Species

KNApSAcK Entry

Organism name Polysiphonia sphaerocarpa
Genus Polysiphonia
Family Rhodomelaceae
Kingdom

NCBI taxonomy

Entry

Linked NCBI taxonomy name Polysiphonia
Linked NCBI taxonomy ID 2804
Linked level genus

Family

Family in NCBI taxonomy Rhodomelaceae
ID 2803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Eukaryota
ID 2759

Plant class

Plant class
ID

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00033540 External link 512 2,4,6-Tribromophenol
C004554
9 / 1
C00036481 External link 512 2-Bromophenol
CHEMBL186007
C032038
2 / 2 / 0 7 / 0 No. 2101
C00036569 External link 512 4-Bromophenol
CHEMBL57284
C032037
2 / 2 / 0 No. 2101
C00036465 External link 512 2,6-Dibromophenol
CHEMBL111507
C038964
5 / 7 / 2 7 / 0 No. 2101
C00033541 External link 512 2,4-Dibromophenol
CHEMBL186858
C013930
2 / 2 / 0 10 / 0 No. 2101
C00036541 External link 512 3-Bromo-4-hydroxybenzaldehyde
No. 3064
C00036515 External link 512 3,5-Dibromo-4-hydroxybenzaldehyde
CHEMBL254956
No. 3064
C00036459 External link 512 2,4,6-Tribromoanisole
No. 5831

Human Protein / Gene in interactions

5 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00033541 C00036465 C00036481 C00036569 2 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00033541 C00036465 C00036481 C00036569 0 / 0
P18507 Gamma-aminobutyric acid receptor subunit gamma-2 GABA-A gamma C00036465 4 / 2
P47870 Gamma-aminobutyric acid receptor subunit beta-2 GABA-A beta C00036465 0 / 0
P14867 Gamma-aminobutyric acid receptor subunit alpha-1 GABA-A alpha C00036465 1 / 1

12 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
6770 STAR, STARD1 steroidogenic acute regulatory protein C00033540 C00033541 C00036465 C00036481
3284 HSD3B2, HSD3B, HSDB, SDR11E2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (EC:1.1.1.145 5.3.3.1) C00033540 C00033541 C00036465 C00036481
1586 CYP17A1, CPT7, CYP17, P450C17, S17AH cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30) C00033540 C00033541 C00036465 C00036481
1583 CYP11A1, CYP11A, CYPXIA1, P450SCC cytochrome P450, family 11, subfamily A, polypeptide 1 (EC:1.14.15.6) C00033540 C00033541 C00036481
3295 HSD17B4, DBP, MFE-2, MPF-2, PRLTS1, SDR8C1 hydroxysteroid (17-beta) dehydrogenase 4 (EC:4.2.1.107 4.2.1.119 1.1.1.n12) C00033541 C00036465 C00036481
1585 CYP11B2, ALDOS, CPN2, CYP11B, CYP11BL, CYPXIB2, P-450C18, P450C18, P450aldo cytochrome P450, family 11, subfamily B, polypeptide 2 (EC:1.14.15.4 1.14.15.5) C00033540 C00033541 C00036465
1588 CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) C00033540 C00033541 C00036481
3292 HSD17B1, EDH17B2, EDHB17, HSD17, SDR28C1 hydroxysteroid (17-beta) dehydrogenase 1 (EC:1.1.1.62) C00033541 C00036465 C00036481
7276 TTR, CTS, CTS1, HsT2651, PALB, TBPA transthyretin C00033540 C00033541
1589 CYP21A2, CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B cytochrome P450, family 21, subfamily A, polypeptide 2 (EC:1.14.99.10) C00033540 C00036465
7031 TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 trefoil factor 1 C00033540
3156 HMGCR, LDLCQ3 3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34) C00033541

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P18054
#607208 Dravet syndrome P18507
#607681 Epilepsy, childhood absence, susceptibility to, 2; eca2 P18507
#611136 Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 P14867
#133239 Esophageal cancer P18054
#604233 Generalized epilepsy with febrile seizures plus, type 1; gefsp1 P18507
#611277 Generalized epilepsy with febrile seizures plus, type 3; gefsp3 P18507

KEGG DISEASE (2)

KEGG name UniProt
H00808 Idiopathic generalized epilepsies (IGEs) P14867 (related)
P18507 (related)
H00783 Febrile seizures P18507 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D011297 Prenatal Exposure Delayed Effects C00033540