PCIDB

KNApSAcK Metabolite C00003218

Metabolite

KNApSAcK Entry

id C00003218
Name Aromaticin
CAS RN 5945-42-6
Standard InChI InChI=1S/C15H18O3/c1-8-6-12-10(9(2)14(17)18-12)7-15(3)11(8)4-5-13(15)16/h4-5,8,10-12H,2,6-7H2,1,3H3/t8-,10-,11+,12+,15+/m1/s1
Standard InChI (Main Layer) InChI=1S/C15H18O3/c1-8-6-12-10(9(2)14(17)18-12)7-15(3)11(8)4-5-13(15)16/h4-5,8,10-12H,2,6-7H2,1,3H3

Cluster

Phytochemical cluster No. 38
KCF-S cluster No. 495

Link

ChEMBL

By standard InChI CHEMBL494255
By standard InChI Main Layer CHEMBL494255

KEGG

By LinkDB C09300

CTD

By CAS RN

Species

Summary

Plant class

class name count
asterids 2

Family

family name count
Asteraceae 2

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Helenium amarum 289417 Asteraceae asterids Viridiplantae
Helenium aromaticum 53720 Asteraceae asterids Viridiplantae

Human Protein / Gene in interaction

15 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P17861 X-box-binding protein 1 Unclassified protein CHEMBL494255 CHEMBL1738682 (1)
1 / 0
Q99700 Ataxin-2 Unclassified protein CHEMBL494255 CHEMBL2114784 (1)
1 / 1
P42858 Huntingtin Unclassified protein CHEMBL494255 CHEMBL1613918 (1)
1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL494255 CHEMBL1794584 (1)
2 / 0
O75496 Geminin Unclassified protein CHEMBL494255 CHEMBL2114843 (1) CHEMBL2114780 (1)
0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein CHEMBL494255 CHEMBL1613838 (1)
0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL494255 CHEMBL2114788 (1)
0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme CHEMBL494255 CHEMBL1963863 (1)
0 / 0
Q00987 E3 ubiquitin-protein ligase Mdm2 Other nuclear protein CHEMBL494255 CHEMBL1613898 (1)
1 / 5
O15118 Niemann-Pick C1 protein Unclassified protein CHEMBL494255 CHEMBL1614342 (1)
1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL494255 CHEMBL1738588 (1) CHEMBL1738317 (1)
0 / 0
Q9UNA4 DNA polymerase iota Enzyme CHEMBL494255 CHEMBL1794483 (1)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL494255 CHEMBL1614250 (1) CHEMBL1614421 (1)
4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL494255 CHEMBL1738184 (1)
0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL494255 CHEMBL2354311 (1)
1 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#614401 Accelerated tumor formation, susceptibility to; actfs Q00987
#114500 Colorectal cancer; crc P84022
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#143100 Huntington disease; hd P42858
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#612371 Major affective disorder 7; mafd7 P17861
#257220 Niemann-pick disease, type c1; npc1 O15118
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (11)

KEGG disease name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00025 Penile cancer Q00987 (related)
H00028 Choriocarcinoma Q00987 (related)
H00036 Osteosarcoma Q00987 (related)
H00037 Alveolar rhabdomyosarcoma Q00987 (related)
H00042 Glioma Q00987 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)