Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 P11802
#255320 Minicore myopathy with external ophthalmoplegia P21817
#254500 Myeloma, multiple P24385
#131440 Myeloproliferative disorder, chronic, with eosinophilia P09619
#228550 Myofibromatosis, infantile, 1; imf1 P09619
#255310 Myopathy, congenital, with fiber-type disproportion; cftd P21817
#167000 Ovarian cancer P04626
#262190 Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities P06213
#176920 Proteus syndrome P31749
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#600195 Venous malformations, multiple cutaneous and mucosal; vmcm Q02763

KEGG DISEASE (32)

KEGG name UniProt
H00016 Oral cancer P00533 (related)
P00533 (marker)
P24385 (related)
P24385 (marker)
H00017 Esophageal cancer P00533 (related)
P24385 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P08581 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
H00028 Choriocarcinoma P00533 (related)
P04626 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
P11802 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P09619 (related)
P11802 (related)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P24385 (related)
P24385 (marker)
H00019 Pancreatic cancer P04626 (related)
H00026 Endometrial Cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P24385 (related)
H00046 Cholangiocarcinoma P04626 (related)
P08581 (related)
H00719 Leprechaunism P06213 (related)
H00942 Rabson-Mendenhall syndrome P06213 (related)
H01228 Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) P06213 (related)
H01267 Familial hyperinsulinemic hypoglycemia (HHF) P06213 (related)
H00015 Malignant pleural mesothelioma P08069 (related)
H00050 Synovial sarcoma P08069 (related)
H01274 Growth delay due to insulin-like growth factor I resistance P08069 (related)
H00021 Renal cell carcinoma P08581 (related)
H00038 Malignant melanoma P11802 (related)
H00699 Central core disease P21817 (related)
H01310 Multi-minicore disease (MmD) P21817 (related)
H00006 Hairy-cell leukemia P24385 (related)
H00010 Multiple myeloma P24385 (related)
H00559 von Hippel-Lindau syndrome P24385 (related)
H00047 Gallbladder cancer P24385 (marker)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H00535 Lymphedemas P35916 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
H00531 Venous malformations Q02763 (related)