PCIDB

Taxus yunnanensis

Index

Plant Species

Metabolite list (62)

Human Protein
/ Gene in interactions

Related Diseases

Species

KNApSAcK Entry

Organism name	Taxus yunnanensis
Genus	Taxus
Family	Taxaceae
Kingdom	Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Taxus wallichiana var. wallichiana
Linked NCBI taxonomy ID	147275
Linked level	varietas

Family

Family in NCBI taxonomy	Taxaceae
ID	25623

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Spermatophyta
ID	58024

Metabolite list (62)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster
C00036219	Taxinine	CHEMBL309787				No. 137
C00045827	Dantaxusin B / (-)-Dantaxusin B					No. 137
C00045826	Dantaxusin A / (+)-Dantaxusin A					No. 137
C00045290	Dantaxusin D / (+)-Dantaxusin D					No. 137
C00041187	Taxuspine B	CHEMBL339942				No. 137
C00041166	Taxinine E					No. 137
C00036218	Taxezopidine H	CHEMBL430558				No. 137
C00036223	Taxuspine D	CHEMBL129793				No. 137
C00036003	2-Deacetoxytaxinine J					No. 137
C00036220	Taxinine B	CHEMBL308259				No. 137
C00041148	Taxayuntin E	CHEMBL506577				No. 164	No. 49
C00041147	Taxayuntin A					No. 164	No. 49
C00036790	Baccatin III / (-)-Baccatin III	CHEMBL288043 CHEMBL1354786 CHEMBL1590876 CHEMBL2005552	C073950	10 / 17 / 16		No. 164	No. 49
C00035995	10-Deacetylbaccatin III	CHEMBL335975 CHEMBL393912 CHEMBL1565880 CHEMBL1713307 CHEMBL1976896		6 / 4 / 1		No. 164	No. 49
C00041149	Taxayuntin F					No. 164	No. 49
C00049530	Taxayuntin B					No. 164	No. 49
C00040776	19-Hydroxybaccatin III	CHEMBL447792 CHEMBL503859	C031495			No. 164	No. 49
C00041221	Yunnanxol	CHEMBL103020				No. 238	No. 49
C00035996	10-Deacetylcephalomannine	CHEMBL311251 CHEMBL398922 CHEMBL503720 CHEMBL1473701		24 / 17 / 7		No. 238	No. 49
C00036021	Epitaxol / 7-epi-Taxol	CHEMBL48 CHEMBL428647 CHEMBL418410 CHEMBL44384 CHEMBL70362 CHEMBL304291 CHEMBL317544 CHEMBL325387 CHEMBL137050 CHEMBL341418 CHEMBL352705 CHEMBL372351 CHEMBL503883 CHEMBL533732 CHEMBL601767 CHEMBL1368986 CHEMBL1394061 CHEMBL1394818 CHEMBL1429740 CHEMBL1436401		156 / 113 / 100		No. 238	No. 49
C00040850	7-Xylosyltaxol C / (+)-7-Xylosyltaxol C	CHEMBL1596636 CHEMBL1996425		10 / 11 / 10		No. 238	No. 49
C00040848	7-Xylosyltaxol					No. 238	No. 49
C00036019	7-(beta-xylosyl)taxol C					No. 238	No. 49
C00040847	7-epi-10-Deacetylcephalomannine	CHEMBL311251 CHEMBL398922 CHEMBL503720 CHEMBL1473701		24 / 17 / 7		No. 238	No. 49
C00002365	Taxol / Paclitaxel / (-)-Paclitaxel	CHEMBL48 CHEMBL428647 CHEMBL418410 CHEMBL44384 CHEMBL70362 CHEMBL304291 CHEMBL317544 CHEMBL325387 CHEMBL137050 CHEMBL341418 CHEMBL352705 CHEMBL372351 CHEMBL503883 CHEMBL533732 CHEMBL601767 CHEMBL1368986 CHEMBL1394061 CHEMBL1394818 CHEMBL1429740 CHEMBL1436401	D017239	156 / 113 / 100	487 / 231	No. 238	No. 49
C00040759	10-Deacetyltaxol-7-xyloside / (-)-10-Deacetyltaxol-7-xyloside	CHEMBL1597821		11 / 4 / 3		No. 238	No. 49
C00038119	10-Deacetyltaxol / 10-Deacetyltaxol A	CHEMBL305016 CHEMBL303257 CHEMBL302324 CHEMBL307331 CHEMBL103121 CHEMBL339540 CHEMBL368328 CHEMBL370141 CHEMBL500852 CHEMBL1314931 CHEMBL1555236 CHEMBL1560237 CHEMBL1966254 CHEMBL2111849	C031494	27 / 25 / 11		No. 238	No. 49
C00038121	Ormosin VI / 7-epi-10-Deacetyltaxol / 10-Deacetyl-7-epi-taxol	CHEMBL305016 CHEMBL303257 CHEMBL302324 CHEMBL307331 CHEMBL103121 CHEMBL339540 CHEMBL368328 CHEMBL370141 CHEMBL500852 CHEMBL1314931 CHEMBL1555236 CHEMBL1560237 CHEMBL1966254 CHEMBL2111849		27 / 25 / 11		No. 238	No. 49
C00002323	Taxol B / Cephalomannine	CHEMBL305522 CHEMBL137681 CHEMBL400128 CHEMBL1314572 CHEMBL1397662 CHEMBL1473676	C056348	28 / 15 / 11		No. 238	No. 49
C00044343	Taxayuntin H / (-)-Taxayuntin H	CHEMBL128207				No. 248
C00041203	Taxuspine V					No. 248
C00044344	Taxayuntin J / (-)-Taxayuntin J					No. 248
C00046950	Taxuyunnanine O / (-)-Taxuyunnanine O					No. 248
C00000604	(-)-Secoisolariciresinol	CHEMBL368347	C060283	2 / 1 / 1	1 / 0	No. 282	No. 21
C00036224	Taxuspine F	CHEMBL310157 CHEMBL465478				No. 297
C00036244	Yunnanxane	CHEMBL323283 CHEMBL245750	C076298	1 / 1 / 0		No. 297
C00046012	Hongdoushan C / (+)-Hongdoushan C	CHEMBL464659				No. 297
C00035997	14beta-Hydroxytaxusin					No. 297
C00046011	Hongdoushan B / (+)-Hongdoushan B	CHEMBL465655				No. 297
C00046010	Hongdoushan A / (+)-Hongdoushan A	CHEMBL465484				No. 297
C00000901	Sinenxan A / Taxuyunnanin C / Taxuyunnanine C	CHEMBL436993		1 / 1 / 0		No. 297
C00036221	Taxusin	CHEMBL368741	C107336	3 / 2 / 0		No. 297
C00040757	10-Deacetylbaccatin VI					No. 307
C00040855	9-Deacetylbaccatin VI					No. 307
C00038159	Taxayuntin / 13-Decinnamoyl-taxchinin B	CHEMBL340846				No. 307
C00007209	alpha-Conidendrin / (-)-alpha-Conidendrin	CHEMBL463246	C421915	2 / 1 / 1		No. 406
C00049440	Decinnamoyltaxinine B 11,12-epoxide					No. 481
C00036002	2'beta-Deacetoxyaustrospicatine	CHEMBL337967 CHEMBL445031				No. 538
C00033416	Taxuspine X					No. 554
C00046948	Taxuyunnanine M / (-)-Taxuyunnanine M	CHEMBL517797				No. 752
C00040786	1-Hydroxy-2,7,9-trideacetylbaccatin I / (-)-1-Hydroxy-2,7,9-trideacetylbaccatin I					No. 752
C00046949	Taxuyunnanine N / (-)-Taxuyunnanine N					No. 752
C00037891	Taxuyunnanine P					No. 752
C00037892	Taxuyunnanine Q					No. 752
C00041163	Taxine B					No. 919	No. 49
C00045289	Dantaxusin C					No. 1263
C00036222	Taxuspinanane K	CHEMBL430628				No. 1557
C00033405	Taxin B / (-)-Taxin B					No. 2136
C00046946	Taxuyunnanine K / (-)-Taxuyunnanine K					No. 2604
C00046947	Taxuyunnanine L / (-)-Taxuyunnanine L					No. 2604
C00037893	Taxuyunnanine R					No. 2604
C00041188	Taxuspine C	CHEMBL329225 CHEMBL453986				No. 2860

