PCIDB

KNApSAcK Metabolite C00035996

Metabolite

KNApSAcK Entry

id C00035996
Name 10-Deacetylcephalomannine
CAS RN 76429-85-1
Standard InChI InChI=1S/C43H51NO13/c1-8-22(2)37(50)44-31(25-15-11-9-12-16-25)33(48)39(52)55-27-20-43(53)36(56-38(51)26-17-13-10-14-18-26)34-41(7,35(49)32(47)30(23(27)3)40(43,5)6)28(46)19-29-42(34,21-54-29)57-24(4)45/h8-18,27-29,31-34,36,46-48,53H,19-21H2,1-7H3,(H,44,50)/b22-8+/t27-,28-,29+,31-,32+,33+,34-,36-,41+,42-,43+/m0/s1
Standard InChI (Main Layer) InChI=1S/C43H51NO13/c1-8-22(2)37(50)44-31(25-15-11-9-12-16-25)33(48)39(52)55-27-20-43(53)36(56-38(51)26-17-13-10-14-18-26)34-41(7,35(49)32(47)30(23(27)3)40(43,5)6)28(46)19-29-42(34,21-54-29)57-24(4)45/h8-18,27-29,31-34,36,46-48,53H,19-21H2,1-7H3,(H,44,50)

Cluster

Phytochemical cluster No. 49
KCF-S cluster No. 238

Link

ChEMBL

By standard InChI CHEMBL311251
By standard InChI Main Layer CHEMBL311251 CHEMBL398922 CHEMBL503720 CHEMBL1473701

KEGG

By LinkDB

CTD

By CAS RN

Human Protein / Gene in interaction

24 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein CHEMBL1473701 CHEMBL2114784 (1)
1 / 1
O75496 Geminin Unclassified protein CHEMBL1473701 CHEMBL2114843 (1) CHEMBL2114780 (1)
0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein CHEMBL1473701 CHEMBL1613838 (1)
0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL1473701 CHEMBL2114810 (1)
7 / 3
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL1473701 CHEMBL1794401 (1)
0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein CHEMBL1473701 CHEMBL1614342 (1)
1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL1473701 CHEMBL1738588 (1)
0 / 0
O00167 Eyes absent homolog 2 Enzyme CHEMBL1473701 CHEMBL1614315 (1)
0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL1473701 CHEMBL2354311 (1)
1 / 0
Q13748 Tubulin alpha-3C/D chain Structural CHEMBL311251 CHEMBL728403 (1)
0 / 0
P68366 Tubulin alpha-4A chain Structural CHEMBL311251 CHEMBL728403 (1)
0 / 0
Q9H4B7 Tubulin beta-1 chain Structural CHEMBL311251 CHEMBL728403 (1)
1 / 0
P04350 Tubulin beta-4A chain Structural CHEMBL311251 CHEMBL728403 (1)
2 / 0
Q3ZCM7 Tubulin beta-8 chain Structural CHEMBL311251 CHEMBL728403 (1)
0 / 0
P07437 Tubulin beta chain Structural CHEMBL311251 CHEMBL728403 (1)
0 / 0
Q71U36 Tubulin alpha-1A chain Structural CHEMBL311251 CHEMBL728403 (1)
1 / 1
P68371 Tubulin beta-4B chain Structural CHEMBL311251 CHEMBL728403 (1)
0 / 0
Q13509 Tubulin beta-3 chain Structural CHEMBL311251 CHEMBL728403 (1)
2 / 1
P68363 Tubulin alpha-1B chain Unclassified protein CHEMBL311251 CHEMBL728403 (1)
0 / 0
Q13885 Tubulin beta-2A chain Structural CHEMBL311251 CHEMBL728403 (1)
0 / 0
Q6PEY2 Tubulin alpha-3E chain Unclassified protein CHEMBL311251 CHEMBL728403 (1)
0 / 0
Q9BQE3 Tubulin alpha-1C chain Unclassified protein CHEMBL311251 CHEMBL728403 (1)
0 / 0
Q9BUF5 Tubulin beta-6 chain Structural CHEMBL311251 CHEMBL728403 (1)
0 / 0
Q9BVA1 Tubulin beta-2B chain Structural CHEMBL311251 CHEMBL728403 (1)
1 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (17)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#614039 Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 Q13509
#128101 Dystonia 4, torsion, autosomal dominant; dyt4 P04350
#600638 Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a Q13509
#137800 Glioma susceptibility 1; glm1 O75874
#612438 Leukodystrophy, hypomyelinating, 6; hld6 P04350
#611603 Lissencephaly 3; lis3 Q71U36
#613112 Macrothrombocytopenia, autosomal dominant, tubb1-related Q9H4B7
#174800 Mccune-albright syndrome; mas P63092
#257220 Niemann-pick disease, type c1; npc1 O15118
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#610031 Polymicrogyria, symmetric or asymmetric; pmgysa Q9BVA1
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (7)

KEGG disease name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00838 Congenital fibrosis of the extraocular muscles (CFEOM) Q13509 (related)
H00268 Lissencephaly (LIS) Q71U36 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)