PCIDB

KNApSAcK Metabolite C00034669

Metabolite

KNApSAcK Entry

id C00034669
Name Salvinorin A
CAS RN 83729-01-5
Standard InChI InChI=1S/C23H28O8/c1-12(24)30-16-9-15(20(26)28-4)22(2)7-5-14-21(27)31-17(13-6-8-29-11-13)10-23(14,3)19(22)18(16)25/h6,8,11,14-17,19H,5,7,9-10H2,1-4H3/t14-,15-,16-,17-,19-,22-,23-/m0/s1
Standard InChI (Main Layer) InChI=1S/C23H28O8/c1-12(24)30-16-9-15(20(26)28-4)22(2)7-5-14-21(27)31-17(13-6-8-29-11-13)10-23(14,3)19(22)18(16)25/h6,8,11,14-17,19H,5,7,9-10H2,1-4H3

Cluster

Phytochemical cluster No. 43
KCF-S cluster No. 4174

Link

ChEMBL

By standard InChI CHEMBL445332
By standard InChI Main Layer CHEMBL178960 CHEMBL445332 CHEMBL435108 CHEMBL193735 CHEMBL378767 CHEMBL458235

KEGG

By LinkDB C20196

CTD

By CAS RN C090499

Species

Summary

Plant class

class name count
asterids 1

Family

family name count
Lamiaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Salvia divinorum 28513 Lamiaceae asterids Viridiplantae

Human Protein / Gene in interaction

9 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P11473 Vitamin D3 receptor NR1I1 CHEMBL445332 CHEMBL1794311 (1)
2 / 3
P41145 Kappa-type opioid receptor Opioid receptor CHEMBL178960 CHEMBL445332 CHEMBL435108 CHEMBL193735 CHEMBL378767 CHEMBL458235 CHEMBL876690 (2) CHEMBL839506 (2)
CHEMBL839963 (1) CHEMBL828942 (2)
CHEMBL829775 (1) CHEMBL832509 (1)
CHEMBL831057 (1) CHEMBL835608 (2)
CHEMBL836225 (1) CHEMBL830739 (1)
CHEMBL830746 (2) CHEMBL832135 (1)
CHEMBL910349 (4) CHEMBL910350 (4)
CHEMBL910351 (4) CHEMBL909560 (1)
CHEMBL909561 (1) CHEMBL909562 (1)
CHEMBL887467 (4) CHEMBL890208 (2)
CHEMBL890209 (1) CHEMBL900508 (1)
CHEMBL900509 (1) CHEMBL946804 (1)
CHEMBL946807 (1) CHEMBL946808 (1)
CHEMBL923552 (2) CHEMBL935623 (1)
CHEMBL935624 (1) CHEMBL988701 (2)
CHEMBL988702 (2) CHEMBL988703 (2)
CHEMBL968095 (1) CHEMBL969921 (2)
CHEMBL969922 (2) CHEMBL969923 (2)
CHEMBL969924 (2) CHEMBL969925 (2)
CHEMBL969926 (2) CHEMBL1071835 (1)
CHEMBL1168405 (1) CHEMBL1260356 (1)
CHEMBL1260357 (1) CHEMBL1260359 (1)
CHEMBL1648968 (1) CHEMBL1648971 (2)
CHEMBL1775888 (1) CHEMBL1775891 (1)
CHEMBL1775892 (1) CHEMBL1942428 (1)
CHEMBL1942429 (2) CHEMBL1942558 (2)
CHEMBL1942559 (2) CHEMBL1942560 (1)
CHEMBL1942563 (2) CHEMBL1942565 (2)
CHEMBL2026564 (2) CHEMBL2026571 (2)
CHEMBL2026574 (2) CHEMBL2026577 (1)
CHEMBL2026578 (1)
0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL445332 CHEMBL1738606 (1)
0 / 0
P41143 Delta-type opioid receptor Opioid receptor CHEMBL445332 CHEMBL378767 CHEMBL458235 CHEMBL839505 (2) CHEMBL829297 (1)
CHEMBL831062 (1) CHEMBL830746 (2)
CHEMBL890207 (1) CHEMBL923551 (2)
CHEMBL968094 (1) CHEMBL969928 (2)
CHEMBL1648967 (1) CHEMBL1775886 (1)
CHEMBL2026568 (2) CHEMBL2026570 (1)
0 / 0
P35372 Mu-type opioid receptor Opioid receptor CHEMBL445332 CHEMBL378767 CHEMBL458235 CHEMBL838703 (2) CHEMBL830098 (1)
CHEMBL831061 (1) CHEMBL830739 (1)
CHEMBL832135 (1) CHEMBL890206 (1)
CHEMBL923550 (2) CHEMBL923555 (1)
CHEMBL923556 (1) CHEMBL968093 (1)
CHEMBL969927 (2) CHEMBL1648966 (1)
CHEMBL1775893 (1) CHEMBL1775894 (1)
CHEMBL2026565 (2) CHEMBL2026566 (1)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL445332 CHEMBL1738442 (1)
0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme CHEMBL445332 CHEMBL1614364 (2)
1 / 1
Q13951 Core-binding factor subunit beta Unclassified protein CHEMBL445332 CHEMBL1613933 (1)
0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein CHEMBL445332 CHEMBL1613933 (1)
1 / 6

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (8)

KEGG disease name UniProt
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)

Diseases related to CTD interactions

3 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D019970 C090499 Cocaine-Related Disorders therapeutic
19747933
D007859 C090499 Learning Disorders marker/mechanism
21960665
D008569 C090499 Memory Disorders marker/mechanism
21960665