Human Protein / Gene in interactions

170 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00002323 C00002365 C00035995 C00035996 C00036021 C00036790 C00038119 C00038121 C00040759 C00040847 C00040850	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002323 C00002365 C00035995 C00035996 C00036021 C00038119 C00038121 C00040759 C00040847 C00040850	1 / 0
Q99700	Ataxin-2	Unclassified protein	C00002323 C00002365 C00035996 C00036021 C00036790 C00038119 C00038121 C00040759 C00040847 C00040850	1 / 1
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040759 C00040847 C00040850	1 / 1
Q9BVA1	Tubulin beta-2B chain	Structural	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	1 / 0
P68363	Tubulin alpha-1B chain	Unclassified protein	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	0 / 0
Q13509	Tubulin beta-3 chain	Structural	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	2 / 1
Q6PEY2	Tubulin alpha-3E chain	Unclassified protein	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	0 / 0
P68371	Tubulin beta-4B chain	Structural	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	0 / 0
Q71U36	Tubulin alpha-1A chain	Structural	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	1 / 1
P07437	Tubulin beta chain	Structural	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	0 / 0
Q3ZCM7	Tubulin beta-8 chain	Structural	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	0 / 0
P04350	Tubulin beta-4A chain	Structural	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	2 / 0
P68366	Tubulin alpha-4A chain	Structural	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	0 / 0
Q13748	Tubulin alpha-3C/D chain	Structural	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	0 / 0
Q13885	Tubulin beta-2A chain	Structural	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	0 / 0
Q9BUF5	Tubulin beta-6 chain	Structural	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	0 / 0
Q9H4B7	Tubulin beta-1 chain	Structural	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	1 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00035995 C00036221 C00036790 C00038119 C00038121 C00040759 C00040850	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	0 / 0
Q9BQE3	Tubulin alpha-1C chain	Unclassified protein	C00002323 C00002365 C00035996 C00036021 C00038119 C00038121 C00040847	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00002323 C00002365 C00035995 C00036021 C00036221 C00038119 C00038121	2 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00002323 C00002365 C00035996 C00036021 C00040847	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002365 C00036021 C00036221 C00038119 C00038121	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00035996 C00038119 C00038121 C00040847 C00040850	7 / 3
P08183	Multidrug resistance protein 1	drug	C00000901 C00002365 C00036021 C00036244	1 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002323 C00002365 C00036021 C00040850	1 / 2
Q9UNA4	DNA polymerase iota	Enzyme	C00002323 C00002365 C00036021 C00040759	0 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00035995 C00036790 C00040759 C00040850	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000604 C00002365 C00007209 C00036021	0 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000604 C00002365 C00007209 C00036021	1 / 0
P02545	Prelamin-A/C	Unclassified protein	C00002365 C00036021 C00036790	11 / 10
O00255	Menin	Unclassified protein	C00002323 C00002365 C00036021	2 / 5
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002323 C00002365 C00036021	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002365 C00036021 C00036790	3 / 3
P28482	Mitogen-activated protein kinase 1	Erk	C00002365 C00036021 C00036790	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002365 C00036021 C00040759	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00002365 C00036021	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00002365 C00036021	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00002365 C00036021	0 / 0
P04183	Thymidine kinase, cytosolic	Enzyme	C00002365 C00036021	0 / 1
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00002365 C00036021	0 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00002365 C00036021	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00002365 C00036021	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00002365 C00036021	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002365 C00036021	0 / 1
P05106	Integrin beta-3	Membrane receptor	C00002365 C00036021	2 / 2
P06756	Integrin alpha-V	Membrane receptor	C00002365 C00036021	0 / 0
P54132	Bloom syndrome protein	Enzyme	C00002365 C00036021	1 / 2
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00002365 C00036021	1 / 8
P11473	Vitamin D3 receptor	NR1I1	C00002365 C00036021	2 / 3
P14416	D(2) dopamine receptor	Dopamine receptor	C00002365 C00036021	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00002365 C00036021	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00002365 C00036021	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00002365 C00036021	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00002365 C00036021	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00002365 C00036021	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00002365 C00036021	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00002365 C00036021	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00002365 C00036021	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00002365 C00036021	1 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002365 C00036021	1 / 1
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00002365 C00036021	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00002365 C00036021	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00038119 C00038121	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00002365 C00036021	3 / 1
P37840	Alpha-synuclein	Unclassified protein	C00002365 C00036021	4 / 2
P00918	Carbonic anhydrase 2	Lyase	C00002365 C00036021	1 / 2
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00002365 C00036021	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00002365 C00036021	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00002365 C00036021	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00002365 C00036021	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00002365 C00036021	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00002365 C00036021	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00002365 C00036021	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00002365 C00036021	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00002365 C00036021	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00002365 C00036021	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00002365 C00036021	1 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00002365 C00036021	0 / 0
P08311	Cathepsin G	S1A	C00002365 C00036021	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00002365 C00036021	1 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00002365 C00036021	0 / 0
P03956	Interstitial collagenase	M10A	C00002365 C00036021	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00002365 C00036021	0 / 0
O15245	Solute carrier family 22 member 1	Drug uniporter	C00002365 C00036021	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00035995 C00040759	1 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00002323 C00040850	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00002365 C00036021	1 / 0
P14780	Matrix metalloproteinase-9	M10A	C00002365 C00036021	2 / 2
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00002365 C00036021	0 / 0
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00002365 C00036021	1 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00002365 C00036021	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00002365 C00036021	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00002365 C00036021	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00002365 C00036021	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00002365 C00036021	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00002365 C00036021	2 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00002365 C00036021	5 / 3
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00002365 C00036021	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00002365 C00036021	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00002365 C00036021	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00002365 C00036021	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00002365 C00036021	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00002365 C00036021	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00002365 C00036021	1 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00002365 C00036021	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00002365 C00036021	2 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002365 C00036021	0 / 0
P25021	Histamine H2 receptor	Histamine receptor	C00002365 C00036021	0 / 0
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00002365 C00036021	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00002365 C00036021	0 / 0
Q01453	Peripheral myelin protein 22	Unclassified protein	C00002365 C00036021	5 / 2
P17252	Protein kinase C alpha type	Alpha	C00002365 C00036021	0 / 0
P21439	Multidrug resistance protein 3	Enzyme	C00002365 C00036021	3 / 2
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00002365 C00036021	0 / 0
P03372	Estrogen receptor	NR3A1	C00002365 C00036021	1 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00002365 C00036021	1 / 0
P22303	Acetylcholinesterase	Hydrolase	C00002365 C00036021	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00002365 C00036021	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00002365 C00036021	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00002365 C00036021	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00002365 C00036021	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00002365 C00036021	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00002365 C00036021	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00002365 C00036021	0 / 0
P29466	Caspase-1	C14	C00002365 C00036021	0 / 0
P04062	Glucosylceramidase	Enzyme	C00038119 C00038121	6 / 4
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00002365 C00036021	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00002365 C00036021	0 / 0
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00002365 C00036021	1 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002365 C00036021	4 / 3
Q16539	Mitogen-activated protein kinase 14	p38	C00002365 C00036021	0 / 0
P10275	Androgen receptor	NR3C4	C00002365 C00036021	3 / 4
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00002365 C00036021	1 / 0
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00002365 C00036021	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00002365 C00036021	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00002365 C00036021	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00002365 C00036021	1 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00002365 C00036021	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00002365 C00036021	0 / 0
Q07817	Bcl-2-like protein 1	Other cytosolic protein	C00002365 C00036021	0 / 0
P10415	Apoptosis regulator Bcl-2	Other cytosolic protein	C00002365 C00036021	0 / 7
P33527	Multidrug resistance-associated protein 1	drugs	C00002365 C00036021	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00002365 C00036021	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00002365 C00036021	1 / 1
O00167	Eyes absent homolog 2	Enzyme	C00035996 C00040847	0 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00002365 C00036021	1 / 1
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002365 C00036021	1 / 1
P10632	Cytochrome P450 2C8	Cytochrome P450 2C8	C00002365 C00036021	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00002365 C00036021	7 / 37
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00002365 C00036021	0 / 1
Q5T3U5	Multidrug resistance-associated protein 7	Unclassified protein	C00002365 C00036021	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00002365 C00036021	0 / 0
P08246	Neutrophil elastase	S1A	C00002365 C00036021	2 / 1
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00002365 C00036021	2 / 2
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00002365 C00036021	0 / 3
P21728	D(1A) dopamine receptor	Dopamine receptor	C00002365 C00036021	0 / 0
O95342	Bile salt export pump	drug	C00002365 C00036021	2 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00002365 C00036021	2 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00002365 C00036021	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00002365 C00036021	4 / 1
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00002365 C00036021	1 / 1
P01215	Glycoprotein hormones alpha chain	Unclassified protein	C00040850	0 / 3
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00040759	0 / 0
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00040759	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00036790	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00036790	2 / 2
P00352	Retinal dehydrogenase 1	Enzyme	C00036790	0 / 0

