PCIDB

KNApSAcK Metabolite C00003799

Metabolite

KNApSAcK Entry

id C00003799
Name 6-Hydroxy-4'-methoxyflavone
CAS RN 63046-09-3
Standard InChI InChI=1S/C16H12O4/c1-19-12-5-2-10(3-6-12)16-9-14(18)13-8-11(17)4-7-15(13)20-16/h2-9,17H,1H3
Standard InChI (Main Layer) InChI=1S/C16H12O4/c1-19-12-5-2-10(3-6-12)16-9-14(18)13-8-11(17)4-7-15(13)20-16/h2-9,17H,1H3

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 76

Link

ChEMBL

By standard InChI CHEMBL1339927
By standard InChI Main Layer CHEMBL1339927

KEGG

By LinkDB C14344

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 1

Family

family name count
Thymelaeaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Pimelea decora 586301 Thymelaeaceae rosids Viridiplantae

Human Protein / Gene in interaction

16 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q9NR56 Muscleblind-like protein 1 Unclassified protein CHEMBL1339927 CHEMBL1614166 (1)
1 / 0
O75496 Geminin Unclassified protein CHEMBL1339927 CHEMBL2114780 (1)
0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein CHEMBL1339927 CHEMBL1613838 (1)
0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme CHEMBL1339927 CHEMBL2114807 (1)
4 / 2
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL1339927 CHEMBL2114788 (1) CHEMBL2114931 (1)
0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein CHEMBL1339927 CHEMBL1614342 (1)
1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL1339927 CHEMBL1738588 (1) CHEMBL1738317 (1)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL1339927 CHEMBL1614421 (1)
4 / 3
Q9GZV3 High affinity choline transporter 1 Choline Na-symporter CHEMBL1339927 CHEMBL1794362 (1) CHEMBL1794546 (1)
1 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme CHEMBL1339927 CHEMBL1613829 (1)
0 / 0
O00255 Menin Unclassified protein CHEMBL1339927 CHEMBL1614257 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL1339927 CHEMBL1614257 (1)
1 / 3
Q00653 Nuclear factor NF-kappa-B p100 subunit Transcription Factor CHEMBL1339927 CHEMBL1613870 (1)
0 / 0
Q04206 Transcription factor p65 Transcription Factor CHEMBL1339927 CHEMBL1613870 (1)
0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor CHEMBL1339927 CHEMBL1613870 (1)
0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein CHEMBL1339927 CHEMBL2354287 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#158580 Neuronopathy, distal hereditary motor, type viia; hmn7a Q9GZV3
#257220 Niemann-pick disease, type c1; npc1 O15118
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (13)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00027 Ovarian cancer P38398 (related)
H00031 Breast cancer P38398 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)