PCIDB

KNApSAcK Metabolite C00029798

Metabolite

KNApSAcK Entry

id C00029798
Name Bastadin 6
CAS RN 79067-74-6
Standard InChI InChI=1S/C34H26Br6N4O8/c35-19-5-16-2-4-42-33(47)25(43-49)11-17-9-23(39)32(24(40)10-17)52-28-14-18(8-20(36)30(28)46)12-26(44-50)34(48)41-3-1-15-6-21(37)31(22(38)7-15)51-27(13-16)29(19)45/h5-10,13-14,45-46,49-50H,1-4,11-12H2,(H,41,48)(H,42,47)/b43-25-,44-26+
Standard InChI (Main Layer) InChI=1S/C34H26Br6N4O8/c35-19-5-16-2-4-42-33(47)25(43-49)11-17-9-23(39)32(24(40)10-17)52-28-14-18(8-20(36)30(28)46)12-26(44-50)34(48)41-3-1-15-6-21(37)31(22(38)7-15)51-27(13-16)29(19)45/h5-10,13-14,45-46,49-50H,1-4,11-12H2,(H,41,48)(H,42,47)

Cluster

Phytochemical cluster
KCF-S cluster No. 651

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL505907 CHEMBL510730

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count

Family

family name count
Ianthellidae 2

List (3)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Ianthella basta 375146 Ianthellidae Metazoa
Ianthella quadrangulata 1162752 Ianthellidae Metazoa
Psammaplysilla purpurea

Human Protein / Gene in interaction

9 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
O14965 Aurora kinase A Aur CHEMBL510730 CHEMBL2344168 (1)
0 / 0
P11802 Cyclin-dependent kinase 4 CMGC serine/threonine protein kinase family CHEMBL510730 CHEMBL2344163 (1)
1 / 3
P24385 G1/S-specific cyclin-D1 Other cytosolic protein CHEMBL510730 CHEMBL2344163 (1)
1 / 10
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily CHEMBL510730 CHEMBL2344161 (1)
1 / 11
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr CHEMBL510730 CHEMBL2344158 (1)
1 / 1
P21817 Ryanodine receptor 1 CA CHEMBL505907 CHEMBL960265 (1)
4 / 2
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily CHEMBL510730 CHEMBL2344160 (1)
5 / 10
Q96GD4 Aurora kinase B Aur CHEMBL510730 CHEMBL2344167 (1)
0 / 0
P41279 Mitogen-activated protein kinase kinase kinase 8 Ste11 CHEMBL510730 CHEMBL2344162 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#117000 Central core disease of muscle P21817
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#137800 Glioma susceptibility 1; glm1 P04626
#601626 Leukemia, acute myeloid; aml P36888
#211980 Lung cancer P00533
P04626
#145600 Malignant hyperthermia, susceptibility to, 1; mhs1 P21817
#609048 Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 P11802
#255320 Minicore myopathy with external ophthalmoplegia P21817
#254500 Myeloma, multiple P24385
#255310 Myopathy, congenital, with fiber-type disproportion; cftd P21817
#167000 Ovarian cancer P04626

KEGG DISEASE (21)

KEGG disease name UniProt
H00016 Oral cancer P00533 (related)
P00533 (marker)
P24385 (related)
P24385 (marker)
H00017 Esophageal cancer P00533 (related)
P24385 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
H00028 Choriocarcinoma P00533 (related)
P04626 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
P11802 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P11802 (related)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P24385 (related)
P24385 (marker)
H00019 Pancreatic cancer P04626 (related)
H00026 Endometrial Cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P24385 (related)
H00046 Cholangiocarcinoma P04626 (related)
H00038 Malignant melanoma P11802 (related)
H00699 Central core disease P21817 (related)
H01310 Multi-minicore disease (MmD) P21817 (related)
H00006 Hairy-cell leukemia P24385 (related)
H00010 Multiple myeloma P24385 (related)
H00559 von Hippel-Lindau syndrome P24385 (related)
H00047 Gallbladder cancer P24385 (marker)
H00003 Acute myeloid leukemia (AML) P36888 (related)