487 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00000604 C00002365
5552	SRGN, PPG, PRG, PRG1	serglycin	C00002365
10347	ABCA7, ABCA-SSN, ABCX	ATP-binding cassette, sub-family A (ABC1), member 7	C00002365
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00002365
8647	ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP	ATP-binding cassette, sub-family B (MDR/TAP), member 11	C00002365
5244	ABCB4, ABC21, GBD1, ICP3, MDR2, MDR2/3, MDR3, PFIC-3, PGY3	ATP-binding cassette, sub-family B (MDR/TAP), member 4 (EC:3.6.3.44)	C00002365
10058	ABCB6, ABC, ABC14, DUH3, LAN, MCOPCB7, MTABC3, PRP, umat	ATP-binding cassette, sub-family B (MDR/TAP), member 6	C00002365
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00002365
89845	ABCC10, EST182763, MRP7, SIMRP7	ATP-binding cassette, sub-family C (CFTR/MRP), member 10	C00002365
1244	ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	C00002365
8714	ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	C00002365
10057	ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	C00002365
9429	ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1	ATP-binding cassette, sub-family G (WHITE), member 2	C00002365
33	ACADL, ACAD4, LCAD	acyl-CoA dehydrogenase, long chain (EC:1.3.8.8)	C00002365
57007	ACKR3, CMKOR1, CXC-R7, CXCR-7, CXCR7, GPR159, RDC-1, RDC1	atypical chemokine receptor 3	C00002365
112	ADCY6, AC6	adenylate cyclase 6 (EC:4.6.1.1)	C00002365
120	ADD3, ADDL	adducin 3 (gamma)	C00002365
159	ADSS, ADEH, ADSS_2	adenylosuccinate synthase (EC:6.3.4.4)	C00002365
9131	AIFM1, AIF, CMTX4, COWCK, COXPD6, PDCD8	apoptosis-inducing factor, mitochondrion-associated, 1	C00002365
231	AKR1B1, ADR, ALDR1, ALR2, AR	aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21)	C00002365
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00002365
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00002365
208	AKT2, HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA	v-akt murine thymoma viral oncogene homolog 2 (EC:2.7.11.1)	C00002365
10000	AKT3, MPPH, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2	v-akt murine thymoma viral oncogene homolog 3 (EC:2.7.11.1)	C00002365
223	ALDH9A1, ALDH4, ALDH7, ALDH9, E3, TMABADH	aldehyde dehydrogenase 9 family, member A1 (EC:1.2.1.3 1.2.1.19 1.2.1.47)	C00002365
79053	ALG8, CDG1H	ALG8, alpha-1,3-glucosyltransferase (EC:2.4.1.265)	C00002365
267	AMFR, GP78, RNF45	autocrine motility factor receptor, E3 ubiquitin protein ligase (EC:6.3.2.19)	C00002365
8125	ANP32A, C15orf1, HPPCn, I1PP2A, LANP, MAPM, PHAP1, PHAPI, PP32	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	C00002365
301	ANXA1, ANX1, LPC1	annexin A1	C00002365
307	ANXA4, ANX4, PIG28, ZAP36	annexin A4	C00002365
653145	ANXA8, ANX8	annexin A8	C00002365
316	AOX1, AO, AOH1	aldehyde oxidase 1 (EC:1.2.3.1)	C00002365
317	APAF1, APAF-1, CED4	apoptotic peptidase activating factor 1	C00002365
378708	APITD1, CENP-S, CENPS, FAAP16, MHF1	apoptosis-inducing, TAF9-like domain 1	C00002365
334	APLP2, APLP-2, APPH, APPL2, CDEBP	amyloid beta (A4) precursor-like protein 2	C00002365
27350	APOBEC3C, A3C, APOBEC1L, ARDC2, ARDC4, ARP5, PBI, bK150C2.3	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C	C00002365
347	APOD	apolipoprotein D	C00002365
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00002365
374	AREG, AR, CRDGF, SDGF	amphiregulin	C00002365
377	ARF3	ADP-ribosylation factor 3	C00002365
396	ARHGDIA, GDIA1, NPHS8, RHOGDI, RHOGDI-1	Rho GDP dissociation inhibitor (GDI) alpha	C00002365
407	ARR3, ARRX	arrestin 3, retinal (X-arrestin)	C00002365
259266	ASPM, ASP, Calmbp1, MCPH5	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	C00002365
22809	ATF5, ATFX, HMFN0395	activating transcription factor 5	C00002365
523	ATP6V1A, ATP6A1, ATP6V1A1, HO68, VA68, VPP2, Vma1	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A (EC:3.6.3.14)	C00002365
538	ATP7A, DSMAX, MK, MNK, SMAX3	ATPase, Cu++ transporting, alpha polypeptide (EC:3.6.3.54)	C00002365
6790	AURKA, AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7	aurora kinase A (EC:2.7.11.1)	C00002365
558	AXL, JTK11, UFO	AXL receptor tyrosine kinase (EC:2.7.10.1)	C00002365
572	BAD, BBC2, BCL2L8	BCL2-associated agonist of cell death	C00002365
397543			C00002365
578	BAK1, BAK, BAK-LIKE, BCL2L7, CDN1	BCL2-antagonist/killer 1	C00002365
581	BAX, BCL2L4	BCL2-associated X protein	C00002365
27113	BBC3, JFY-1, JFY1, PUMA	BCL2 binding component 3	C00002365
585	BBS4	Bardet-Biedl syndrome 4	C00002365
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00002365
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00002365
8678	BECN1, ATG6, VPS30, beclin1	beclin 1, autophagy related	C00002365
633	BGN, DSPG1, PG-S1, PGI, SLRR1A	biglycan	C00002365
637	BID, FP497	BH3 interacting domain death agonist	C00002365
274	BIN1, AMPH2, AMPHL, SH3P9	bridging integrator 1	C00002365
55909	BIN3	bridging integrator 3	C00002365
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00002365
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00002365
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00002365
655	BMP7, OP-1	bone morphogenetic protein 7	C00002365
672	BRCA1, BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PPP1R53, PSCP, RNF53	breast cancer 1, early onset	C00002365
10950	BTG3, ANA, TOB5, TOB55, TOFA	BTG family, member 3	C00002365
701	BUB1B, BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1	BUB1 mitotic checkpoint serine/threonine kinase B (EC:2.7.11.1)	C00002365
9184	BUB3, BUB3L, hBUB3	BUB3 mitotic checkpoint protein	C00002365
57035	C1orf63, DJ465N24.2.1, NPD014, RP3-465N24.4	chromosome 1 open reading frame 63	C00002365
771	CA12, CAXII, HsT18816	carbonic anhydrase XII (EC:4.2.1.1)	C00002365
816	CAMK2B, CAM2, CAMK2, CAMKB	calcium/calmodulin-dependent protein kinase II beta (EC:2.7.11.17)	C00002365
4076	CAPRIN1, GPIAP1, GPIP137, M11S1, RNG105, p137GPI	cell cycle associated protein 1	C00002365
843	CASP10, ALPS2, FLICE2, MCH4	caspase 10, apoptosis-related cysteine peptidase (EC:3.4.22.63)	C00002365
100506742	CASP12, CASP-12, CASP12P1	caspase 12 (gene/pseudogene)	C00002365
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00002365
837	CASP4, ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX	caspase 4, apoptosis-related cysteine peptidase (EC:3.4.22.57)	C00002365
838	CASP5, ICE(rel)III, ICEREL-III, ICH-3	caspase 5, apoptosis-related cysteine peptidase (EC:3.4.22.58)	C00002365
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00002365
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00002365
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00002365
847	CAT	catalase (EC:1.11.1.6)	C00002365
857	CAV1, BSCL3, CGL3, MSTP085, PPH3, VIP21, CAV	caveolin 1, caveolae protein, 22kDa	C00002365
55749	CCAR1, RP11-437A18.1	cell division cycle and apoptosis regulator 1	C00002365
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00002365
891	CCNB1, CCNB	cyclin B1	C00002365
9133	CCNB2, HsT17299	cyclin B2	C00002365
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00002365
9134	CCNE2, CYCE2	cyclin E2	C00002365
902	CCNH, CAK, p34, p37	cyclin H	C00002365
100133941	CD24, CD24A	CD24 molecule	C00002365
29126	CD274, B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1	CD274 molecule	C00002365
959	CD40LG, CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L	CD40 ligand	C00002365
4179	CD46, AHUS2, MCP, MIC10, TLX, TRA2.10	CD46 molecule, complement regulatory protein	C00002365
961	CD47, IAP, MER6, OA3	CD47 molecule	C00002365
978	CDA, CDD	cytidine deaminase (EC:3.5.4.5)	C00002365
8555	CDC14B, CDC14B3, Cdc14B1, Cdc14B2, hCDC14B	cell division cycle 14B (EC:3.1.3.16 3.1.3.48)	C00002365
991	CDC20, CDC20A, bA276H19.3, p55CDC	cell division cycle 20	C00002365
995	CDC25C, CDC25, PPP1R60	cell division cycle 25C (EC:3.1.3.48)	C00002365
996	CDC27, ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, HNUC, NUC2	cell division cycle 27	C00002365
988	CDC5L, CDC5, CDC5-LIKE, CEF1, PCDC5RP, dJ319D22.1	cell division cycle 5-like	C00002365
79577	CDC73, C1orf28, HPTJT, HRPT2, HYX	cell division cycle 73	C00002365
83879	CDCA7, JPO1	cell division cycle associated 7	C00002365
1009	CDH11, CAD11, CDHOB, OB, OSF-4	cadherin 11, type 2, OB-cadherin (osteoblast)	C00002365
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00002365
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00002365
23552	CDK20, CCRK, CDCH, P42, PNQALRE	cyclin-dependent kinase 20 (EC:2.7.11.22)	C00002365
1022	CDK7, CAK1, CDKN7, HCAK, MO15, STK1, p39MO15	cyclin-dependent kinase 7 (EC:2.7.11.23 2.7.11.22)	C00002365
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00002365
1031	CDKN2C, INK4C, p18, p18-INK4C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	C00002365
1063	CENPF, CENF, PRO1779, hcp-1	centromere protein F, 350/400kDa	C00002365
8837	CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS	CASP8 and FADD-like apoptosis regulator	C00002365
55743	CHFR, RNF116, RNF196	checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase	C00002365
1365	CLDN3, C7orf1, CPE-R2, CPETR2, HRVP1, RVP1	claudin 3	C00002365
6320	CLEC11A, CLECSF3, LSLCL, P47, SCGF	C-type lectin domain family 11, member A	C00002365
10845	CLPX	caseinolytic mitochondrial matrix peptidase chaperone subunit	C00002365
1191	CLU, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2	clusterin	C00002365
80781	COL18A1, KNO, KNO1, KS	collagen, type XVIII, alpha 1	C00002365
1277	COL1A1, OI4	collagen, type I, alpha 1	C00002365
1278	COL1A2, OI4	collagen, type I, alpha 2	C00002365
1282	COL4A1, HANAC, ICH, POREN1, arresten	collagen, type IV, alpha 1	C00002365
1284	COL4A2, ICH, POREN2	collagen, type IV, alpha 2	C00002365
1291	COL6A1, OPLL	collagen, type VI, alpha 1	C00002365
1292	COL6A2, PP3610	collagen, type VI, alpha 2	C00002365
1293	COL6A3	collagen, type VI, alpha 3	C00002365
1294	COL7A1, EBD1, EBDCT, EBR1	collagen, type VII, alpha 1	C00002365
11316	COPE, epsilon-COP	coatomer protein complex, subunit epsilon	C00002365
1355	COX15, CEMCOX2	cytochrome c oxidase assembly homolog 15 (yeast)	C00002365
10063	COX17	COX17 cytochrome c oxidase copper chaperone	C00002365
8804	CREG1, CREG	cellular repressor of E1A-stimulated genes 1	C00002365
1440	CSF3, C17orf33, CSF3OS, GCSF, G-CSF	colony stimulating factor 3 (granulocyte)	C00002365
10664	CTCF, MRD21	CCCTC-binding factor (zinc finger protein)	C00002365
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00002365
1501	CTNND2, GT24, NPRAP	catenin (cadherin-associated protein), delta 2	C00002365
1514	CTSL, CATL, CTSL1, MEP	cathepsin L (EC:3.4.22.15)	C00002365
2017	CTTN, EMS1	cortactin	C00002365
6374	CXCL5, ENA-78, SCYB5	chemokine (C-X-C motif) ligand 5	C00002365
7852	CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM	chemokine (C-X-C motif) receptor 4	C00002365
10663	CXCR6, BONZO, CD186, STRL33, TYMSTR	chemokine (C-X-C motif) receptor 6	C00002365
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00002365
1588	CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM	cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00002365
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00002365
1558	CYP2C8, CPC8, CYPIIC8, MP-12/MP-20	cytochrome P450, family 2, subfamily C, polypeptide 8 (EC:1.14.14.1)	C00002365
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00002365
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00002365
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00002365
3491	CYR61, CCN1, GIG1, IGFBP10	cysteine-rich, angiogenic inducer, 61	C00002365
1635	DCTD	dCMP deaminase (EC:3.5.4.12)	C00002365
9416	DDX23, PRPF28, SNRNP100, U5-100K, U5-100KD, prp28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 (EC:3.6.4.13)	C00002365
9191	DEDD, CASP8IP1, DEDD1, DEFT, FLDED1	death effector domain containing	C00002365
1676	DFFA, DFF-45, DFF1, ICAD	DNA fragmentation factor, 45kDa, alpha polypeptide	C00002365
1718	DHCR24, DCE, Nbla03646, SELADIN1, seladin-1	24-dehydrocholesterol reductase (EC:1.3.1.72)	C00002365
56616	DIABLO, DFNA64, SMAC	diablo, IAP-binding mitochondrial protein	C00002365
9988	DMTF1, DMP1, DMTF, hDMP1	cyclin D binding myb-like transcription factor 1	C00002365
1806	DPYD, DHP, DHPDHASE, DPD	dihydropyrimidine dehydrogenase (EC:1.3.1.2)	C00002365
1832	DSP, DP, DPI, DPII	desmoplakin	C00002365
1845	DUSP3, VHR	dual specificity phosphatase 3 (EC:3.1.3.16 3.1.3.48)	C00002365
1869	E2F1, E2F-1, RBAP1, RBBP3, RBP3	E2F transcription factor 1	C00002365
1871	E2F3, E2F-3	E2F transcription factor 3	C00002365
1875	E2F5, E2F-5	E2F transcription factor 5, p130-binding	C00002365
1938	EEF2, EEF-2, EF-2, EF2, SCA26	eukaryotic translation elongation factor 2	C00002365
84455	EFCAB7, RP4-534K7.1	EF-hand calcium binding domain 7	C00002365
1942	EFNA1, B61, ECKLG, EFL1, EPLG1, LERK-1, LERK1, TNFAIP4	ephrin-A1	C00002365
1950	EGF, HOMG4, URG	epidermal growth factor	C00002365
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00002365
26298	EHF, ESE3, ESE3B, ESEJ	ets homologous factor	C00002365
9451	EIF2AK3, PEK, PERK, WRS	eukaryotic translation initiation factor 2-alpha kinase 3 (EC:2.7.11.1)	C00002365
1973	EIF4A1, DDX2A, EIF-4A, EIF4A, eIF-4A-I, eIF4A-I	eukaryotic translation initiation factor 4A1 (EC:3.6.4.13)	C00002365
1984	EIF5A, EIF-5A, EIF5A1, eIF5AI	eukaryotic translation initiation factor 5A	C00002365
79767	ELMO3, CED-12, CED12, ELMO-3	engulfment and cell motility 3	C00002365
2014	EMP3, YMP	epithelial membrane protein 3	C00002365
