Species

KNApSAcK Entry

Organism name Agelas nakamurai
Genus
Family
Kingdom

NCBI taxonomy

Entry

Linked NCBI taxonomy name Agelas nakamurai
Linked NCBI taxonomy ID 279581
Linked level species

Family

Family in NCBI taxonomy Agelasidae
ID 85771

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Metazoa
ID 33208

Plant class

Plant class
ID

Metabolite list (17)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00050173 External link 512 Nakamurol A
/ (+)-Nakamurol A
No. 256 No. 46
C00038376 External link 512 Agelasine F
No. 2368
C00038375 External link 512 Agelasine E
No. 2368
C00038374 External link 512 Agelasine D
No. 2368
C00038372 External link 512 Agelasine B
C054174
No. 2368
C00038373 External link 512 Agelasine C
/ (-)-Agelasine C
No. 2368
C00029020 External link 512 Slagenin A
No. 3765
C00029021 External link 512 Slagenin B
/ (+)-Slagenin B
CHEMBL1991643
CHEMBL1996840
No. 3765
C00029022 External link 512 Slagenin C
/ (-)-Slagenin C
CHEMBL1991643
CHEMBL1996840
No. 3765
C00028610 External link 512 Mukanadin A
CHEMBL74098
No. 3889
C00022172 External link 512 Agelasidine B
No. 4066
C00011369 External link 512 Agelasidine A
No. 4066
C00022173 External link 512 Agelasidine C
CHEMBL484455
CHEMBL598329
C054173
No. 4066
C00028611 External link 512 Mukanadin B
No. 4600
C00038371 External link 512 Ageladine A
CHEMBL230806
13 / 6 / 5 No. 7827
C00028612 External link 512 Mukanadin C
CHEMBL449743
No. 8572
C00049957 External link 512 5-Bromopyrrole-2-(N-methoxymethyl)carboxamide
CHEMBL447040
No. 8938

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q56UN5 Mitogen-activated protein kinase kinase kinase 19 STE serine/threonine protein kinase MEKK15 subfamily C00038371 0 / 0
P22894 Neutrophil collagenase M10A C00038371 0 / 0
P39900 Macrophage metalloelastase M10A C00038371 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00038371 2 / 2
P11309 Serine/threonine-protein kinase pim-1 Pim C00038371 0 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 C00038371 0 / 0
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family C00038371 0 / 0
P50281 Matrix metalloproteinase-14 M10A C00038371 0 / 0
P29597 Non-receptor tyrosine-protein kinase TYK2 Jakb C00038371 1 / 1
P03956 Interstitial collagenase M10A C00038371 0 / 1
P45452 Collagenase 3 M10A C00038371 1 / 1
P08253 72 kDa type IV collagenase M10A C00038371 1 / 3
Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A CMGC dual-specificity kinase DYRK1 C00038371 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#603932 Intervertebral disc disease; idd P14780
#614104 Mental retardation, autosomal dominant 7; mrd7 Q13627
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#602111 Spondyloepimetaphyseal dysplasia, missouri type P45452
#611521 Tyrosine kinase 2 deficiency P29597

KEGG DISEASE (5)

KEGG name UniProt
H00028 Choriocarcinoma P03956 (related)
P08253 (related)
H00025 Penile cancer P08253 (related)
P14780 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00479 Metaphyseal dysplasias P14780 (related)
P45452 (related)
H00107 Other well-defined immunodeficiency syndromes P29597 (related)