Salvia divinorum
Species
KNApSAcK Entry
| Organism name | Salvia divinorum |
|---|---|
| Genus | Salvia |
| Family | Labiatae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Salvia divinorum |
|---|---|
| Linked NCBI taxonomy ID | 28513 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Lamiaceae |
|---|---|
| ID | 4136 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Natural Activity
List (12)
| Species | Activity |
|---|---|
| Salvia divinorum Epling & Jativa | Anticholinergic |
| Salvia divinorum Epling & Jativa | Depressant |
| Salvia divinorum Epling & Jativa | Emetic |
| Salvia divinorum Epling & Jativa | Emetic |
| Salvia divinorum Epling & Jativa | Hallucinogen |
| Salvia divinorum Epling & Jativa | Hallucinogenic |
| Salvia divinorum Epling & Jativa | Narcotic |
| Salvia divinorum Epling & Jativa | Narcotic |
| Salvia divinorum Epling & Jativa | Psychotropic |
| Salvia divinorum Epling & Jativa | Psychotropic |
| Salvia divinorum Epling & Jativa | Telepathic |
| Salvia divinorum Epling & Jativa | Telepathic |
Metabolite list (21)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00047346
|
Salvinorin G
/ (-)-Salvinorin G |
No. 731 |
|
|||||
|
C00041826
|
Salvinorin H
/ (+)-Salvinorin H |
No. 731 |
|
|||||
|
C00041825
|
Salvinorin E
/ (+)-Salvinorin E |
CHEMBL194708
|
No. 731 |
|
||||
|
C00041823
|
Salvinorin C
/ (+)-Salvinorin C |
CHEMBL365547
|
No. 731 |
|
||||
|
C00034671
|
Salvinorin F
/ (-)-Salvinorin F |
No. 731 |
|
|||||
|
C00041824
|
Salvinorin D
/ (+)-Salvinorin D |
CHEMBL191597
|
No. 731 |
|
||||
|
C00047217
|
Divinatorin E
/ (-)-Divinatorin E |
No. 941 |
|
|||||
|
C00047216
|
Divinatorin D
/ (-)-Divinatorin D |
No. 941 |
|
|||||
|
C00041507
|
Divinorin F
/ (+)-Divinorin F |
No. 941 |
|
|||||
|
C00034484
|
Divinatorin B
/ (-)-Divinatorin B |
CHEMBL511902
|
No. 941 |
|
||||
|
C00034483
|
Divinatorin A
/ (-)-Divinatorin A |
CHEMBL466786
|
No. 982 |
|
||||
|
C00044725
|
Divinatorin C
/ (-)-Divinatorin C |
CHEMBL466787
|
No. 2536 |
|
||||
|
C00041822
|
Salvidivin C
/ (-)-Salvidivin C |
No. 2626 |
|
|||||
|
C00041821
|
Salvidivin B
/ (-)-Salvidivin B |
No. 2626 |
|
|||||
|
C00047343
|
Salvidivin D
/ (-)-Salvidivin D |
No. 2626 |
|
|||||
|
C00041820
|
Salvidivin A
/ (-)-Salvidivin A |
CHEMBL226943
|
3 / 0 / 0 | No. 2626 |
|
|||
|
C00034669
|
Salvinorin A
|
CHEMBL178960
CHEMBL445332 CHEMBL435108 CHEMBL193735 CHEMBL378767 CHEMBL458235 |
C090499
|
9 / 4 / 8 | 0 / 3 | No. 4174 | No. 43 |
|
|
C00034670
|
Salvinorin B
/ (-)-Salvinorin B |
CHEMBL178129
CHEMBL194982 CHEMBL212385 CHEMBL424698 CHEMBL1941032 |
3 / 0 / 0 | No. 4174 | No. 43 |
|
||
|
C00047345
|
Salvinicin B
/ (-)-Salvinicin B |
CHEMBL560302
CHEMBL550433 |
3 / 0 / 0 | No. 5557 |
|
|||
|
C00047344
|
Salvinicin A
/ (-)-Salvinicin A |
CHEMBL560302
CHEMBL550433 |
3 / 0 / 0 | No. 5557 |
|
|||
|
C00041827
|
Salvinorin I
/ (-)-Salvinorin I |
No. 8548 |
|
Human Protein / Gene in interactions
9 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P35372 | Mu-type opioid receptor | Opioid receptor | C00034669 C00034670 C00041820 C00047344 C00047345 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00034669 C00034670 C00041820 C00047344 C00047345 | 0 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00034669 C00034670 C00041820 C00047344 C00047345 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00034669 | 2 / 3 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00034669 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00034669 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00034669 | 1 / 1 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00034669 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00034669 | 1 / 4 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (4)
| OMIM | preferred title | UniProt |
|---|---|---|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (8)
| KEGG | name | UniProt |
|---|---|---|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|