5168	ENPP2, ATX, ATX-X, AUTOTAXIN, LysoPLD, NPP2, PD-IALPHA, PDNP2	ectonucleotide pyrophosphatase/phosphodiesterase 2 (EC:3.1.4.39)	C00002365
4072	EPCAM, DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1	epithelial cell adhesion molecule	C00002365
2056	EPO, EP, MVCD2	erythropoietin	C00002365
2064	ERBB2, CD340, HER-2, HER-2/neu, HER2, MLN_19, NEU, NGL, TKR1	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1)	C00002365
2065	ERBB3, ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (EC:2.7.10.1)	C00002365
2066	ERBB4, ALS19, HER4, p180erbB4	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 (EC:2.7.10.1)	C00002365
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00002365
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00002365
2147	F2, PT, RPRGL2, THPH1	coagulation factor II (thrombin) (EC:3.4.21.5)	C00002365
2152	F3, CD142, TF, TFA	coagulation factor III (thromboplastin, tissue factor)	C00002365
8772	FADD, MORT1	Fas (TNFRSF6)-associated via death domain	C00002365
10447	FAM3C, ILEI	family with sequence similarity 3, member C	C00002365
55120	FANCL, FAAP43, PHF9, POG	Fanconi anemia, complementation group L	C00002365
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00002365
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00002365
2200	FBN1, ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2	fibrillin 1	C00002365
2222	FDFT1, DGPT, ERG9, SQS, SS	farnesyl-diphosphate farnesyltransferase 1 (EC:2.5.1.21)	C00002365
2224	FDPS, FPPS, FPS	farnesyl diphosphate synthase (EC:2.5.1.1 2.5.1.10)	C00002365
2247	FGF2, BFGF, FGF-2, FGFB, HBGF-2	fibroblast growth factor 2 (basic)	C00002365
2250	FGF5, HBGF-5, Smag-82	fibroblast growth factor 5	C00002365
2273	FHL1, FHL-1, FHL1A, FHL1B, FLH1A, KYOT, SLIM, SLIM-1, SLIM1, SLIMMER, XMPMA	four and a half LIM domains 1	C00002365
6624	FSCN1, FAN1, HSN, SNL, p55	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)	C00002365
2495	FTH1, FHC, FTH, FTHL6, PIG15, PLIF	ferritin, heavy polypeptide 1 (EC:1.16.3.1)	C00002365
2512	FTL, NBIA3	ferritin, light polypeptide	C00002365
5045	FURIN, FUR, PACE, PCSK3, SPC1	furin (paired basic amino acid cleaving enzyme) (EC:3.4.21.75)	C00002365
5349	FXYD3, MAT8, PLML	FXYD domain containing ion transport regulator 3	C00002365
1647	GADD45A, DDIT1, GADD45	growth arrest and DNA-damage-inducible, alpha	C00002365
51809	GALNT7, GALNAC-T7, GalNAcT7	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7) (EC:2.4.1.41)	C00002365
2593	GAMT, CCDS2, PIG2, TP53I2	guanidinoacetate N-methyltransferase (EC:2.1.1.2)	C00002365
2644	GCHFR, GFRP, HsT16933, P35	GTP cyclohydrolase I feedback regulator	C00002365
2670	GFAP	glial fibrillary acidic protein	C00002365
2673	GFPT1, CMSTA1, GFA, GFAT, GFAT_1, GFAT1, GFAT1m, GFPT, GFPT1L, MSLG	glutamine--fructose-6-phosphate transaminase 1 (EC:2.6.1.16)	C00002365
2674	GFRA1, GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1	GDNF family receptor alpha 1	C00002365
2821	GPI, AMF, GNPI, NLK, PGI, PHI, SA-36, SA36	glucose-6-phosphate isomerase (EC:5.3.1.9)	C00002365
2859	GPR35	G protein-coupled receptor 35	C00002365
2934	GSN, ADF, AGEL	gelsolin	C00002365
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00002365
2949	GSTM5, GSTM5-5, GTM5	glutathione S-transferase mu 5 (EC:2.5.1.18)	C00002365
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00002365
2952	GSTT1	glutathione S-transferase theta 1 (EC:2.5.1.18)	C00002365
2969	GTF2I, BAP135, BTKAP1, DIWS, GTFII-I, IB291, SPIN, TFII-I, WBS, WBSCR6	general transcription factor IIi	C00002365
51512	GTSE1, B99	G-2 and S-phase expressed 1	C00002365
2990	GUSB, BG, MPS7	glucuronidase, beta (EC:3.2.1.31)	C00002365
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00002365
9734	HDAC9, HD7, HD7b, HD9, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, MITR	histone deacetylase 9 (EC:3.5.1.98)	C00002365
30289			C00002365
3146	HMGB1, HMG1, HMG3, SBP-1	high mobility group box 1	C00002365
9324	HMGN3, PNAS-25, TRIP7	high mobility group nucleosomal binding domain 3	C00002365
3161	HMMR, CD168, IHABP, RHAMM	hyaluronan-mediated motility receptor (RHAMM)	C00002365
3181	HNRNPA2B1, HNRNPA2, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, IBMPFD2, RNPA2, SNRPB1	heterogeneous nuclear ribonucleoprotein A2/B1	C00002365
3182	HNRNPAB, ABBP1, HNRPAB	heterogeneous nuclear ribonucleoprotein A/B	C00002365
3187	HNRNPH1, HNRPH, HNRPH1, hnRNPH	heterogeneous nuclear ribonucleoprotein H1 (H)	C00002365
51361	HOOK1, HK1	hook microtubule-tethering protein 1	C00002365
3295	HSD17B4, DBP, MFE-2, MPF-2, PRLTS1, SDR8C1	hydroxysteroid (17-beta) dehydrogenase 4 (EC:4.2.1.107 4.2.1.119 1.1.1.n12)	C00002365
3311	HSPA7, HSP70B	heat shock 70kDa protein 7 (HSP70B)	C00002365
8988	HSPB3, DHMN2C, HMN2C, HSPL27	heat shock 27kDa protein 3	C00002365
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00002365
3418	IDH2, D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH	isocitrate dehydrogenase 2 (NADP+), mitochondrial (EC:1.1.1.42)	C00002365
10437	IFI30, GILT, IFI-30, IP30	interferon, gamma-inducible protein 30	C00002365
3487	IGFBP4, BP-4, HT29-IGFBP, IBP4, IGFBP-4	insulin-like growth factor binding protein 4	C00002365
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00002365
3598	IL13RA2, CD213A2, CT19, IL-13R, IL13BP	interleukin 13 receptor, alpha 2	C00002365
55540	IL17RB, CRL4, EVI27, IL17BR, IL17RH1	interleukin 17 receptor B	C00002365
3554	IL1R1, CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80	interleukin 1 receptor, type I	C00002365
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00002365
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00002365
3638	INSIG1, CL-6, CL6	insulin induced gene 1	C00002365
9636	ISG15, G1P2, IFI15, IP17, UCRP, hUCRP	ISG15 ubiquitin-like modifier	C00002365
3683	ITGAL, CD11A, LFA-1, LFA1A	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	C00002365
9270	ITGB1BP1, ICAP-1A, ICAP-1B, ICAP-1alpha, ICAP1, ICAP1A, ICAP1B	integrin beta 1 binding protein 1	C00002365
3693	ITGB5	integrin, beta 5	C00002365
3694	ITGB6	integrin, beta 6	C00002365
9445	ITM2B, ABRI, BRI, BRI2, BRICD2B, E25B, E3-16, FBD, imBRI2	integral membrane protein 2B	C00002365
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00002365
3777	KCNK3, K2p3.1, OAT1, PPH4, TASK, TASK-1, TBAK1	potassium channel, subfamily K, member 3	C00002365
3778	KCNMA1, BKTM, KCa1.1, MaxiK, SAKCA, SLO, SLO-ALPHA, SLO1, bA205K10.1, mSLO1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	C00002365
23030	KDM4B, JMJD2B, TDRD14B	lysine (K)-specific demethylase 4B	C00002365
9817	KEAP1, INrf2, KLHL19	kelch-like ECH-associated protein 1	C00002365
57613		KIAA1467	C00002365
11127	KIF3A, FLA10, KLP-20	kinesin family member 3A	C00002365
354	KLK3, APS, KLK2A1, PSA, hK3	kallikrein-related peptidase 3 (EC:3.4.21.77)	C00002365
3860	KRT13, CK13, K13	keratin 13	C00002365
3855	KRT7, CK7, K2C7, K7, SCL	keratin 7	C00002365
3920	LAMP2, CD107b, LAMP-2, LAMPB, LGP110	lysosomal-associated membrane protein 2	C00002365
3937	LCP2, SLP-76, SLP76	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	C00002365
3949	LDLR, FH, FHC, LDLCQ2	low density lipoprotein receptor	C00002365
3960	LGALS4, GAL4, L36LBP	lectin, galactoside-binding, soluble, 4	C00002365
3978	LIG1	ligase I, DNA, ATP-dependent (EC:6.5.1.1)	C00002365
9516	LITAF, PIG7, SIMPLE, TP53I7	lipopolysaccharide-induced TNF factor	C00002365
4053	LTBP2, C14orf141, GLC3D, LTBP3, MSPKA, MSTP031, WMS3	latent transforming growth factor beta binding protein 2	C00002365
4085	MAD2L1, HSMAD2, MAD2	MAD2 mitotic arrest deficient-like 1 (yeast)	C00002365
8567	MADD, DENN, IG20, RAB3GEP	MAP-kinase activating death domain	C00002365
81631	MAP1LC3B, ATG8F, LC3B, MAP1A/1BLC3, MAP1LC3B-a	microtubule-associated protein 1 light chain 3 beta	C00002365
5604	MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1	mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)	C00002365
6416	MAP2K4, JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1, SKK1	mitogen-activated protein kinase kinase 4 (EC:2.7.12.2)	C00002365
4214	MAP3K1, MAPKKK1, MEKK, MEKK_1, MEKK1, SRXY6	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase (EC:2.7.11.25)	C00002365
4217	MAP3K5, ASK1, MAPKKK5, MEKK5	mitogen-activated protein kinase kinase kinase 5 (EC:2.7.11.25)	C00002365
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00002365
5603	MAPK13, MAPK_13, MAPK-13, PRKM13, SAPK4, p38delta	mitogen-activated protein kinase 13 (EC:2.7.11.24)	C00002365
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00002365
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00002365
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00002365
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00002365
8550	MAPKAPK5, MAPKAP-K5, MK-5, MK5, PRAK	mitogen-activated protein kinase-activated protein kinase 5 (EC:2.7.11.1)	C00002365
22919	MAPRE1, EB1	microtubule-associated protein, RP/EB family, member 1	C00002365
22924	MAPRE3, EB3, EBF3, EBF3-S, RP3	microtubule-associated protein, RP/EB family, member 3	C00002365
4137	MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU	microtubule-associated protein tau	C00002365
4170	MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT	myeloid cell leukemia sequence 1 (BCL2-related)	C00002365
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00002365
5469	MED1, CRSP1, CRSP200, DRIP205, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2	mediator complex subunit 1	C00002365
23389	MED13L, PROSIT240, THRAP2, TRAP240L	mediator complex subunit 13-like	C00002365
29079	MED4, ARC36, DRIP36, HSPC126, TRAP36, VDRIP	mediator complex subunit 4	C00002365
9833	MELK, HPK38	maternal embryonic leucine zipper kinase (EC:2.7.11.1 2.7.10.2)	C00002365
79006	METRN, C16orf23, c380A1.2	meteorin, glial cell differentiation regulator	C00002365
4277	MICB, PERB11.2	MHC class I polypeptide-related sequence B	C00002365
9761	MLEC, KIAA0152	malectin	C00002365
4312	MMP1, CLG, CLGN	matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7)	C00002365
4325	MMP16, C8orf57, MMP-X2, MT-MMP2, MT-MMP3, MT3-MMP	matrix metallopeptidase 16 (membrane-inserted) (EC:3.4.24.-)	C00002365
4326	MMP17, MT4-MMP	matrix metallopeptidase 17 (membrane-inserted) (EC:3.4.24.-)	C00002365
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00002365
5891	MOK, RAGE, RAGE-1, RAGE1	MOK protein kinase (EC:2.7.11.22)	C00002365
10200	MPHOSPH6, MPP, MPP-6, MPP6	M-phase phosphoprotein 6	C00002365
4356	MPP3, DLG3	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	C00002365
10205	MPZL2, EVA, EVA1	myelin protein zero-like 2	C00002365
78988	MRP63, bMRP63	mitochondrial ribosomal protein 63	C00002365
64976	MRPL40, MRP-L22, MRPL22, NLVCF, URIM	mitochondrial ribosomal protein L40	C00002365
64960	MRPS15, MPR-S15, RPMS15, S15mt	mitochondrial ribosomal protein S15	C00002365
28973	MRPS18B, C6orf14, HSPC183, HumanS18a, MRP-S18-2, MRPS18-2, PTD017, S18amt	mitochondrial ribosomal protein S18B	C00002365
6307	MSMO1, DESP4, ERG25, SC4MOL	methylsterol monooxygenase 1 (EC:1.14.13.72)	C00002365
4493	MT1E, MT1, MTD	metallothionein 1E	C00002365
4502	MT2A, MT2	metallothionein 2A	C00002365
94025	MUC16, CA125	mucin 16, cell surface associated	C00002365
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00002365
4644	MYO5A, GS1, MYH12, MYO5, MYR12	myosin VA (heavy chain 12, myoxin)	C00002365
9	NAT1, AAC1, MNAT, NAT-1, NATI	N-acetyltransferase 1 (arylamine N-acetyltransferase) (EC:2.3.1.5)	C00002365
89795	NAV3, POMFIL1, STEERIN3, unc53H3	neuron navigator 3	C00002365
64151	NCAPG, CAPG, CHCG, NY-MEL-3	non-SMC condensin I complex, subunit G	C00002365
8202	NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP	nuclear receptor coactivator 3 (EC:2.3.1.48)	C00002365
4694	NDUFA1, CI-MWFE, MWFE, ZNF183	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa (EC:1.6.99.3)	C00002365
51079	NDUFA13, B16.6, CDA016, GRIM-19, GRIM19	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13	C00002365
4696	NDUFA3, B9, CI-B9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa	C00002365
4708	NDUFB2, AGGG, CI-AGGG	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa (EC:1.6.5.3 1.6.99.3)	C00002365
4713	NDUFB7, B18, CI-B18	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa (EC:1.6.5.3 1.6.99.3)	C00002365
4728	NDUFS8, CI-23k, CI23KD, TYKY	NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) (EC:1.6.5.3 1.6.99.3)	C00002365
4723	NDUFV1, CI-51K, CI51KD, UQOR1	NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa (EC:1.6.5.3 1.6.99.3)	C00002365
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00002365
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00002365
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00002365
79570	NKAIN1, FAM77C	Na+/K+ transporting ATPase interacting 1	C00002365
4833	NME4, NDPK-D, NM23H4, nm23-H4	NME/NM23 nucleoside diphosphate kinase 4 (EC:2.7.4.6)	C00002365
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00002365
8829	NRP1, BDCA4, CD304, NP1, NRP, VEGF165R	neuropilin 1	C00002365
55270	NUDT15, MTH2, RP11-90M2.1	nudix (nucleoside diphosphate linked moiety X)-type motif 15 (EC:3.6.1.55)	C00002365
11163	NUDT4, DIPP2, DIPP2alpha, DIPP2beta	nudix (nucleoside diphosphate linked moiety X)-type motif 4 (EC:3.6.1.52)	C00002365
51203	NUSAP1, ANKT, BM037, LNP, NUSAP, PRO0310p1, Q0310, SAPL	nucleolar and spindle associated protein 1	C00002365
