KNApSAcK Metabolite C00032791
Metabolite
KNApSAcK Entry
| id | C00032791 |
|---|---|
| Name | Olomoucin / Butyrolactone I |
| CAS RN | 87414-49-1 |
| Standard InChI | InChI=1S/C24H24O7/c1-14(2)4-6-17-12-15(5-11-19(17)26)13-24(23(29)30-3)20(21(27)22(28)31-24)16-7-9-18(25)10-8-16/h4-5,7-12,25-27H,6,13H2,1-3H3/t24-/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C24H24O7/c1-14(2)4-6-17-12-15(5-11-19(17)26)13-24(23(29)30-3)20(21(27)22(28)31-24)16-7-9-18(25)10-8-16/h4-5,7-12,25-27H,6,13H2,1-3H3 |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 1559 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer | CHEMBL1242973 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN | C082868 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Aspergillaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Aspergillus terreus DRCC 152 | 5052 | Aspergillaceae | Fungi |
Human Protein / Gene in interaction
9 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | CHEMBL1242973 |
CHEMBL657124
(1)
CHEMBL1250281
(1)
|
0 / 0 |
| P06493 | Cyclin-dependent kinase 1 | Cdc2 | CHEMBL1242973 |
CHEMBL661114
(1)
CHEMBL1246065
(1)
CHEMBL1250280 (1) |
0 / 0 |
| P14635 | G2/mitotic-specific cyclin-B1 | Other cytosolic protein | CHEMBL1242973 |
CHEMBL661114
(1)
CHEMBL1246065
(1)
|
0 / 0 |
| P11802 | Cyclin-dependent kinase 4 | CMGC serine/threonine protein kinase family | CHEMBL1242973 |
CHEMBL666302
(1)
CHEMBL1250276
(1)
|
1 / 3 |
| P24385 | G1/S-specific cyclin-D1 | Other cytosolic protein | CHEMBL1242973 |
CHEMBL666302
(1)
|
1 / 10 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | CHEMBL1242973 |
CHEMBL873605
(1)
|
1 / 11 |
| Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | CMGC dual-specificity kinase DYRK1 | CHEMBL1242973 |
CHEMBL980537
(1)
|
1 / 0 |
| P24864 | G1/S-specific cyclin-E1 | Other cytosolic protein | CHEMBL1242973 |
CHEMBL657124
(1)
|
0 / 2 |
| O96020 | G1/S-specific cyclin-E2 | Other cytosolic protein | CHEMBL1242973 |
CHEMBL657124
(1)
|
0 / 2 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (4)
| OMIM | preferred title | UniProt |
|---|---|---|
| #211980 | Lung cancer |
P00533
|
| #609048 | Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 |
P11802
|
| #614104 | Mental retardation, autosomal dominant 7; mrd7 |
Q13627
|
| #254500 | Myeloma, multiple |
P24385
|
KEGG DISEASE (14)
| KEGG | disease name | UniProt |
|---|---|---|
| H00018 | Gastric cancer |
O96020
(related)
P00533 (related) P24864 (related) |
| H00055 | Laryngeal cancer |
O96020
(related)
P00533 (related) P00533 (marker) P24385 (related) P24385 (marker) P24864 (related) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P24385 (related) P24385 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P24385 (related) |
| H00022 | Bladder cancer |
P00533
(related)
|
| H00028 | Choriocarcinoma |
P00533
(related)
|
| H00030 | Cervical cancer |
P00533
(related)
P11802 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P11802 (related) |
| H00038 | Malignant melanoma |
P11802
(related)
|
| H00006 | Hairy-cell leukemia |
P24385
(related)
|
| H00010 | Multiple myeloma |
P24385
(related)
|
| H00031 | Breast cancer |
P24385
(related)
|
| H00559 | von Hippel-Lindau syndrome |
P24385
(related)
|
| H00047 | Gallbladder cancer |
P24385
(marker)
|