PCIDB

KNApSAcK Metabolite C00000408

Metabolite

KNApSAcK Entry

id C00000408
Name EPA / Eicosapentaenoic acid
CAS RN 10417-94-4
Standard InChI InChI=1S/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-,16-15-
Standard InChI (Main Layer) InChI=1S/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22)

Cluster

Phytochemical cluster No. 50
KCF-S cluster No. 2002

Link

ChEMBL

By standard InChI CHEMBL460026
By standard InChI Main Layer CHEMBL460026

KEGG

By LinkDB C06428

CTD

By CAS RN

Species

Summary

Plant class

class name count

Family

family name count
Ceramiaceae 1

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Giffordia mitchellae
Ptilota filicina 153248 Ceramiaceae Eukaryota

Human Protein / Gene in interaction

12 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P49798 Regulator of G-protein signaling 4 Unclassified protein CHEMBL460026 CHEMBL1794499 (1)
2 / 0
P11473 Vitamin D3 receptor NR1I1 CHEMBL460026 CHEMBL1794311 (1)
2 / 3
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL460026 CHEMBL1614458 (1)
0 / 0
Q9UGP5 DNA polymerase lambda Enzyme CHEMBL460026 CHEMBL1921596 (1) CHEMBL1920071 (1)
0 / 0
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL460026 CHEMBL1614410 (1)
1 / 3
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme CHEMBL460026 CHEMBL1794467 (1)
0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 CHEMBL460026 CHEMBL976708 (1) CHEMBL976710 (1)
CHEMBL976711 (1)
2 / 2
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 CHEMBL460026 CHEMBL2072929 (1)
5 / 3
P13726 Tissue factor Membrane receptor CHEMBL460026 CHEMBL995691 (1)
0 / 0
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL460026 CHEMBL1794536 (1) CHEMBL1921592 (1)
CHEMBL1921595 (1)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL460026 CHEMBL1738442 (1)
0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL460026 CHEMBL2114738 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#137800 Glioma susceptibility 1; glm1 P37231
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#601665 Obesity P37231
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (10)

KEGG disease name UniProt
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P11511 (related)
H00794 Aromatase excess syndrome P11511 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)