4968	OGG1, HMMH, HOGG1, MUTM, OGH1	8-oxoguanine DNA glycosylase (EC:4.2.99.18)	C00002365
56944	OLFML3, HNOEL-iso, OLF44	olfactomedin-like 3	C00002365
114884	OSBPL10, ORP10, OSBP9	oxysterol binding protein-like 10	C00002365
9180	OSMR, OSMRB, PLCA1	oncostatin M receptor	C00002365
11240	PADI2, PAD-H19, PAD2, PDI2	peptidyl arginine deiminase, type II (EC:3.5.3.15)	C00002365
3355109			C00002365
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00002365
5095	PCCA	propionyl CoA carboxylase, alpha polypeptide (EC:6.4.1.3)	C00002365
5111	PCNA	proliferating cell nuclear antigen	C00002365
5118	PCOLCE, PCPE, PCPE-1, PCPE1	procollagen C-endopeptidase enhancer	C00002365
5163	PDK1	pyruvate dehydrogenase kinase, isozyme 1 (EC:2.7.11.2)	C00002365
5170	PDPK1, PDK1, PDPK2, PRO0461	3-phosphoinositide dependent protein kinase-1 (EC:2.7.11.1)	C00002365
64065	PERP, KCP1, KRTCAP1, PIGPC1, RP3-496H19.1, THW, dJ496H19.1	PERP, TP53 apoptosis effector	C00002365
5286	PIK3C2A, CPK, PI3-K-C2(ALPHA), PI3-K-C2A	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha (EC:2.7.1.154)	C00002365
5311	PKD2, APKD2, PC2, PKD4, Pc-2, TRPP2	polycystic kidney disease 2 (autosomal dominant)	C00002365
5315	PKM, CTHBP, OIP3, PK3, PKM2, TCB, THBP1	pyruvate kinase, muscle (EC:2.7.1.40)	C00002365
5318	PKP2, ARVD9	plakophilin 2	C00002365
51196	PLCE1, NPHS3, PLCE, PPLC	phospholipase C, epsilon 1 (EC:3.1.4.11)	C00002365
5347	PLK1, PLK, STPK13	polo-like kinase 1 (EC:2.7.11.21)	C00002365
10733	PLK4, SAK, STK18	polo-like kinase 4 (EC:2.7.11.21)	C00002365
5376	PMP22, CMT1A, CMT1E, DSS, GAS-3, HMSNIA, HNPP, Sp110	peripheral myelin protein 22	C00002365
51426	POLK, DINB1, DINP, POLQ	polymerase (DNA directed) kappa (EC:2.7.7.7)	C00002365
22932	POMZP3, POM-ZP3, POM121	POM121 and ZP3 fusion	C00002365
5447	POR, CPR, CYPOR, P450R	P450 (cytochrome) oxidoreductase (EC:1.6.2.4)	C00002365
10631	POSTN, OSF-2, OSF2, PDLPOSTN, PN, periostin	periostin, osteoblast specific factor	C00002365
8611	PPAP2A, LLP1a, LPP1, PAP-2a, PAP2	phosphatidic acid phosphatase type 2A (EC:3.1.3.4)	C00002365
8612	PPAP2C, LPP2, PAP-2c, PAP2-g	phosphatidic acid phosphatase type 2C (EC:3.1.3.4)	C00002365
5479	PPIB, CYP-S1, CYPB, OI9, SCYLP	peptidylprolyl isomerase B (cyclophilin B) (EC:5.2.1.8)	C00002365
5500	PPP1CB, PP-1B, PP1B, PP1beta, PPP1CD	protein phosphatase 1, catalytic subunit, beta isozyme (EC:3.1.3.16 3.1.3.53)	C00002365
55607	PPP1R9A, NRB1, NRBI, Neurabin-I	protein phosphatase 1, regulatory subunit 9A	C00002365
9055	PRC1, ASE1	protein regulator of cytokinesis 1	C00002365
11108	PRDM4, PFM1	PR domain containing 4	C00002365
7001	PRDX2, NKEF-B, NKEFB, PRP, PRX2, PRXII, PTX1, TDPX1, TPX1, TSA	peroxiredoxin 2 (EC:1.11.1.15)	C00002365
8842	PROM1, AC133, CD133, CORD12, MCDR2, PROML1, RP41, STGD4	prominin 1	C00002365
79056	PRRG4, PRGP4, TMG4	proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)	C00002365
38175			C00002365
5660	PSAP, GLBA, SAP1	prosaposin	C00002365
5685	PSMA4, HC9, HsT17706, PSC9	proteasome (prosome, macropain) subunit, alpha type, 4 (EC:3.4.25.1)	C00002365
5689	PSMB1, HC5, PMSB1, PSC5	proteasome (prosome, macropain) subunit, beta type, 1 (EC:3.4.25.1)	C00002365
5694	PSMB6, DELTA, LMPY, Y	proteasome (prosome, macropain) subunit, beta type, 6 (EC:3.4.25.1)	C00002365
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00002365
10728	PTGES3, P23, TEBP, cPGES	prostaglandin E synthase 3 (cytosolic) (EC:5.3.99.3)	C00002365
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002365
5753	PTK6, BRK	protein tyrosine kinase 6 (EC:2.7.10.2)	C00002365
5783	PTPN13, FAP-1, PNP1, PTP-BAS, PTP-BL, PTP1E, PTPL1, PTPLE, hPTP1E	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) (EC:3.1.3.48)	C00002365
5778	PTPN7, BPTP-4, HEPTP, LC-PTP, LPTP, PTPNI	protein tyrosine phosphatase, non-receptor type 7 (EC:3.1.3.48)	C00002365
54870	QRICH1	glutamine-rich 1	C00002365
5768	QSOX1, Q6, QSCN6	quiescin Q6 sulfhydryl oxidase 1 (EC:1.8.3.2)	C00002365
5879	RAC1, Rac-1, TC-25, p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	C00002365
5894	RAF1, CRAF, NS5, Raf-1, c-Raf	v-raf-1 murine leukemia viral oncogene homolog 1 (EC:2.7.11.1)	C00002365
10267	RAMP1	receptor (G protein-coupled) activity modifying protein 1	C00002365
9771	RAPGEF5, GFR, MR-GEF, REPAC	Rap guanine nucleotide exchange factor (GEF) 5	C00002365
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00002365
10741	RBBP9, BOG, RBBP10	retinoblastoma binding protein 9	C00002365
5947	RBP1, CRABP-I, CRBP, CRBP1, CRBPI, RBPC	retinol binding protein 1, cellular	C00002365
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00002365
5985	RFC5, RFC36	replication factor C (activator 1) 5, 36.5kDa	C00002365
5993	RFX5	regulatory factor X, 5 (influences HLA class II expression)	C00002365
8625	RFXANK, ANKRA1, BLS, F14150_1, RFX-B	regulatory factor X-associated ankyrin-containing protein	C00002365
89941	RHOT2, ARHT2, C16orf39, MIRO-2, MIRO2, RASL	ras homolog family member T2 (EC:3.6.5.-)	C00002365
6093	ROCK1, P160ROCK, ROCK-I	Rho-associated, coiled-coil containing protein kinase 1 (EC:2.7.11.1)	C00002365
6134	RPL10, AUTSX5, DXS648, DXS648E, L10, NOV, QM	ribosomal protein L10	C00002365
6147	RPL23A, L23A, MDA20	ribosomal protein L23a	C00002365
6176	RPLP1, LP1, P1, RPP1	ribosomal protein, large, P1	C00002365
393715			C00002365
6241	RRM2, R2, RR2, RR2M	ribonucleotide reductase M2 (EC:1.17.4.1)	C00002365
50484	RRM2B, MTDPS8A, MTDPS8B, P53R2	ribonucleotide reductase M2 B (TP53 inducible) (EC:1.17.4.1)	C00002365
6247	RS1, RS, XLRS1	retinoschisin 1	C00002365
6242	RTKN	rhotekin	C00002365
10856	RUVBL2, ECP51, INO80J, REPTIN, RVB2, TIH2, TIP48, TIP49B	RuvB-like AAA ATPase 2 (EC:3.6.4.12)	C00002365
6275	S100A4, 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98	S100 calcium binding protein A4	C00002365
6286	S100P, MIG9	S100 calcium binding protein P	C00002365
6447	SCG5, 7B2, P7B2, SGNE1, SgV	secretogranin V (7B2 protein)	C00002365
57758	SCUBE2, CEGB1, CEGF1, CEGP1	signal peptide, CUB domain, EGF-like 2	C00002365
6383	SDC2, CD362, HSPG, HSPG1, SYND2	syndecan 2	C00002365
5055	SERPINB2, HsT1201, PAI, PAI-2, PAI2, PLANH2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	C00002365
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00002365
5176	SERPINF1, EPC-1, OI12, OI6, PEDF	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	C00002365
6443	SGCB, A3b, LGMD2E, SGC	sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)	C00002365
6452	SH3BP2, 3BP-2, 3BP2, CRBM, CRPM	SH3-domain binding protein 2	C00002365
23411	SIRT1, SIR2L1	sirtuin 1	C00002365
6502	SKP2, FBL1, FBXL1, FLB1, p45	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase	C00002365
6558	SLC12A2, BSC, BSC2, NKCC1	solute carrier family 12 (sodium/potassium/chloride transporter), member 2	C00002365
5002	SLC22A18, BWR1A, BWSCR1A, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5, p45-BWR1A	solute carrier family 22, member 18	C00002365
6581	SLC22A3, EMT, EMTH, OCT3	solute carrier family 22 (organic cation transporter), member 3	C00002365
10864	SLC22A7, NLT, OAT2	solute carrier family 22 (organic anion transporter), member 7	C00002365
291	SLC25A4, 1, AAC1, ANT, ANT_1, ANT1, MTDPS12, PEO2, PEO3, T1	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	C00002365
1317	SLC31A1, COPT1, CTR1	solute carrier family 31 (copper transporter), member 1	C00002365
6548	SLC9A1, APNH, NHE-1, NHE1	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	C00002365
6617	SNAPC1, PTFgamma, SNAP43	small nuclear RNA activating complex, polypeptide 1, 43kDa	C00002365
79622	SNRNP25, C16orf33	small nuclear ribonucleoprotein 25kDa (U11/U12)	C00002365
6627	SNRPA1, Lea1	small nuclear ribonucleoprotein polypeptide A'	C00002365
29887	SNX10, OPTB8	sorting nexin 10	C00002365
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00002365
11262	SP140, LYSP100, LYSP100-A, LYSP100-B	SP140 nuclear body protein	C00002365
6678	SPARC, ON	secreted protein, acidic, cysteine-rich (osteonectin)	C00002365
10653	SPINT2, DIAR3, HAI-2, HAI2, Kop, PB	serine peptidase inhibitor, Kunitz type, 2	C00002365
23461	ABCA5, ABC13, EST90625	ATP-binding cassette, sub-family A (ABC1), member 5	C00002365
6717	SRI, CP-22, CP22, SCN, V19	sorcin	C00002365
6734	SRPR, DP, Sralpha	signal recognition particle receptor (docking protein)	C00002365
6774	STAT3, APRF, HIES	signal transducer and activator of transcription 3 (acute-phase response factor)	C00002365
6781	STC1, STC	stanniocalcin 1	C00002365
10963	STIP1, HOP, IEF-SSP-3521, P60, STI1, STI1L	stress-induced-phosphoprotein 1	C00002365
3925	STMN1, C1orf215, LAP18, Lag, OP18, PP17, PP19, PR22, SMN	stathmin 1	C00002365
10923	SUB1, P15, PC4, p14	SUB1 homolog (S. cerevisiae)	C00002365
8803	SUCLA2, A-BETA, MTDPS5, SCS-betaA	succinate-CoA ligase, ADP-forming, beta subunit (EC:6.2.1.5)	C00002365
10460	TACC3, ERIC-1, ERIC1	transforming, acidic coiled-coil containing protein 3	C00002365
6890	TAP1, ABC17, ABCB2, APT1, D6S114E, PSF-1, PSF1, RING4, TAP1*0102N, TAP1N	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	C00002365
6996	TDG, hTDG	thymine-DNA glycosylase (EC:3.2.2.29)	C00002365
7015	TERT, CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT	telomerase reverse transcriptase (EC:2.7.7.49)	C00002365
7020	TFAP2A, AP-2, AP-2alpha, AP2TF, BOFS, TFAP2	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	C00002365
7022	TFAP2C, AP2-GAMMA, ERF1, TFAP2G, hAP-2g	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	C00002365
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00002365
7980	TFPI2, PP5, REF1, TFPI-2	tissue factor pathway inhibitor 2	C00002365
55258	THNSL2, SOFAT, THS2, TSH2	threonine synthase-like 2 (S. cerevisiae) (EC:4.2.3.-)	C00002365
7070	THY1, CD90	Thy-1 cell surface antigen	C00002365
7072	TIA1, TIA-1, WDM	TIA1 cytotoxic granule-associated RNA binding protein	C00002365
26517	TIMM13, TIM13, TIM13B, TIMM13A, TIMM13B, ppv1	translocase of inner mitochondrial membrane 13 homolog (yeast)	C00002365
29928	TIMM22, TEX4, TIM22	translocase of inner mitochondrial membrane 22 homolog (yeast)	C00002365
27134	TJP3, ZO-3, ZO3	tight junction protein 3	C00002365
80194	TMEM134	transmembrane protein 134	C00002365
65084	TMEM135, PMP52	transmembrane protein 135	C00002365
64418	TMEM168	transmembrane protein 168	C00002365
79161	TMEM243, C7orf23, MM-TRAG	transmembrane protein 243, mitochondrial	C00002365
9528	TMEM59, C1orf8, HSPC001	transmembrane protein 59	C00002365
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002365
7128	TNFAIP3, A20, OTUD7C, TNFA1P2	tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12)	C00002365
8797	TNFRSF10A, APO2, CD261, DR4, TRAILR-1, TRAILR1	tumor necrosis factor receptor superfamily, member 10a	C00002365
8795	TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9	tumor necrosis factor receptor superfamily, member 10b	C00002365
8743	TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL	tumor necrosis factor (ligand) superfamily, member 10	C00002365
8741	TNFSF13, APRIL, CD256, TALL-2, TALL2, TRDL-1, ZTNF2	tumor necrosis factor (ligand) superfamily, member 13	C00002365
10673	TNFSF13B, BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, ZTNF4	tumor necrosis factor (ligand) superfamily, member 13b	C00002365
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00002365
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00002365
7163	TPD52, D52, N8L, PC-1, PrLZ, hD52	tumor protein D52	C00002365
7185	TRAF1, EBI6, MGC:10353	TNF receptor-associated factor 1	C00002365
7188	TRAF5, MGC:39780, RNF84	TNF receptor-associated factor 5	C00002365
23321	TRIM2, CMT2R, RNF86	tripartite motif containing 2	C00002365
11078	TRIOBP, DFNB28, TARA, dJ37E16.4	TRIO and F-actin binding protein	C00002365
7222	TRPC3, TRP3	transient receptor potential cation channel, subfamily C, member 3	C00002365
203068	TUBB, M40, OK/SW-cl.56, TUBB1, TUBB5	tubulin, beta class I	C00002365
1890	TYMP, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF	thymidine phosphorylase (EC:2.4.2.4)	C00002365
7298	TYMS, HST422, TMS, TS	thymidylate synthetase (EC:2.1.1.45)	C00002365
9246	UBE2L6, RIG-B, UBCH8	ubiquitin-conjugating enzyme E2L 6 (EC:6.3.2.19)	C00002365
7372	UMPS, OPRT	uridine monophosphate synthetase (EC:2.4.2.10 4.1.1.23)	C00002365
7374	UNG, DGU, HIGM4, HIGM5, UDG, UNG1, UNG15, UNG2	uracil-DNA glycosylase (EC:3.2.2.27)	C00002365
7389	UROD, PCT, UPD	uroporphyrinogen decarboxylase (EC:4.1.1.37)	C00002365
8078	USP5, ISOT	ubiquitin specific peptidase 5 (isopeptidase T) (EC:3.4.19.12)	C00002365
8673	VAMP8, EDB, VAMP-8	vesicle-associated membrane protein 8	C00002365
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00002365
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00002365
80349	WDR61, REC14, SKI8	WD repeat domain 61	C00002365
11197	WIF1, WIF-1	WNT inhibitory factor 1	C00002365
49856	WRAP73, WDR8	WD repeat containing, antisense to TP73	C00002365
55884	WSB2, SBA2	WD repeat and SOCS box containing 2	C00002365
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00002365
7514	XPO1, CRM1, emb, exp1	exportin 1 (CRM1 homolog, yeast)	C00002365
10971	YWHAQ, 14-3-3, 1C5, HS1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	C00002365
678	ZFP36L2, BRF2, ERF-2, ERF2, RNF162C, TIS11D	ZFP36 ring finger protein-like 2	C00002365
79818	ZNF552	zinc finger protein 552	C00002365
9406	ZRANB2, ZIS, ZIS1, ZIS2, ZNF265	zinc finger, RAN-binding domain containing 2	C00002365

