PCIDB

KNApSAcK Metabolite C00038371

Metabolite

KNApSAcK Entry

id C00038371
Name Ageladine A
CAS RN 643020-13-7
Standard InChI InChI=1S/C10H7Br2N5/c11-4-3-6(15-9(4)12)7-8-5(1-2-14-7)16-10(13)17-8/h1-3,15H,(H3,13,16,17)
Standard InChI (Main Layer) InChI=1S/C10H7Br2N5/c11-4-3-6(15-9(4)12)7-8-5(1-2-14-7)16-10(13)17-8/h1-3,15H,(H3,13,16,17)

Cluster

Phytochemical cluster
KCF-S cluster No. 7827

Link

ChEMBL

By standard InChI CHEMBL230806
By standard InChI Main Layer CHEMBL230806

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count

Family

family name count
Agelasidae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Agelas nakamurai 279581 Agelasidae Metazoa

Human Protein / Gene in interaction

13 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q56UN5 Mitogen-activated protein kinase kinase kinase 19 STE serine/threonine protein kinase MEKK15 subfamily CHEMBL230806 CHEMBL2154879 (1)
0 / 0
P22894 Neutrophil collagenase M10A CHEMBL230806 CHEMBL2154851 (1)
0 / 0
P39900 Macrophage metalloelastase M10A CHEMBL230806 CHEMBL888901 (1) CHEMBL1046363 (1)
CHEMBL2154853 (1)
0 / 0
P14780 Matrix metalloproteinase-9 M10A CHEMBL230806 CHEMBL2154852 (1)
2 / 2
P11309 Serine/threonine-protein kinase pim-1 Pim CHEMBL230806 CHEMBL2155000 (1)
0 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 CHEMBL230806 CHEMBL2154997 (1)
0 / 0
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family CHEMBL230806 CHEMBL2154997 (1)
0 / 0
P50281 Matrix metalloproteinase-14 M10A CHEMBL230806 CHEMBL2154857 (1)
0 / 0
P29597 Non-receptor tyrosine-protein kinase TYK2 Jakb CHEMBL230806 CHEMBL2154877 (1)
1 / 1
P03956 Interstitial collagenase M10A CHEMBL230806 CHEMBL2154849 (1)
0 / 1
P45452 Collagenase 3 M10A CHEMBL230806 CHEMBL2154854 (1)
1 / 1
P08253 72 kDa type IV collagenase M10A CHEMBL230806 CHEMBL1046057 (1) CHEMBL2154850 (1)
CHEMBL2154855 (1)
1 / 3
Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A CMGC dual-specificity kinase DYRK1 CHEMBL230806 CHEMBL2154875 (1)
1 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#603932 Intervertebral disc disease; idd P14780
#614104 Mental retardation, autosomal dominant 7; mrd7 Q13627
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#602111 Spondyloepimetaphyseal dysplasia, missouri type P45452
#611521 Tyrosine kinase 2 deficiency P29597

KEGG DISEASE (5)

KEGG disease name UniProt
H00028 Choriocarcinoma P03956 (related)
P08253 (related)
H00025 Penile cancer P08253 (related)
P14780 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00479 Metaphyseal dysplasias P14780 (related)
P45452 (related)
H00107 Other well-defined immunodeficiency syndromes P29597 (related)