PCIDB

Psammaplysilla purpurea

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	KCF-S cluster
C00029798	Bastadin 6	CHEMBL505907 CHEMBL510730		9 / 12 / 21	No. 651
C00038582	Bastadin 14	CHEMBL442828	C080231	2 / 1 / 1	No. 651
C00049628	Bastadin 16	CHEMBL2333164		6 / 7 / 18	No. 651
C00031112	Purpuramine H	CHEMBL462954			No. 832
C00049610	Aplysamine 2	CHEMBL465038 CHEMBL2062972			No. 832
C00038368	Aerothionin	CHEMBL228076 CHEMBL1999742			No. 1244
C00049665	Purealidin P				No. 1287
C00035953	5alpha,8alpha-Epidioxycholest-6-en-3beta-ol / (-)-5alpha,8alpha-Epidioxycholest-6-en-3beta-ol	CHEMBL453272			No. 2300
C00035927	3,5-Dibromo-4-methoxyphenylacetonitrile				No. 3215
C00035931	3-Bromo-4-methoxyphenylacetonitrile				No. 3215
C00031528	1-Hydroxyuracil				No. 3873
C00035930	3-Bromo-4-hydroxyphenylacetonitrile				No. 4008

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O14965	Aurora kinase A	Aur	C00029798 C00049628	0 / 0
P11802	Cyclin-dependent kinase 4	CMGC serine/threonine protein kinase family	C00029798 C00049628	1 / 3
P24385	G1/S-specific cyclin-D1	Other cytosolic protein	C00029798 C00049628	1 / 8
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00029798 C00049628	1 / 8
Q96GD4	Aurora kinase B	Aur	C00029798 C00049628	0 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00029798 C00049628	5 / 9
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00029798	1 / 1
P21817	Ryanodine receptor 1	CA	C00029798	4 / 2
P11388	DNA topoisomerase 2-alpha	Isomerase	C00038582	0 / 0
P41279	Mitogen-activated protein kinase kinase kinase 8	Ste11	C00029798	0 / 0
P00374	Dihydrofolate reductase	Oxidoreductase	C00038582	1 / 1

OMIM	preferred title	UniProt
#117000	Central core disease of muscle	P21817
#613659	Gastric cancer	P04626
#137215	Gastric cancer, hereditary diffuse; hdgc	P04626
#137800	Glioma susceptibility 1; glm1	P04626
#601626	Leukemia, acute myeloid; aml	P36888
#211980	Lung cancer	P00533 P04626
#145600	Malignant hyperthermia, susceptibility to, 1; mhs1	P21817
#613839	Megaloblastic anemia due to dihydrofolate reductase deficiency	P00374
#609048	Melanoma, cutaneous malignant, susceptibility to, 3; cmm3	P11802
#255320	Minicore myopathy with external ophthalmoplegia	P21817
#254500	Myeloma, multiple	P24385
#255310	Myopathy, congenital, with fiber-type disproportion; cftd	P21817
#167000	Ovarian cancer	P04626

KEGG	name	UniProt
H01197	Dihydrofolate reductase (DHFR) deficiency	P00374 (related)
H00016	Oral cancer	P00533 (related) P00533 (marker) P24385 (related) P24385 (marker)
H00017	Esophageal cancer	P00533 (related) P24385 (related)
H00018	Gastric cancer	P00533 (related) P04626 (related)
H00022	Bladder cancer	P00533 (related) P04626 (related)
H00028	Choriocarcinoma	P00533 (related) P04626 (related)
H00030	Cervical cancer	P00533 (related) P04626 (related) P11802 (related)
H00042	Glioma	P00533 (related) P00533 (marker) P11802 (related)
H00055	Laryngeal cancer	P00533 (related) P00533 (marker) P24385 (related) P24385 (marker)
H00019	Pancreatic cancer	P04626 (related)
H00026	Endometrial Cancer	P04626 (related)
H00027	Ovarian cancer	P04626 (related)
H00031	Breast cancer	P04626 (related) P04626 (marker) P24385 (related)
H00046	Cholangiocarcinoma	P04626 (related)
H00038	Malignant melanoma	P11802 (related)
H00699	Central core disease	P21817 (related)
H01310	Multi-minicore disease (MmD)	P21817 (related)
H00006	Hairy-cell leukemia	P24385 (related)
H00010	Multiple myeloma	P24385 (related)
H00559	von Hippel-Lindau syndrome	P24385 (related)
H00047	Gallbladder cancer	P24385 (marker)
H00003	Acute myeloid leukemia (AML)	P36888 (related)