PCIDB

KNApSAcK Metabolite C00031336

Index

Metabolite

Species

Human Protein
/ Gene in interactions

Related Diseases

Metabolite

KNApSAcK Entry

id	C00031336
Name	Scutellaric acid / (+)-Scutellaric acid
CAS RN	102919-76-6
Standard InChI	InChI=1S/C30H48O4/c1-25(2)13-15-30(24(33)34)16-14-28(5)19(20(30)17-25)7-8-22-26(3)11-10-23(32)27(4,18-31)21(26)9-12-29(22,28)6/h7,20-23,31-32H,8-18H2,1-6H3,(H,33,34)/t20-,21+,22+,23+,26-,27+,28+,29+,30-/m0/s1
Standard InChI (Main Layer)	InChI=1S/C30H48O4/c1-25(2)13-15-30(24(33)34)16-14-28(5)19(20(30)17-25)7-8-22-26(3)11-10-23(32)27(4,18-31)21(26)9-12-29(22,28)6/h7,20-23,31-32H,8-18H2,1-6H3,(H,33,34)

Cluster

Phytochemical cluster	No. 51
KCF-S cluster	No. 13

Link

ChEMBL

By standard InChI	CHEMBL492472
By standard InChI Main Layer	CHEMBL486400 CHEMBL492472 CHEMBL1436053

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name	count
asterids	2

Family

family name	count
Rubiaceae	1
Gesneriaceae	1

List (2)

* NCBI

KNApSAcK organism	*ID	*family	*plant class	*kingdom
Conandron ramondioides Sieb.et Zucc.	121478	Gesneriaceae	asterids	Viridiplantae
Coussarea brevicaulis	564779	Rubiaceae	asterids	Viridiplantae

Human Protein / Gene in interaction

7 ChEMBL Protein in interactions

accession	description	class description	compound	assay ID (# of activities)	# of diseases (OMIM / KEGG)
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	CHEMBL492472	CHEMBL1036591 (1)	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	CHEMBL1436053	CHEMBL1614331 (1)	0 / 0
P02545	Prelamin-A/C	Unclassified protein	CHEMBL1436053	CHEMBL1614544 (1)	11 / 10
P08047	Transcription factor Sp1	Unclassified protein	CHEMBL492472	CHEMBL1058704 (1)	0 / 0
P15559	NAD(P)H dehydrogenase [quinone] 1	Enzyme	CHEMBL486400	CHEMBL1004305 (1)	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	CHEMBL1436053	CHEMBL1614108 (1) CHEMBL1613886 (1)	0 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	CHEMBL1436053	CHEMBL1794536 (1)	0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM	preferred title	UniProt
#115200	Cardiomyopathy, dilated, 1a; cmd1a	P02545
#212112	Cardiomyopathy, dilated, with hypergonadotropic hypogonadism	P02545
#605588	Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1	P02545
#181350	Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2	P02545
#610140	Heart-hand syndrome, slovenian type	P02545
#176670	Hutchinson-gilford progeria syndrome; hgps	P02545
#151660	Lipodystrophy, familial partial, type 2; fpld2	P02545
#248370	Mandibuloacral dysplasia with type a lipodystrophy; mada	P02545
#613205	Muscular dystrophy, congenital, lmna-related	P02545
#159001	Muscular dystrophy, limb-girdle, type 1b; lgmd1b	P02545
#275210	Restrictive dermopathy, lethal	P02545

KEGG DISEASE (11)

KEGG	disease name	UniProt
H00264	Charcot-Marie-Tooth disease (CMT)	P02545 (related)
H00294	Dilated cardiomyopathy (DCM)	P02545 (related)
H00420	Familial partial lipodystrophy (FPL)	P02545 (related)
H00563	Emery-Dreifuss muscular dystrophy	P02545 (related)
H00590	Congenital muscular dystrophies (CMD/MDC)	P02545 (related)
H00593	Limb-girdle muscular dystrophy (LGMD)	P02545 (related)
H00601	Hutchinson-Gilford progeria syndrome	P02545 (related)
H00663	Restrictive dermopathy	P02545 (related)
H00665	Mandibuloacral dysplasia	P02545 (related)
H01216	Left ventricular noncompaction (LVNC)	P02545 (related)
H00036	Osteosarcoma	P08684 (marker)