KNApSAcK Metabolite C00040678
Metabolite
KNApSAcK Entry
| id | C00040678 |
|---|---|
| Name | Xanthone |
| CAS RN | 90-47-1 |
| Standard InChI | InChI=1S/C13H8O2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H |
| Standard InChI (Main Layer) | InChI=1S/C13H8O2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H |
Cluster
| Phytochemical cluster | No. 15 |
|---|---|
| KCF-S cluster | No. 76 |
Link
ChEMBL
| By standard InChI | CHEMBL186784 |
|---|---|
| By standard InChI Main Layer | CHEMBL186784 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN | C009689 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| rosids | 1 |
Family
| family name | count |
|---|---|
| Calophyllaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Calophyllum pinetorum | 73121 | Calophyllaceae | rosids | Viridiplantae |
Human Protein / Gene in interaction
12 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q16637 | Survival motor neuron protein | Unclassified protein | CHEMBL186784 |
CHEMBL1613842
(1)
|
4 / 2 |
| P04062 | Glucosylceramidase | Enzyme | CHEMBL186784 |
CHEMBL1613818
(1)
|
6 / 4 |
| P29466 | Caspase-1 | C14 | CHEMBL186784 |
CHEMBL1614158
(1)
|
0 / 0 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | CHEMBL186784 |
CHEMBL827909
(1)
|
1 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | CHEMBL186784 |
CHEMBL1614458
(1)
|
0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | CHEMBL186784 |
CHEMBL1614217
(1)
CHEMBL1614369
(1)
|
1 / 1 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | CHEMBL186784 |
CHEMBL1613910
(1)
|
3 / 3 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | CHEMBL186784 |
CHEMBL1614038
(1)
|
2 / 2 |
| P55210 | Caspase-7 | C14 | CHEMBL186784 |
CHEMBL1613779
(1)
|
0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL186784 |
CHEMBL1614108
(1)
CHEMBL1613886
(1)
|
0 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | CHEMBL186784 |
CHEMBL1614421
(1)
|
4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | CHEMBL186784 |
CHEMBL1613914
(1)
|
0 / 0 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (21)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #300615 | Brunner syndrome |
P21397
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
KEGG DISEASE (16)
| KEGG | disease name | UniProt |
|---|---|---|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
Q16637 (related) |
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|