KNApSAcK Metabolite C00035480
Metabolite
KNApSAcK Entry
| id | C00035480 |
|---|---|
| Name | 2-Hexenal |
| CAS RN | 505-57-7 |
| Standard InChI | InChI=1S/C6H10O/c1-2-3-4-5-6-7/h4-6H,2-3H2,1H3/b5-4+ |
| Standard InChI (Main Layer) | InChI=1S/C6H10O/c1-2-3-4-5-6-7/h4-6H,2-3H2,1H3 |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 2883 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer |
KEGG
| By LinkDB | C08497 |
|---|
CTD
| By CAS RN | C051750 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| Liliopsida | 1 |
Family
| family name | count |
|---|---|
| Poaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Capillipedium parviflorum | 79829 | Poaceae | Liliopsida | Viridiplantae |
Human Protein / Gene in interaction
CTD interaction (12)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C051750 | 231 |
AKR1B1
ADR ALDR1 ALR2 AR |
aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) | AKR1B1 protein affects the reduction of 2-hexenal |
affects reduction
|
protein |
11306073
|
| C051750 | 231 |
AKR1B1
ADR ALDR1 ALR2 AR |
aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) | AKR1B1 protein results in increased reduction of 2-hexenal |
increases reduction
|
protein |
9890881
21329684 |
| C051750 | 231 |
AKR1B1
ADR ALDR1 ALR2 AR |
aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) | AKR1B1 protein results in increased reduction of 2-hexenal metabolite |
increases reduction
|
protein |
21329684
|
| C051750 | 57016 |
AKR1B10
AKR1B11 AKR1B12 ALDRLn ARL-1 ARL1 HIS HSI |
aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2) | AKR1B10 protein results in increased reduction of 2-hexenal |
increases reduction
|
protein |
21329684
|
| C051750 | 57016 |
AKR1B10
AKR1B11 AKR1B12 ALDRLn ARL-1 ARL1 HIS HSI |
aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2) | AKR1B10 protein results in increased reduction of 2-hexenal metabolite |
increases reduction
|
protein |
21329684
|
| C051750 | 1646 |
AKR1C2
AKR1C-pseudo BABP DD DD2 DDH2 HAKRD HBAB MCDR2 SRXY8 |
aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357) | 2-hexenal results in increased expression of AKR1C2 mRNA |
increases expression
|
mRNA |
20491607
|
| C051750 | 218 |
ALDH3A1
ALDH3 ALDHIII |
aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5) | ALDH3A1 protein affects the metabolism of 2-hexenal |
affects metabolic processing
|
protein |
11306050
|
| C051750 | 218 |
ALDH3A1
ALDH3 ALDHIII |
aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5) | ALDH3A1 protein results in decreased susceptibility to 2-hexenal |
decreases response to substance
|
protein |
11306050
|
| C051750 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | 2-hexenal results in increased expression of CYP1A1 mRNA |
increases expression
|
mRNA |
20491607
|
| C051750 | 2950 |
GSTP1
DFN7 FAEES3 GST3 GSTP PI |
glutathione S-transferase pi 1 (EC:2.5.1.18) | 2-hexenal binds to and results in decreased activity of GSTP1 protein |
affects binding
/ decreases activity |
protein |
9463521
|
| C051750 | 3162 |
HMOX1
HMOX1D HO-1 HSP32 bK286B10 |
heme oxygenase (decycling) 1 (EC:1.14.99.3) | 2-hexenal results in increased expression of HMOX1 mRNA |
increases expression
|
mRNA |
20491607
|
| C051750 | 23764 |
MAFF
U-MAF hMafF |
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 2-hexenal results in increased expression of MAFF mRNA |
increases expression
|
mRNA |
20491607
|