KNApSAcK Metabolite C00049628
Metabolite
KNApSAcK Entry
| id | C00049628 |
|---|---|
| Name | Bastadin 16 |
| CAS RN | 156312-12-8 |
| Standard InChI | InChI=1S/C34H27Br5N4O8/c35-20-9-19-13-26(43-49)34(47)41-6-4-17-7-21(36)31(22(37)8-17)50-28-14-16(1-2-27(28)44)3-5-40-33(46)25(42-48)12-18-10-23(38)32(24(39)11-18)51-29(15-19)30(20)45/h1-2,7-11,14-15,44-45,48-49H,3-6,12-13H2,(H,40,46)(H,41,47)/b42-25+,43-26+ |
| Standard InChI (Main Layer) | InChI=1S/C34H27Br5N4O8/c35-20-9-19-13-26(43-49)34(47)41-6-4-17-7-21(36)31(22(37)8-17)50-28-14-16(1-2-27(28)44)3-5-40-33(46)25(42-48)12-18-10-23(38)32(24(39)11-18)51-29(15-19)30(20)45/h1-2,7-11,14-15,44-45,48-49H,3-6,12-13H2,(H,40,46)(H,41,47) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 651 |
Link
ChEMBL
| By standard InChI | CHEMBL2333164 |
|---|---|
| By standard InChI Main Layer | CHEMBL2333164 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Psammaplysilla purpurea |
Human Protein / Gene in interaction
6 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| O14965 | Aurora kinase A | Aur | CHEMBL2333164 |
CHEMBL2344168
(1)
|
0 / 0 |
| P11802 | Cyclin-dependent kinase 4 | CMGC serine/threonine protein kinase family | CHEMBL2333164 |
CHEMBL2344163
(1)
|
1 / 3 |
| P24385 | G1/S-specific cyclin-D1 | Other cytosolic protein | CHEMBL2333164 |
CHEMBL2344163
(1)
|
1 / 10 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | CHEMBL2333164 |
CHEMBL2344161
(1)
|
1 / 11 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | CHEMBL2333164 |
CHEMBL2344160
(1)
|
5 / 10 |
| Q96GD4 | Aurora kinase B | Aur | CHEMBL2333164 |
CHEMBL2344167
(1)
|
0 / 0 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (7)
| OMIM | preferred title | UniProt |
|---|---|---|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #137800 | Glioma susceptibility 1; glm1 |
P04626
|
| #211980 | Lung cancer |
P00533
P04626 |
| #609048 | Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 |
P11802
|
| #254500 | Myeloma, multiple |
P24385
|
| #167000 | Ovarian cancer |
P04626
|
KEGG DISEASE (18)
| KEGG | disease name | UniProt |
|---|---|---|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P24385 (related) P24385 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P24385 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P04626 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) P11802 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P11802 (related) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P24385 (related) P24385 (marker) |
| H00019 | Pancreatic cancer |
P04626
(related)
|
| H00026 | Endometrial Cancer |
P04626
(related)
|
| H00027 | Ovarian cancer |
P04626
(related)
|
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P24385 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
|
| H00038 | Malignant melanoma |
P11802
(related)
|
| H00006 | Hairy-cell leukemia |
P24385
(related)
|
| H00010 | Multiple myeloma |
P24385
(related)
|
| H00559 | von Hippel-Lindau syndrome |
P24385
(related)
|
| H00047 | Gallbladder cancer |
P24385
(marker)
|