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (128)

OMIM	preferred title	UniProt
#300438	17-beta-hydroxysteroid dehydrogenase x deficiency	Q99714
#100100	Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism	P20309
#219080	Acth-independent macronodular adrenal hyperplasia; aimah	P63092
#202300	Adrenocortical carcinoma, hereditary; adcc	P04637
#103780	Alcohol dependence	P08172 P14416 P31645
#614373	Amyotrophic lateral sclerosis 16, juvenile; als16	Q99720
#300068	Androgen insensitivity syndrome; ais	P10275
#312300	Androgen insensitivity, partial; pais	P10275
#608584	Asthma-related traits, susceptibility to, 2	Q6W5P4
#614740	Basal cell carcinoma, susceptibility to, 7; bcc7	P04637
#187800	Bleeding disorder, platelet-type, 16; bdplt16	P05106
#210900	Bloom syndrome; blm	P54132
#602025	Body mass index quantitative trait locus 9; bmiq9	P41968
%606641	Body mass index; bmi	P37231
#300615	Brunner syndrome	P21397
#115200	Cardiomyopathy, dilated, 1a; cmd1a	P02545
#212112	Cardiomyopathy, dilated, with hypergonadotropic hypogonadism	P02545
#609338	Carotid intimal medial thickness 1	P37231
#118300	Charcot-marie-tooth disease and deafness	Q01453
#605588	Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1	P02545
#118220	Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a	Q01453
#605479	Cholestasis, benign recurrent intrahepatic, 2; bric2	O95342
#614972	Cholestasis, intrahepatic, of pregnancy 3; icp3	P21439
#601847	Cholestasis, progressive familial intrahepatic, 2; pfic2	O95342
#602347	Cholestasis, progressive familial intrahepatic, 3; pfic3	P21439
#114500	Colorectal cancer; crc	P84022
#614039	Cortical dysplasia, complex, with other brain malformations 1; cdcbm1	Q13509
#162800	Cyclic neutropenia	P08246
#127750	Dementia, lewy body; dlb	P37840
#612522	Diabetes mellitus, insulin-dependent, 22; iddm22	P51681
#119900	Digital clubbing, isolated congenital	P15428
#609535	Drug metabolism, poor, cyp2c19-related	P33261
#608902	Drug metabolism, poor, cyp2d6-related	P10635
#128101	Dystonia 4, torsion, autosomal dominant; dyt4	P04350
#181350	Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2	P02545
#133239	Esophageal cancer	P04637
#615363	Estrogen resistance; estrr	P03372
#600638	Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a	Q13509
#600274	Frontotemporal dementia; ftd	P10636
#600803	Gallbladder disease 1; gbd1	P21439
#613659	Gastric cancer	P04626
#137215	Gastric cancer, hereditary diffuse; hdgc	P04626
#608013	Gaucher disease, perinatal lethal	P04062
#230800	Gaucher disease, type i	P04062
#230900	Gaucher disease, type ii	P04062
#231000	Gaucher disease, type iii	P04062
#231005	Gaucher disease, type iiic	P04062
#231095	Ghosal hematodiaphyseal dysplasia; ghdd	P24557
#273800	Glanzmann thrombasthenia; gt	P05106
#137800	Glioma susceptibility 1; glm1	O75874 P04626 P37231
#139393	Guillain-barre syndrome, familial; gbs	Q01453
#605130	Hairy elbows, short stature, facial dysmorphism, and developmental delay	Q03164
#610140	Heart-hand syndrome, slovenian type	P02545
#609423	Human immunodeficiency virus type 1, susceptibility to	P41597 P51681
#176670	Hutchinson-gilford progeria syndrome; hgps	P02545
#237450	Hyperbilirubinemia, rotor type; hblrr	Q9NPD5 Q9Y6L6
#145000	Hyperparathyroidism 1; hrpt1	O00255
#145900	Hypertrophic neuropathy of dejerine-sottas	Q01453
#259100	Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1	P15428
#612244	Inflammatory bowel disease 13; ibd13	P08183
#603932	Intervertebral disc disease; idd	P14780
#612438	Leukodystrophy, hypomyelinating, 6; hld6	P04350
#151623	Li-fraumeni syndrome 1; lfs1	P04637
#151660	Lipodystrophy, familial partial, type 2; fpld2	P02545
#604367	Lipodystrophy, familial partial, type 3; fpld3	P37231
#611603	Lissencephaly 3; lis3	Q71U36
#613795	Loeys-dietz syndrome, type 3; lds3	P84022
#613688	Long qt syndrome 2; lqt2	Q12809
#211980	Lung cancer	P00533 P04626 P04637
#613112	Macrothrombocytopenia, autosomal dominant, tubb1-related	Q9H4B7
#608516	Major depressive disorder; mdd	P08172
#248370	Mandibuloacral dysplasia with type a lipodystrophy; mada	P02545
#174800	Mccune-albright syndrome; mas	P63092
#300705	Mental retardation, x-linked 17; mrx17	Q99714
%300852	Mental retardation, x-linked 88; mrx88	P50052
#300220	Mental retardation, x-linked, syndromic 10; mrxs10	Q99714
#613073	Metaphyseal anadysplasia 2; mandp2	P14780
#131100	Multiple endocrine neoplasia, type i; men1	O00255
#126200	Multiple sclerosis, susceptibility to; ms	P08575
#613205	Muscular dystrophy, congenital, lmna-related	P02545
#159001	Muscular dystrophy, limb-girdle, type 1b; lgmd1b	P02545
#607948	Mycobacterium tuberculosis, susceptibility to	P11473
#159900	Myoclonic dystonia	P14416
#162500	Neuropathy, hereditary, with liability to pressure palsies; hnpp	Q01453
#202700	Neutropenia, severe congenital, 1, autosomal dominant; scn1	P08246
#257220	Niemann-pick disease, type c1; npc1	O15118
#601665	Obesity	P32245 P37231
#164230	Obsessive-compulsive disorder; ocd	P31645
#604715	Orthostatic intolerance	P23975
#166350	Osseous heteroplasia, progressive; poh	P63092
#259730	Osteopetrosis, autosomal recessive 3; optb3	P00918
#167000	Ovarian cancer	P04626
#260500	Papilloma of choroid plexus; cpp	P04637
#168601	Parkinson disease 1, autosomal dominant; park1	P37840
#605543	Parkinson disease 4, autosomal dominant; park4	P37840
#168600	Parkinson disease, late-onset; pd	P04062 P37840
#260540	Parkinson-dementia syndrome	P10636
#613135	Parkinsonism-dystonia, infantile; pkdys	Q01959
#172700	Pick disease of brain	P10636
#102200	Pituitary adenoma, growth hormone-secreting	P63092
#610031	Polymicrogyria, symmetric or asymmetric; pmgysa	Q9BVA1
#103580	Pseudohypoparathyroidism, type ia; php1a	P63092
#603233	Pseudohypoparathyroidism, type ib; php1b	P63092
#612462	Pseudohypoparathyroidism, type ic; php1c	P63092
#607276	Resting heart rate, variation in	P08588
#275210	Restrictive dermopathy, lethal	P02545
#604906	Schizophrenia 9; sczd9	P49798
#181500	Schizophrenia; sczd	P49798
#608971	Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive	P08575
#609620	Short qt syndrome 1; sqt1	Q12809
#313200	Spinal and bulbar muscular atrophy, x-linked 1; smax1	P10275
#253300	Spinal muscular atrophy, type i; sma1	Q16637
#253550	Spinal muscular atrophy, type ii; sma2	Q16637
#253400	Spinal muscular atrophy, type iii; sma3	Q16637
#271150	Spinal muscular atrophy, type iv; sma4	Q16637
#183090	Spinocerebellar ataxia 2; sca2	Q99700
#607250	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1	Q9NUW8
#275355	Squamous cell carcinoma, head and neck; hnscc	P04637
#601104	Supranuclear palsy, progressive, 1; psnp1	P10636
#187950	Thrombocythemia 1; thcyt1	P40225
#188570	Thyroid hormone resistance, generalized, autosomal dominant; grth	P10828
#274300	Thyroid hormone resistance, generalized, autosomal recessive; grth	P10828
#145650	Thyroid hormone resistance, selective pituitary; prth	P10828
#190300	Tremor, hereditary essential, 1; etm1	P35462
#277440	Vitamin d-dependent rickets, type 2a; vddr2a	P11473
#610379	West nile virus, susceptibility to	P51681
#278750	Xeroderma pigmentosum, variant type; xpv	Q9Y253
#112100	Yt blood group antigen	P22303

