KNApSAcK Metabolite C00003221
Metabolite
KNApSAcK Entry
| id | C00003221 |
|---|---|
| Name | (-)-Artemisin / 8-Hydroxysantonin / [3S-(3alpha,3aalpha,4alpha,5abeta,9bbeta)]-3a,5,5a,9b-Tetrahydro-4-hydroxy-3,5a,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)-dione |
| CAS RN | 481-05-0 |
| Standard InChI | InChI=1S/C15H18O4/c1-7-9(16)4-5-15(3)6-10(17)11-8(2)14(18)19-13(11)12(7)15/h4-5,8,10-11,13,17H,6H2,1-3H3/t8-,10-,11+,13-,15+/m0/s1 |
| Standard InChI (Main Layer) | InChI=1S/C15H18O4/c1-7-9(16)4-5-15(3)6-10(17)11-8(2)14(18)19-13(11)12(7)15/h4-5,8,10-11,13,17H,6H2,1-3H3 |
Cluster
| Phytochemical cluster | No. 38 |
|---|---|
| KCF-S cluster | No. 2117 |
Link
ChEMBL
| By standard InChI | CHEMBL158124 |
|---|---|
| By standard InChI Main Layer | CHEMBL158124 CHEMBL1673435 |
KEGG
| By LinkDB | C09344 |
|---|
CTD
| By CAS RN | C075875 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| asterids | 3 |
Family
| family name | count |
|---|---|
| Asteraceae | 3 |
List (3)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Artemisia cina | 4219 | Asteraceae | asterids | Viridiplantae |
| Artemisia macrocephala | 1227631 | Asteraceae | asterids | Viridiplantae |
| Artemisia maritima | 669130 | Asteraceae | asterids | Viridiplantae |
Human Protein / Gene in interaction
1 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | CHEMBL1673435 |
CHEMBL1676103
(1)
|
2 / 2 |
CTD interaction (1)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C075875 | 1544 |
CYP1A2
CP12 P3-450 P450(PA) |
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) | artemisin results in decreased activity of CYP1A2 protein |
decreases activity
|
protein |
16261361
|