KNApSAcK Metabolite C00036481
Metabolite
KNApSAcK Entry
| id | C00036481 |
|---|---|
| Name | 2-Bromophenol |
| CAS RN | 95-56-7 |
| Standard InChI | InChI=1S/C6H5BrO/c7-5-3-1-2-4-6(5)8/h1-4,8H |
| Standard InChI (Main Layer) | InChI=1S/C6H5BrO/c7-5-3-1-2-4-6(5)8/h1-4,8H |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 2101 |
Link
ChEMBL
| By standard InChI | CHEMBL186007 |
|---|---|
| By standard InChI Main Layer | CHEMBL186007 |
KEGG
| By LinkDB | C14841 |
|---|
CTD
| By CAS RN | C032038 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Rhodomelaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Polysiphonia sphaerocarpa | 2804 | Rhodomelaceae | Eukaryota |
Human Protein / Gene in interaction
2 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | CHEMBL186007 |
CHEMBL833559
(1)
|
2 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | CHEMBL186007 |
CHEMBL831078
(1)
|
0 / 0 |
CTD interaction (7)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C032038 | 1583 |
CYP11A1
CYP11A CYPXIA1 P450SCC |
cytochrome P450, family 11, subfamily A, polypeptide 1 (EC:1.14.15.6) | 2-bromophenol results in increased expression of CYP11A1 mRNA |
increases expression
|
mRNA |
17447562
|
| C032038 | 1586 |
CYP17A1
CPT7 CYP17 P450C17 S17AH |
cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30) | 2-bromophenol results in increased expression of CYP17A1 mRNA |
increases expression
|
mRNA |
17447562
|
| C032038 | 1588 |
CYP19A1
ARO ARO1 CPV1 CYAR CYP19 CYPXIX P-450AROM |
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) | 2-bromophenol results in increased expression of CYP19A1 mRNA |
increases expression
|
mRNA |
17447562
|
| C032038 | 3292 |
HSD17B1
EDH17B2 EDHB17 HSD17 SDR28C1 |
hydroxysteroid (17-beta) dehydrogenase 1 (EC:1.1.1.62) | 2-bromophenol results in increased expression of HSD17B1 mRNA |
increases expression
|
mRNA |
17447562
|
| C032038 | 3295 |
HSD17B4
DBP MFE-2 MPF-2 PRLTS1 SDR8C1 |
hydroxysteroid (17-beta) dehydrogenase 4 (EC:4.2.1.107 4.2.1.119 1.1.1.n12) | 2-bromophenol results in increased expression of HSD17B4 mRNA |
increases expression
|
mRNA |
17447562
|
| C032038 | 3284 |
HSD3B2
HSD3B HSDB SDR11E2 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (EC:1.1.1.145 5.3.3.1) | 2-bromophenol results in increased expression of HSD3B2 mRNA |
increases expression
|
mRNA |
17447562
|
| C032038 | 6770 |
STAR
STARD1 |
steroidogenic acute regulatory protein | 2-bromophenol results in increased expression of STAR mRNA |
increases expression
|
mRNA |
17447562
|
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (2)
| OMIM | preferred title | UniProt |
|---|---|---|
| #114500 | Colorectal cancer; crc |
P18054
|
| #133239 | Esophageal cancer |
P18054
|