KEGG DISEASE (112)

KEGG	name	UniProt
H00033	Adrenal carcinoma	O00255 (related) P04637 (related)
H00034	Carcinoid	O00255 (related)
H00045	Malignant islet cell carcinoma	O00255 (related)
H00246	Primary hyperparathyroidism	O00255 (related)
H01102	Pituitary adenomas	O00255 (related)
H00136	Niemann-Pick disease type C (NPC)	O15118 (related)
H00624	Familial cholestasis	O95342 (related) P21439 (related)
H00016	Oral cancer	P00533 (related) P00533 (marker) P04637 (related) P04637 (marker)
H00017	Esophageal cancer	P00533 (related) P04637 (related) P04637 (marker) P35354 (related)
H00018	Gastric cancer	P00533 (related) P04626 (related) P04637 (related) P10415 (related)
H00022	Bladder cancer	P00533 (related) P04626 (related) P04637 (related)
H00028	Choriocarcinoma	P00533 (related) P03956 (related) P04626 (related) P04637 (related) P10415 (related)
H00030	Cervical cancer	P00533 (related) P04626 (related) P10415 (related)
H00042	Glioma	P00533 (related) P00533 (marker) P04637 (related) P04637 (marker)
H00055	Laryngeal cancer	P00533 (related) P00533 (marker) P04637 (related) P04637 (marker)
H00241	Combined proximal and distal renal tubular acidosis (RTA type 3)	P00918 (related)
H00436	Osteopetrosis	P00918 (related)
H00081	Hashimoto's thyroiditis	P01215 (marker)
H00082	Graves' disease	P01215 (marker)
H00250	Congenital nongoitrous hypothyroidism (CHNG)	P01215 (marker)
H00264	Charcot-Marie-Tooth disease (CMT)	P02545 (related) Q01453 (related)
H00294	Dilated cardiomyopathy (DCM)	P02545 (related)
H00420	Familial partial lipodystrophy (FPL)	P02545 (related) P37231 (related)
H00563	Emery-Dreifuss muscular dystrophy	P02545 (related)
H00590	Congenital muscular dystrophies (CMD/MDC)	P02545 (related)
H00593	Limb-girdle muscular dystrophy (LGMD)	P02545 (related)
H00601	Hutchinson-Gilford progeria syndrome	P02545 (related)
H00663	Restrictive dermopathy	P02545 (related)
H00665	Mandibuloacral dysplasia	P02545 (related)
H01216	Left ventricular noncompaction (LVNC)	P02545 (related)
H00026	Endometrial Cancer	P03372 (marker) P04626 (related) P04637 (related) Q92731 (marker)
H00066	Lewy body dementia (LBD)	P04062 (related) P37840 (related)
H00126	Gaucher disease	P04062 (related)
H00426	Defects in the degradation of ganglioside	P04062 (related)
H00810	Progressive myoclonic epilepsy (PME)	P04062 (related)
H00599	46,XX disorders of sex development (Disorders related to androgen excess)	P04150 (related)
H00005	Chronic lymphocytic leukemia (CLL)	P04183 (marker) P04637 (related) P10415 (related)
H00019	Pancreatic cancer	P04626 (related) P04637 (related) P04637 (marker)
H00027	Ovarian cancer	P04626 (related) P04637 (related)
H00031	Breast cancer	P04626 (related) P04626 (marker) P04637 (related)
H00046	Cholangiocarcinoma	P04626 (related) P04637 (related) P35354 (related)
H00004	Chronic myeloid leukemia (CML)	P04637 (related)
H00006	Hairy-cell leukemia	P04637 (related)
H00008	Burkitt lymphoma	P04637 (related)
H00009	Adult T-cell leukemia	P04637 (related)
H00010	Multiple myeloma	P04637 (related)
H00013	Small cell lung cancer	P04637 (related) P10415 (related)
H00014	Non-small cell lung cancer	P04637 (related)
H00015	Malignant pleural mesothelioma	P04637 (related)
H00020	Colorectal cancer	P04637 (related) P04637 (marker)
H00025	Penile cancer	P04637 (related) P04637 (marker) P14780 (related) P35354 (related)
H00029	Vulvar cancer	P04637 (related)
H00032	Thyroid cancer	P04637 (related) P37231 (related)
H00036	Osteosarcoma	P04637 (related) P08684 (marker)
H00038	Malignant melanoma	P04637 (related)
H00039	Basal cell carcinoma	P04637 (related)
H00040	Squamous cell carcinoma	P04637 (related)
H00041	Kaposi's sarcoma	P04637 (related) P10415 (related)
H00044	Cancer of the anal canal	P04637 (related)
H00047	Gallbladder cancer	P04637 (related)
H00048	Hepatocellular carcinoma	P04637 (related)
H00881	Li-Fraumeni syndrome	P04637 (related)
H01007	Choroid plexus papilloma	P04637 (related)
H00021	Renal cell carcinoma	P04637 (marker)
H00083	Allograft rejection	P05106 (related)
H00226	Glanzmann thrombasthenia	P05106 (related)
H00093	Combined immunodeficiencies (CIDs)	P06239 (related)
H00079	Asthma	P07550 (related)
H00100	Neutropenic disorders	P08246 (related)
H00091	T-B+Severe combined immunodeficiencies (SCIDs)	P08575 (related)
H00024	Prostate cancer	P10275 (related)
H00062	Spinal and bulbar muscular atrophy (SBMA)	P10275 (related)
H00608	46,XY disorders of sex development (Disorders in androgen synthesis or action)	P10275 (related)
H00609	46,XY disorders of sex development (Other)	P10275 (related)
H00054	Nasopharyngeal cancer	P10415 (related)
H00058	Amyotrophic lateral sclerosis (ALS)	P10636 (related)
H00077	Progressive supranuclear palsy (PSP)	P10636 (related)
H00078	Frontotemporal lobar degeneration (FTLD)	P10636 (related)
H00249	Thyroid hormone resistance syndrome	P10828 (related)
H00342	Tuberculosis	P11473 (related)
H00784	Localized autosomal recessive hypotrichosis	P11473 (related)
H01143	Vitamin D-dependent rickets	P11473 (related)
H01205	Coumarin resistance	P11712 (related)
H00479	Metaphyseal dysplasias	P14780 (related)
H00457	Primary hypertrophic osteoarthropathy (PHO)	P15428 (related)
H01246	Isolated congenital nail clubbing (ICNC)	P15428 (related)
H00548	Brunner syndrome	P21397 (related)
H01213	Gallbladder disease	P21439 (related)
H01031	Orthostatic intolerance (OI)	P23975 (related)
H00490	Diaphyseal dysplasia with anemia (Ghosal)	P24557 (related)
H01171	Poor drug metabolism (PM)	P33261 (related)
H00409	Type II diabetes mellitus	P37231 (related)
H00057	Parkinson's disease (PD)	P37840 (related)
H00227	Congenital amegakaryocytic thrombocytopenia (CAMT)	P40225 (marker)
H00480	Non-syndromic X-linked mental retardation	P50052 (related) Q99714 (related)
H00094	DNA repair defects	P54132 (related)
H00296	Defects in RecQ helicases	P54132 (related)
H00244	Pseudohypoparathyroidism	P63092 (related)
H00441	Progressive osseous heteroplasia (POH)	P63092 (related)
H00501	Fibrous dysplasia, polyostotic	P63092 (related)
H01296	Hereditary neuropathy with liability to pressure palsies (HNPP)	Q01453 (related)
H00001	Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)	Q03164 (related) Q03164 (marker)
H00002	Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)	Q03164 (related)
H00720	Long QT syndrome	Q12809 (related)
H00725	Short QT syndrome	Q12809 (related)
H00838	Congenital fibrosis of the extraocular muscles (CFEOM)	Q13509 (related)
H00455	Spinal muscular atrophy (SMA)	Q16637 (related)
H00268	Lissencephaly (LIS)	Q71U36 (related)
H00063	Spinocerebellar ataxia (SCA)	Q99700 (related) Q9NUW8 (related)
H00658	Syndromic X-linked mental retardation	Q99714 (related)
H00925	2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency	Q99714 (related)
H00403	Disorders of nucleotide excision repair	Q9Y253 (related)

