| class name | count |
|---|
| class name | count |
|---|---|
| Aspergillaceae | 7 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00032791
|
Olomoucin
/ Butyrolactone I |
CHEMBL1242973
|
C082868
|
9 / 4 / 14 |
|
|
|
C00032792
|
Butyrolactone II
|
CHEMBL1542814
|
19 / 12 / 12 |
|
||
|
C00032793
|
Butyrolactone IV
/ (+)-Butyrolactone IV |
CHEMBL2035562
|
|
|||
|
C00038667
|
Butyrolactone I 3-sulfate
|
CHEMBL460464
|
1 / 1 / 0 |
|
||
|
C00038668
|
Butyrolactone I 4''-sulfate
/ (+)-Butyrolactone I 4''-sulfate |
CHEMBL465047
|
1 / 1 / 0 |
|
||
|
C00048321
|
Aspernolide A
/ (+)-Aspernolide A |
|
||||
|
C00048322
|
Aspernolide B
/ (+)-Aspernolide B |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | CMGC dual-specificity kinase DYRK1 | C00032791 C00038667 C00038668 | 1 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00032792 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00032792 | 1 / 1 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00032791 | 0 / 0 |
| P06493 | Cyclin-dependent kinase 1 | Cdc2 | C00032791 | 0 / 0 |
| P14635 | G2/mitotic-specific cyclin-B1 | Other cytosolic protein | C00032791 | 0 / 0 |
| P11802 | Cyclin-dependent kinase 4 | CMGC serine/threonine protein kinase family | C00032791 | 1 / 3 |
| P24385 | G1/S-specific cyclin-D1 | Other cytosolic protein | C00032791 | 1 / 8 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00032792 | 1 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00032791 | 1 / 8 |
| P39748 | Flap endonuclease 1 | Enzyme | C00032792 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00032792 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00032792 | 1 / 1 |
| P51843 | Nuclear receptor subfamily 0 group B member 1 | Nuclear hormone receptor subfamily 0 group B member 1 | C00032792 | 2 / 2 |
| P06746 | DNA polymerase beta | Enzyme | C00032792 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00032792 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00032792 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00032792 | 4 / 3 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00032792 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00032792 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00032792 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00032792 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00032792 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00032792 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00032792 | 1 / 4 |
| P24864 | G1/S-specific cyclin-E1 | Other cytosolic protein | C00032791 | 0 / 2 |
| O96020 | G1/S-specific cyclin-E2 | Other cytosolic protein | C00032791 | 0 / 2 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00032792 | 2 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #300018 | 46,xy sex reversal 2; srxy2 |
P51843
|
| #300200 | Adrenal hypoplasia, congenital; ahc |
P51843
|
| #114500 | Colorectal cancer; crc |
Q14191
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #211980 | Lung cancer |
P00533
|
| #609048 | Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 |
P11802
|
| #614104 | Mental retardation, autosomal dominant 7; mrd7 |
Q13627
|
| #254500 | Myeloma, multiple |
P24385
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00018 | Gastric cancer |
O96020
(related)
P00533 (related) P24864 (related) |
| H00055 | Laryngeal cancer |
O96020
(related)
P00533 (related) P00533 (marker) P24385 (related) P24385 (marker) P24864 (related) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P24385 (related) P24385 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P24385 (related) |
| H00022 | Bladder cancer |
P00533
(related)
|
| H00028 | Choriocarcinoma |
P00533
(related)
|
| H00030 | Cervical cancer |
P00533
(related)
P11802 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P11802 (related) |
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00038 | Malignant melanoma |
P11802
(related)
|
| H00006 | Hairy-cell leukemia |
P24385
(related)
|
| H00010 | Multiple myeloma |
P24385
(related)
|
| H00031 | Breast cancer |
P24385
(related)
|
| H00559 | von Hippel-Lindau syndrome |
P24385
(related)
|
| H00047 | Gallbladder cancer |
P24385
(marker)
|
| H00552 | Glycerol kinase deficiency (GKD) |
P51843
(related)
|
| H00607 | 46,XY disorders of sex development (Disorders of gonadal development) |
P51843
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|