KCF-S cluster No. 2117 (5 metabolites)

Corresponding Phytochemical cluster No. 38

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (5)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	11

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Cumulative family count

class name	count
Asteraceae	11

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Eudesmanes	3

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metabolites link (3)

br08003 Category	KEGG ID	KNApSAcK ID
Eudesmanes	C09344	C00003221
Eudesmanes	C02206	C00003364
Eudesmanes	C09545	C00003365

Metabolite list (5)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00003221	(-)-Artemisin / 8-Hydroxysantonin / [3S-(3alpha,3aalpha,4alpha,5abeta,9bbeta)]-3a,5,5a,9b-Tetrahydro-4-hydroxy-3,5a,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)-dione	CHEMBL158124 CHEMBL1673435	C075875	1 / 2 / 2	1 / 0
C00003364	Semenen / Santonin / a-Santonin / (-)-Santonin / (-)-alpha-Santonin / [3S-(3alpha,3aalpha,5abeta,9bbeta)]-3a,5,5a,9b-Tetrahydro-3,5a,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)-dione	CHEMBL226231 CHEMBL259254 CHEMBL1357930 CHEMBL1570028 CHEMBL1600999 CHEMBL1717567 CHEMBL2103785	D012500	14 / 11 / 8
C00003365	beta-Santonin / [3R-(3alpha,3abeta,5aalpha,9balpha)]-3a,5,5a,9b-Tetrahydro-3,5a,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)-dione	CHEMBL226231 CHEMBL259254 CHEMBL1357930 CHEMBL1570028 CHEMBL1600999 CHEMBL1717567 CHEMBL2103785		14 / 11 / 8
C00013078	Tubiferin / Tuberiferin / (+)-Tuberiferine / [3aS-(3aalpha,5abeta,9alpha,9aalpha,9bbeta)]-3a,5,5a,9,9a,9b-Hexahydro-5a,9-dimethyl-3-methylenenaphtho[1,2-b]furan-2,8(3H,4H)-dione
C00021439	6,7,9,10-Tetradehydroasteriscanolide

Human Protein / Gene in interactions

15 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00003364 C00003365	1 / 0
Q99700	Ataxin-2	Unclassified protein	C00003364 C00003365	1 / 1
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00003364 C00003365	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00003364 C00003365	1 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00003364 C00003365	0 / 1
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00003364 C00003365	0 / 0
O75496	Geminin	Unclassified protein	C00003364 C00003365	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00003364 C00003365	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00003364 C00003365	0 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00003364 C00003365	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00003364 C00003365	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00003364 C00003365	0 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00003364 C00003365	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00003364 C00003365	7 / 3
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00003221	2 / 2

1 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00003221

Related Diseases

Diseases related to proteins in ChEMBL interactions