Diseases related to CTD interactions

231 disease in interactions with metabolites

MESH or OMIM	name	KNApSAcK metabolite
D015746	Abdominal Pain	C00002365
D000230	Adenocarcinoma	C00002365
C538231	Adenocarcinoma of lung	C00002365
D000380	Agranulocytosis	C00002365
C554498	AIDS-related Kaposi sarcoma	C00002365
D000435	Alcoholic Intoxication	C00002365
D000505	Alopecia	C00002365
D000707	Anaphylaxis	C00002365
D000740	Anemia	C00002365
D000755	Anemia, Sickle Cell	C00002365
D000783	Aneurysm	C00002365
D017541	Aneurysm, False	C00002365
D000855	Anorexia	C00002365
D018771	Arthralgia	C00002365
D001247	Asthenia	C00002365
D001259	Ataxia	C00002365
D050197	Atherosclerosis	C00002365
D001281	Atrial Fibrillation	C00002365
D054537	Atrioventricular Block	C00002365
D001416	Back Pain	C00002365
D001855	Bone Marrow Diseases	C00002365
D001859	Bone Neoplasms	C00002365
D001919	Bradycardia	C00002365
D001927	Brain Diseases	C00002365
D001929	Brain Edema	C00002365
D020520	Brain Infarction	C00002365
D001932	Brain Neoplasms	C00002365
D001943	Breast Neoplasms	C00002365
D001986	Bronchial Spasm	C00002365
D002037	Bundle-Branch Block	C00002365
D002277	Carcinoma	C00002365
D018270	Carcinoma, Ductal, Breast	C00002365
D018269	Carcinoma, Endometrioid	C00002365
D006528	Carcinoma, Hepatocellular	C00002365
D018287	Carcinoma, Large Cell	C00002365
D018827	Carcinoma, Lewis Lung	C00002365
D002289	Carcinoma, Non-Small-Cell Lung	C00002365
D002294	Carcinoma, Squamous Cell	C00002365
C535575	Carcinoma, squamous cell of head and neck	C00002365
D002295	Carcinoma, Transitional Cell	C00002365
D009202	Cardiomyopathies	C00002365
D002493	Central Nervous System Diseases	C00002365
D002637	Chest Pain	C00002365
D015209	Cholangitis, Sclerosing	C00002365
D002779	Cholestasis	C00002365
D015834	Cochlear Diseases	C00002365
D003072	Cognition Disorders	C00002365
D017091	Colitis, Ischemic	C00002365
D015179	Colorectal Neoplasms	C00002365
D003128	COMA	C00002365
D003221	Confusion	C00002365
D003244	Consciousness Disorders	C00002365
D003248	Constipation	C00002365
D003251	Constriction, Pathologic	C00002365
D054059	Coronary Occlusion	C00002365
D003329	Coronary Vasospasm	C00002365
D003638	Deafness	C00002365
D003711	Demyelinating Diseases	C00002365
D003866	Depressive Disorder	C00002365
D003967	Diarrhea	C00002365
D004172	Diplopia	C00002365
D004244	Dizziness	C00002365
D003875	Drug Eruptions	C00002365
D004342	Drug Hypersensitivity	C00002365
D056486	Drug-Induced Liver Injury	C00002365
D064420	Drug-Related Side Effects and Adverse Reactions	C00002365
D004408	Dysgeusia	C00002365
D004417	Dyspnea	C00002365
D053159	Dysuria	C00002365
D004487	Edema	C00002365
D016889	Endometrial Neoplasms	C00002365
D004751	Enteritis	C00002365
D044504	Enterocolitis, Neutropenic	C00002365
D004761	Enterocolitis, Pseudomembranous	C00002365
D004890	Erythema	C00002365
D004892	Erythema Multiforme	C00002365
D004938	Esophageal Neoplasms	C00002365
D004941	Esophagitis	C00002365
D005076	Exanthema	C00002365
D005119	Extravasation of Diagnostic and Therapeutic Materials	C00002365
D005155	Facial Nerve Diseases	C00002365
D005158	Facial Paralysis	C00002365
D005185	Fallopian Tube Neoplasms	C00002365
D005221	Fatigue	C00002365
D005334	Fever	C00002365
D005483	Flushing	C00002365
D005549	Foreign-Body Reaction	C00002365
D020233	Gait Disorders, Neurologic	C00002365
D005767	Gastrointestinal Diseases	C00002365
D005833	Genital Neoplasms, Female	C00002365
D005909	Glioblastoma	C00002365
D005910	Glioma	C00002365
D006212	Hallucinations	C00002365
D006261	Headache	C00002365
D006258	Head and Neck Neoplasms	C00002365
D006311	Hearing Disorders	C00002365
D006312	Hearing Loss, Bilateral	C00002365
D006319	Hearing Loss, Sensorineural	C00002365
D006323	Heart Arrest	C00002365
D006327	Heart Block	C00002365
D006331	Heart Diseases	C00002365
D006333	Heart Failure	C00002365
D006394	Hemangiosarcoma	C00002365
D006402	Hematologic Diseases	C00002365
D006501	Hepatic Encephalopathy	C00002365
D006685	Hoarseness	C00002365
D006930	Hyperalgesia	C00002365
D006932	Hyperbilirubinemia	C00002365
D006943	Hyperglycemia	C00002365
D006967	Hypersensitivity	C00002365
D006973	Hypertension	C00002365
D006976	Hypertension, Pulmonary	C00002365
D006987	Hypesthesia	C00002365
D007022	Hypotension	C00002365
D007024	Hypotension, Orthostatic	C00002365
D045823	Ileus	C00002365
D058922	Inflammatory Breast Neoplasms	C00002365
D007674	Kidney Diseases	C00002365
D007806	Language Disorders	C00002365
D007822	Laryngeal Neoplasms	C00002365
D007890	Leiomyosarcoma	C00002365
D053609	Lethargy	C00002365
D007938	Leukemia	C00002365
D007945	Leukemia, Lymphoid	C00002365
D015470	Leukemia, Myeloid, Acute	C00002365
D056784	Leukoencephalopathies	C00002365
D007970	Leukopenia	C00002365
D008080	Liposarcoma	C00002365
D008113	Liver Neoplasms	C00002365
D008114	Liver Neoplasms, Experimental	C00002365
D008171	Lung Diseases	C00002365
D017563	Lung Diseases, Interstitial	C00002365
D008175	Lung Neoplasms	C00002365
D020522	Lymphoma, Mantle-Cell	C00002365
D008228	Lymphoma, Non-Hodgkin	C00002365
D008231	Lymphopenia	C00002365
D008325	Mammary Neoplasms, Experimental	C00002365
D008545	Melanoma	C00002365
D008546	Melanoma, Experimental	C00002365
D008654	Mesothelioma	C00002365
D051346	Mobility Limitation	C00002365
D019957	Motor Skills Disorders	C00002365
D009062	Mouth Neoplasms	C00002365
D052016	Mucositis	C00002365
D009101	Multiple Myeloma	C00002365
D009120	Muscle Cramp	C00002365
D018908	Muscle Weakness	C00002365
D009135	Muscular Diseases	C00002365
D009203	Myocardial Infarction	C00002365
D017202	Myocardial Ischemia	C00002365
D009260	Nail Diseases	C00002365
D009325	Nausea	C00002365
D009336	Necrosis	C00002365
D009362	Neoplasm Metastasis	C00002365
D009364	Neoplasm Recurrence, Local	C00002365
D009369	Neoplasms	C00002365
D009374	Neoplasms, Experimental	C00002365
D009373	Neoplasms, Germ Cell and Embryonal	C00002365
D009382	Neoplasms, Unknown Primary	C00002365
D009410	Nerve Degeneration	C00002365
D009422	Nervous System Diseases	C00002365
D009437	Neuralgia	C00002365
D009443	Neuritis	C00002365
D018358	Neuroendocrine Tumors	C00002365
D009468	Neuromuscular Diseases	C00002365
D020258	Neurotoxicity Syndromes	C00002365
D009503	Neutropenia	C00002365
C537844	Nonseminomatous germ cell tumor	C00002365
D054039	Onycholysis	C00002365
D009901	Optic Nerve Diseases	C00002365
D010014	Osteolysis	C00002365
D012516	Osteosarcoma	C00002365
C538090	Ovarian epithelial cancer	C00002365
D010051	Ovarian Neoplasms	C00002365
D010146	Pain	C00002365
D010259	Paranoid Disorders	C00002365
D010292	Paresthesia	C00002365
D010300	Parkinson Disease	C00002365
D010523	Peripheral Nervous System Diseases	C00002365
D011014	Pneumonia	C00002365
D011115	Polyneuropathies	C00002365
D054038	Posterior Leukoencephalopathy Syndrome	C00002365
D054198	Precursor Cell Lymphoblastic Leukemia-Lymphoma	C00002365
D011471	Prostatic Neoplasms	C00002365
D011537	Pruritus	C00002365
D011655	Pulmonary Embolism	C00002365
D011658	Pulmonary Fibrosis	C00002365
D012008	Recurrence	C00002365
D012021	Reflex, Abnormal	C00002365
D051437	Renal Insufficiency	C00002365
D012509	Sarcoma	C00002365
D020426	Sciatic Neuropathy	C00002365
D045743	Scleroderma, Diffuse	C00002365
D012594	Scleroderma, Localized	C00002365
D012598	Sclerosis	C00002365
D012607	Scotoma	C00002365
D012640	Seizures	C00002365
D012678	Sensation Disorders	C00002365
D018805	Sepsis	C00002365
D012817	Signs and Symptoms, Digestive	C00002365
D012871	Skin Diseases	C00002365
D012878	Skin Neoplasms	C00002365
D012893	Sleep Disorders	C00002365
D055752	Small Cell Lung Carcinoma	C00002365
D012983	Soft Tissue Neoplasms	C00002365
D020886	Somatosensory Disorders	C00002365
D013118	Spinal Cord Diseases	C00002365
D013274	Stomach Neoplasms	C00002365
D013280	Stomatitis	C00002365
D013610	Tachycardia	C00002365
D013617	Tachycardia, Supraventricular	C00002365
D017180	Tachycardia, Ventricular	C00002365
D013651	Taste Disorders	C00002365
D024801	Tauopathies	C00002365
D013736	Testicular Neoplasms	C00002365
D013921	Thrombocytopenia	C00002365
D013923	Thromboembolism	C00002365
D013927	Thrombosis	C00002365
C536910	Thyroid cancer, anaplastic	C00002365
D014012	Tinnitus	C00002365
D014067	Tonsillar Neoplasms	C00002365
D001749	Urinary Bladder Neoplasms	C00002365
D014571	Urologic Neoplasms	C00002365
D002583	Uterine Cervical Neoplasms	C00002365
D014594	Uterine Neoplasms	C00002365
D018487	Ventricular Dysfunction, Left	C00002365
D018879	Ventricular Premature Complexes	C00002365
D014717	Vertigo	C00002365
D014786	Vision Disorders	C00002365
D014826	Vocal Cord Paralysis	C00002365
D014839	Vomiting	C00002365

Taxus yunnanensis

Index Plant Species Metabolite list (62) Human Protein / Gene in interactions Related Diseases

Species

KNApSAcK Entry

NCBI taxonomy

Entry

Family

Kingdom (Superkingdom)

Plant class

Metabolite list (62)

Human Protein / Gene in interactions

170 ChEMBL Protein in interactions

487 Gene in CTD interactions

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (128)

KEGG DISEASE (112)

Diseases related to CTD interactions

231 disease in interactions with metabolites

Index

Plant Species

Metabolite list (62)

Human Protein
/ Gene in interactions

Related Diseases