PCIDB

KNApSAcK Metabolite C00048593

Metabolite

KNApSAcK Entry

id C00048593
Name 7-Amino-4-methylcoumarin
CAS RN 26093-31-2
Standard InChI InChI=1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3
Standard InChI (Main Layer) InChI=1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3

Cluster

Phytochemical cluster
KCF-S cluster No. 4529

Link

ChEMBL

By standard InChI CHEMBL270672
By standard InChI Main Layer CHEMBL270672

KEGG

By LinkDB C01386

CTD

By CAS RN C028743

Species

Summary

Plant class

class name count

Family

family name count
Xylariaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Xylaria sp. 37991 Xylariaceae Fungi

Human Protein / Gene in interaction

20 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P22310 UDP-glucuronosyltransferase 1-4 Enzyme CHEMBL270672 CHEMBL1908082 (1)
3 / 0
P04062 Glucosylceramidase Enzyme CHEMBL270672 CHEMBL1613818 (1)
6 / 4
P10253 Lysosomal alpha-glucosidase Hydrolase CHEMBL270672 CHEMBL1614175 (1) CHEMBL1614103 (1)
CHEMBL1614031 (1)
1 / 1
P29466 Caspase-1 C14 CHEMBL270672 CHEMBL1614158 (1)
0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL270672 CHEMBL1794585 (1)
0 / 0
P00918 Carbonic anhydrase 2 Lyase CHEMBL270672 CHEMBL1961262 (1)
1 / 2
Q9NR56 Muscleblind-like protein 1 Unclassified protein CHEMBL270672 CHEMBL1614166 (1)
1 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL270672 CHEMBL1614458 (1)
0 / 0
O43570 Carbonic anhydrase 12 Lyase CHEMBL270672 CHEMBL1961264 (1)
1 / 2
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL270672 CHEMBL1738606 (1)
0 / 0
P00915 Carbonic anhydrase 1 Lyase CHEMBL270672 CHEMBL1961261 (1)
0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL270672 CHEMBL2114788 (1)
0 / 0
P06280 Alpha-galactosidase A Enzyme CHEMBL270672 CHEMBL1614217 (1) CHEMBL1614369 (1)
1 / 1
Q16790 Carbonic anhydrase 9 Lyase CHEMBL270672 CHEMBL1961263 (1)
0 / 1
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL270672 CHEMBL1613910 (1) CHEMBL1614227 (1)
3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL270672 CHEMBL1614038 (1)
2 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL270672 CHEMBL1738317 (1)
0 / 0
P55210 Caspase-7 C14 CHEMBL270672 CHEMBL1613779 (1)
0 / 0
Q9UNA4 DNA polymerase iota Enzyme CHEMBL270672 CHEMBL1794483 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL270672 CHEMBL1613914 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (19)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#218800 Crigler-najjar syndrome, type i P22310
#606785 Crigler-najjar syndrome, type ii P22310
#119900 Digital clubbing, isolated congenital P15428
#301500 Fabry disease P06280
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#143500 Gilbert syndrome P22310
#232300 Glycogen storage disease ii P10253
#143860 Hyperchlorhidrosis, isolated O43570
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#168600 Parkinson disease, late-onset; pd P04062

KEGG DISEASE (15)

KEGG disease name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00125 Fabry disease P06280 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)